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Why Aren’t We Afraid of Death?: The First Step Toward Defeating Aging – Article by Alex Kadet

Why Aren’t We Afraid of Death?: The First Step Toward Defeating Aging – Article by Alex Kadet

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Alex Kadet


The pain of those fighting to extend human life expectancy

Science articles frequently mention the search for the “elixir of eternal youth.” What a pleasant thought! While we are busy living our lives, the science of extending them is moving at a dizzying pace, and we need only to wait until the international science community plates the solution, ready to serve, right? This statement illustrates how perceptions of reality are skewed toward desired outcomes.

Ask any reputable scientist, activist, or entrepreneur interested in extending human life about the subject, however, and you will learn that the reality is very different. For instance, here is a quotation from Aubrey de Grey, founder of the SENS (Strategies for Engineered Negligible Senescence) Research Foundation and pioneering researcher in the science of aging:

Aubrey de Grey

“. . . if I got a billion dollars today, we would probably bring forward the defeat of aging by about ten years. And it’s a lot of lives, maybe four hundred million.”

I suppose we all understand how insignificant one billion dollars is compared with the global annual expenditures on health care and science. The cost of health care in the United States alone exceeded 3.3 trillion dollars in 2016 and is growing rapidly.

What do these numbers mean? That, without a doubt, humanity is not even close to curing aging, even in the twenty-first century.

Longevity advocacy

At a glance, it seems odd that the idea of extending human life needs advocacy, but longevity scientists and advocates understand that the only obstacle to the development of a cure for aging is a lack of resources: time and money. The dollar has strong voting power, and human lifespan extension is not at the top of the ballot.

For some reason, not enough people are willing to do what objectively seems rational, to overcome the obstacles and diseases that aging causes. What appears to transhumanists, scientists, and researchers to be an undeniable benefit for humankind seems unimportant or even detrimental to others. Dying of old age seems dignified to some people, but in truth it is honorable only in the movies. Therefore, advocacy needs to be prioritized over seemingly more practical immediate problems.

Many people who work in the field of longevity studies are tormented by a fundamental question: If one acknowledges one’s mortality, isn’t working toward radical life extension a most rational use of one’s time? After all, millions of people, with trillions of dollars combined, have a nonzero chance of radically extending life expectancy within the next ten years.

A primary goal of longevity advocates is to attract investments and endorsements from international organizations, including scientific foundations and businesses, and increase the visibility and appeal of research on anti-aging therapy. We aim to market anti-aging science effectively, and raise the prestige of working in our industry to that of working for a venture-capital or tech startup.

Large-scale work must begin now, for a simple reason.

The population of the planet is rapidly aging.

The average age of the world populace is increasing at an alarming pace. Globally, the demographic comprising people aged sixty years or older is growing faster than any other group. If this trend continues, by 2050 the number of seniors in the world will more than double, from 962 million to 2.1 billion. Such a significant change in the composition of the population will inevitably affect economies and societies.

Throughout the history of humankind, aging has been viewed as an inevitable process, leading not so much to illness and suffering (which have always been treated as if separate from aging) but rather to physical death.

Let me draw your attention to the importance of distinguishing between improving the quality of life of the rapidly aging population and developing a treatment for aging.

It is also important to understand that when we talk about defeating aging, we do not put it as equal to immortality. Extending longevity will largely take the form of increasing productive life span and preventing suffering — not only fatigue, reduced physical strength, and impaired memory, but also the internal conflict of remaining young at heart and full of ambition in an aging body. Longevity specialists believe that victory over suffering is achievable and will be a victory over an absolute evil.

Why do we work so hard to treat the effects of aging while doing almost nothing to slow aging itself? Aging is literally a matter of life and death, and yet it commands almost no attention.

Life-Extension Myths

The vast majority of people and organizations (including the World Health Organization, billionaire entrepreneurs, the United Nations, and entire nations) do not include addressing the problems of aging in their short- or long-term agendas. They do not consider aging to be a real and distinct problem. Why not?

Maybe extending human life would be unnatural?

The answer is no.

  • Self-preservation is characteristic of all organisms and is one of the so-called “basic instincts” [1]. All organisms achieve self-preservation by purposefully reducing their own entropy (that is, using external resources to compensate for inevitable energy loss) and maintaining homeostasis (steady internal conditions).
  • People tend to consider aging and age-related diseases to be separate and distinct phenomena, as if aging is different from other abnormalities of the human body. Such thinking is fundamentally flawed. Most people do not have ethical problems with using medicine to treat suffering, but cognitive dissonance often produces ethical objections to therapies designed to treat aging, which is widely treated with dignity and respect, even viewed as sacred.
  • As the seventeenth-century philosopher Baruch Spinoza wrote in his Ethics, “The mind, both in so far as it has clear and distinct ideas, and also in so far as it has confused ideas, endeavors to persist in its being for an indefinite period, and of this endeavor it is conscious” [2]. It is human nature to attempt to survive as long as possible.

[For the interested reader: philosophical and ethical issues that inevitably arise in the fight against aging are discussed in detail in Steven Horrobin’s The Future of Aging, chapter three, “Towards Naturalistic Transcendence: The Value of Life and Life Extension to Persons as Conative Processes.”]

Perhaps the problem is that it is simply impossible to stop the human body from aging?

I don’t think so.

Gerontologists (people who study the science of aging) agree that slowing or preventing aging (that is, eliminating the faults of and repairing the accumulated damage to the body) is a purely technological problem and can be solved. Additionally, the existence of several animal species that are closely evolutionarily related to humans but live much longer than we do demonstrates that extended longevity is possible.

A “road map” for achieving longevity escape velocity has already been developed in the form of a series of specific steps and studies [4], [5]. We cannot predict which research will result in the elongation of the human life span, as there are multiple hypotheses to be tested, but if any current or future research yields actionable results, our most daring imaginings could be surpassed.

But what if we succeed in extending longevity and the resulting future is undesirable?

No, we will not die due to overpopulation.

  • The world’s human population has increased almost fourfold in the past one hundred years, and far from suffering as a result, we now live longer and enjoy greater quality of life than ever before. In fact, natural population decline is causing its own problems in several countries. In the 1970s, adherents of Thomas Malthus’s belief that unchecked population growth inevitably exhausts resources and yields poverty and degradation predicted a worldwide famine and demographic catastrophe by the year 2000. Their predictions did not come true, as they hadn’t taken into account the rapid expansion of agriculture and food production that did occur [6].

Decades will pass before the demographic consequences of victory over aging begin to impact our lives significantly. We will have enough time to adapt to the new circumstances [7].

No, the secret world elite cannot capture the “philosopher’s stone” and enslave the rest of us.

  • In the first years after antibiotics were discovered, they were available only to the rich. Similarly, today such complex and expensive medical interventions as organ transplantation are not widely available, but this is not a reason to ban them [7]. The treatment of aging will likely be very expensive initially, but as soon as the technology becomes known, endeavors to optimize it and expand its availability will inevitably begin. This is an axiom in modern society. It is already impossible (sometimes frighteningly) to keep significant information secret, and in the case of longevity studies, humanity will benefit.

In view of the preceding, we have no reason to doubt that victory over aging is achievable and will be favorable for humanity.

[For the interested reader: you can find more debunked myths here.]


Scientists and science advocates are working to dispel the above myths, but unfortunately their work has not yet produced the desired outcomes. Although it would seem that the possibility of a cure for aging would attract large amounts of resources and greatly impact human worldview and actions, we simply haven’t seen such an effect.

What if the motivation for our inaction doesn’t come from a rational place?

I believe that the general lack of interest in treating aging comes from a lack of fear of aging, as humans tend not to be consciously afraid of death. Where there is no fear of a phenomenon, there is no aim to eliminate it.

So, why aren’t we afraid of death?

  • Fear is a basic emotion based on the self-preservation instinct. It precipitates as a sudden cognitive and behavioral change stimulated by imminent danger [8].
  • Fear can reinforce social connections, such as when an escape for help calls for collective defense [9]. There are many threats in the world, and fear encourages us to change our behavior and unite in order to protect ourselves against them.

Cancer, terrorism, war, air crashes, environmental degradation, global climate change: these and many other dangers have been accounted for in the multibillion-dollar budgets of individual countries, international organizations, private foundations, and nonprofits. Aging is not on the list. I believe I know why.

In his Pulitzer Prize–winning book The Denial of Death, cultural anthropologist Ernest Becker explored the hypothesis that civilization is based not on the suppression of sexuality, as Sigmund Freud believed, but on the suppression of the inherent human fear of death.

Becker argued that at one extreme, civilization is a way for humankind to contain the anxiety of death, and at the other extreme, an individual’s character can be viewed as a complex of defenses against fear of death. In other words, all of our motivation, the whole set of human cognitive attitudes and emotional experiences, is aimed at avoiding the awareness of our own mortality [10].

Despite the fact that we will die someday, few of us think about mortality on a regular basis. In one way or another we become acquainted with death while still children, but our psyche is unable to process the phenomenon fully. Consequently, according to Becker, the unconscious mind forms a complex of balances and defenses that prevent contact with the horror of death.

The existential psychotherapist Irvin Yalom holds a similar point of view on the structure of the human psyche. In his book Existential Psychotherapy, he explores in detail how fear of death permeates the whole being, and how much of human activity implicitly results from this fear.

Mental defenses allow us to maintain mental health and keep from sliding into madness. On the other hand, the same defenses limit our freedom and program our reactions. Dependencies, workaholism, daily rituals, narcissism, anxiety, depression . . . The list of such defenses is long, and we utilize them to reduce our fear of death [11]. Becoming aware of one’s own defense strategies is the first step toward freedom from the limitations of the psyche and cognitive distortions.

Ernest Becker’s theory has been further developed and experimentally confirmed in the framework of terror management theory (TMT) [12]. For the first time in psychology, the horror of death has been studied as an experimental variable. In one study, researchers effected a horror of death in participants, activated their awareness of the inevitability of death, and studied the resulting defense mechanisms. Having experienced the anxiety of facing their own mortality, participants were asked to evaluate punishments for violators of cultural norms; these participants chose far more severe punishments than did the control group [13].

After thirty years of research, terror management theory maintains that the most basic reason death is upsetting and motivating is because it undermines the most basic motive of all, which is a prerequisite for all other need satisfaction — staying alive. More specifically, death is a unique motivator because (1) most of an organism’s biological systems function to keep the organism alive, thus averting death; (2) death must be avoided to enhance opportunities for reproduction and care of offspring, both of which are essential for gene perpetuation; (3) death is the only absolutely inevitable future event; and (4) death threatens to undermine all desires, whether for pleasure, belonging, certainty, meaning, control, competence, self-actualization, or growth [14]. I will discuss these facts in more detail in forthcoming articles.

Cultural worldview (religion, nationalism, etc.) and self-esteem are two common buffers that protect our unconscious from the anxiety of death. Almost every religion is predicated on a belief in an afterlife, thereby allowing adherents to control fear by ignoring or denying death. Also, self-esteem and culture fill life with value, helping us to surpass death symbolically by creating the illusion of continuing to exist through the contributions we make that will outlive us or because the community we identify with will continue to exist after our personal death [15].

Cognitive distortions, such as magical thinking or the denying to believe in our own mortality, push out existential questions from our conscious mind, gently urging us to concentrate on the less painful questions of being [12].

To begin truly active work on increasing human life expectancy and defeating age-related diseases, humankind needs to realize the finiteness of life.

Demystifying common defense mechanisms and the tricks our minds play to make us disregard our own mortality will be necessary in the fight against aging. Increasing awareness is often enough to motivate people to examine their defense mechanisms and resolve the cognitive distortions that make work on aging so unapproachable.

Right now, with modern science making possible technologies that had not even been imaginable before, it’s time to face our fear — to recognize the problem of human aging, and frame it not as a philosophical question of being but as an engineering challenge.

Readers of this article will probably not instantly become gerontologists (scientists specializing in the biology of aging) or sponsors of fundamental scientific research; however, an awareness that aging and death are real can only increase mindfulness for anyone who dares to face it, thus making them happier in the long run [16].

P.S.: Become a Radical Life Extension Hero! Support my research on the Patreon!

I am open to any discussion on the topic of longevity studies. Also, I am preparing a speech on the psychological effects of suppressing the fear of death. Experience shows that even a brief overview of this topic stimulates interest in the treatment of aging.

Furthermore, I am beginning research in the field of experimental social psychology and plan to use TMT techniques to identify optimal ways for delivering the message of longevity activists. If you are interested in collaboration of any kind, feel free to contact me here.

I’d like to thank Ekaterina Gorbacheva and Zachary Vigna for their editorial help.

Alex Kadet is a transhumanist, longevity activist, entrepreneur, and expert in death studies. He is also a member of the U.S. Transhumanist Party / Transhuman Party.

Sources:

[1] Pavlov I. P. “Twenty years of experience in the objective research of the higher nervous activity.” Science, Moscow, 1973: p. 237.

[2] Spinoza, B. Ethics. Part 3, proposition 9. 1677.

[3] Vishnevsky, A. G. “Reproduction of the population and society.” Мoscow, 1982: p. 110.

[4https://www.lifespan.io/the-rejuvenation-roadmap/

[5https://www.ted.com/talks/aubrey_de_grey_says_we_can_avoid_aging

[6] Trewavas, A. “Malthus foiled again and again.” Nature, 418 (6898), September 2002: pp. 668–670

[7] Sethe, S. & de Magalhaes, J. P. “Ethical Perspectives in Biogerontology.” In: Ethics, Health Policy and (Anti-) Aging: Mixed Blessings, ed. Schermer, M. & Pinxten, W. Springer, Dordrecht, Netherlands, 2013: pp. 173–188.

[8] Izard, I. The Emotions of Humans. Мoscow, 1980: p. 52–71.

[9] Eibl-Eibesfeldt, I. Ethology: The biology of behavior. Oxford, England, 1970

[10] Becker, E. The Denial of Death. Simon & Schuster, New York, 1973.

[11] Yalom, I. D. Existential Psychotherapy. Basic Books, New York”, 1980.

[12] Greenberg, J., Pyszczynski, T. & Solomon, S. “The causes and consequences of a need for self-esteem: A terror management theory.” In: Public Self and Private Self, ed. R. F. Baumeister. Springer-Verlag, New York, 1986: pp. 189–212.

[13] Rosenblatt, A., Greenberg, J., Solomon S., Pyszczynski, T. & Lyon, D. “Evidence for terror management theory: I. The effects of mortality salience on reactions to those who violate or uphold cultural values.” J. Pers. Soc. Psychol., Vol. 57, 1989: pp. 681–90.

[14] Pyszczynski, T., Solomon, S., & Greenberg, J. L. “Thirty Years of Terror Management Theory: From Genesis to Revelation.” Advances in Experimental Social Psychology, Vol. 52, 2015: pp. 1–70.

[15] Pyszczynski, T., Solomon, S., & Greenberg, J. L. (2015). Thirty Years of Terror Management Theory: From Genesis to Revelation. In Advances in Experimental Social Psychology (Vol. 52, pp. 1–70): Psychological Mechanisms Through Which Thoughts of Death Affect Behavior

[16] Killingsworth, M. A. & Gilbert, D. T.. “A Wandering Mind Is an Unhappy Mind.” Science, Vol. 330, issue 6006, 2010: p. 932.

2020 New Year’s and New Decade’s Message by Victor Bjoerk

2020 New Year’s and New Decade’s Message by Victor Bjoerk

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Victor Bjoerk


Picture of the M87 Black Hole – First-ever image of a black hole and a major accomplishment of the 2010s

Happy New Year and Decade, everyone!

I celebrated it this year in San Francisco, as I managed to get an opportunity in aging research here. I’ve always celebrated in Sweden before, with relatives or friends, and the last years’ celebrations have been with AI researcher Anders Sandberg. However, I’m certainly not stuck to any routine to mark it, and who knows where one may be in the future, if one may celebrate it in space even!

I still recall thinking about what would happen in the future back in 1999. Although, of course, our time calculation is completely arbitrary and not rooted in anything the universe cares about, we nonetheless like to set certain dates of when X event will happen when writing the history of humanity.

Back then I was a small child, and while I lacked a particular interest in aging research, I certainly read a lot of popular science and liked to think about what would happen during the upcoming millennia. Certainly, genetic enhancement of humans was high on that list and its happening now! Look, for example, at Luxturna and Zolgensma, the 2 approved gene therapies so far.

We should all be very happy to be alive now instead of during the previous 4 billion years life has existed. It’s been the best decade in history, ever. We have not only the basic logistics for keeping most people alive on a day-to-day basis with a good quality of life, but this also leads to a lot of spare time to develop technology.

Back in about 2008, when working in a nursing home as a teenager, I realized that I did not want to end up in that state within the next few decades. I did not feel that age-related disease belonged in an otherwise advanced high-tech society that respected human rights reasonably well. Since then, on most days, I’ve probably read new scientific papers on the topic, I went to university and studied molecular biology, I became director of Heales – which is a scientific think tank in Brussels – and set up the biannual EHA (Eurosymposium on Healthy Aging) conference series together with Sven Bulterijs.

I never intended to become a scientist for the sake of it; I just want to get the biggest problem in the history of humanity solved.

There are a lot of reasons for optimism. The 2010s saw unprecedented investment in this area, and many therapeutic aging interventions emerged. Among the ones most well-known are innovations in clearing senescent cells with senolytic drugs, leading to aging reversal.

So I just hope this trajectory of advancement continues as the public also becomes more informed. I’ve learnt that hype comes in cycles; lots of buzzwords and overoptimistic speculation flow around, but eventually also real products come out of the research (yes, even in biotechnology). The question is when enough therapies can be put together into an old person and systemically bring that person back to youth.

So I wish everyone a happy new year and decade, whatever your pursuits are, hoping that at the end of this decade we can summarize it, saying that we did what was possible.

I hope everyone had a fun celebration!

Victor Bjoerk has worked for the Gerontology Research Group, the Longevity Reporter, and the Fraunhofer-Institut für Zelltherapie und Immunologie. He has promoted awareness throughout Europe of emerging biomedical research and the efforts to reverse biological aging. He is now a molecular biologist and working for BioAge in San Francisco. 

Results of Platform Vote #7 and Adopted Sections

Results of Platform Vote #7 and Adopted Sections

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Gennady Stolyarov II


The U.S. Transhumanist Party conducted its twelfth vote of the members and the seventh vote on its platform planks between December 25, 2019, and January 1, 2020. Official ballot options can be found here.

Detailed results of the voting have been tabulated here. In one instance, where no majority was reached in the first round of voting, options were selected based on the ranked-preference method with instant runoffs.

As a result, the following new or amended sections of Article III of the U.S. Transhumanist Party Constitution were adopted.

Section LXXXIII [Adopted by a vote of the members during December 25, 2019 – January 1, 2020]: The United States Transhumanist Party / Transhuman Party opposes any development or deployment of weapons systems that are capable of killing or injuring human beings in the absence of an explicit command by a human being to take action in every specific instance. Autonomous drones, vehicles, or other combat systems may not be permitted to make life-or-death decisions on the basis of a program, algorithm, predictive model, or any other means other than a specific decision by a human being who is closely familiar with the circumstances surrounding any given military situation. Accordingly, the United States Transhumanist Party / Transhuman Party supports the Campaign to Stop Killer Robots and other initiatives to abolish all autonomous weapons and preclude the development of such weapons.

Section LXXXIV [Adopted by a vote of the members during December 25, 2019 – January 1, 2020]: The United States Transhumanist Party / Transhuman Party supports research into the process of ectogenesis, the ability of organisms to be incubated and to grow to the point of independent survival, within an artificial environment that provides such organisms with all the necessities of biological survival and development. Furthermore, the United States Transhumanist Party / Transhuman Party supports the widespread deployment and use of the technology of ectogenesis once such technology becomes safe and practical. Ectogenesis has the potential to benefit humans and other species alike, restoring extinct species and bolstering the numbers of endangered species, as well as alleviating the burdens of human pregnancy and rendering the divisive debate over abortion obsolete by reconciling the right to life of a fetus with the freedom of a woman to choose not to carry that fetus.

Section LXXXV [Adopted by a vote of the members during December 25, 2019 – January 1, 2020]: The United States Transhumanist Party / Transhuman Party supports any relaxation or elimination on caps in the United States federal budget regarding spending on scientific and technological research, including research in medicine and public health. Funding for science that can improve the human condition should not be subject to the vagaries of partisan political standoffs over the federal budget. Accordingly, the United States Transhumanist Party / Transhuman Party supports the Raise the Caps initiative and any other elimination of artificial restrictions of the allocations of funding to scientific and technological projects.

Section LXXXVI [Adopted by a vote of the members during December 25, 2019 – January 1, 2020]: The United States Transhumanist Party / Transhuman Party supports efforts to give citizens more accessible and safer ways to report misconduct, corruption, constitutional rights violations, international human rights violations, and other similar infractions by police, including local police departments, as well as by federal law-enforcement agencies, such as Customs and Border Protection (CBP), the Transportation Security Administration (TSA), and Immigration and Customs Enforcement (ICE), to an investigative organization, whether civilian in nature or a special investigative department within the judicial system.

Such efforts could, for example, involve having a mandate that every police department and federal law-enforcement agency website have a ‘banner’ on its website that allows citizens to report misbehavior by said police department or federal law-enforcement agency via a national reporting system. Reporting of misbehavior would not inhibit any constitutional rights, such as filing a lawsuit.

If a valid complaint is found after investigation, this could result in a fine, a reduction of funding, or a reduction of salary for the responsible officials as a means of punishment. Said money would be allocated back to the relevant level of government to increase the well-being of citizens.

A periodic report of all reported missteps by law-enforcement agencies should be made publicly available, including breakdowns of valid and invalid claims, as well as reports per region, among other useful breakdowns.

Section LXXXVII [Adopted by a vote of the members during December 25, 2019 – January 1, 2020]: The United States Transhumanist Party / Transhuman Party supports a requirement that any educational institution that receives federal funding must greatly reduce its expenditures on internal bureaucracy and administration, in part by eliminating the requirement for students to complete any hard-copy paperwork and by enabling ubiquitous free, electronic completion and submission of all required forms.

Section LXXXVIII [Adopted by a vote of the members during December 25, 2019 – January 1, 2020]: The United States Transhumanist Party / Transhuman Party supports a requirement that any educational institution that receives federal funding must openly publish all even partially federally funded research produced by that institution in readily downloadable electronic format without any cost to the general public, including any paywalls or access fees from academic journals that feature such research. This requirement would not apply to research projects solely supported by private funds or which do not require funding altogether; in those circumstances, the direct authors of such research would retain copyright to it and the ability to publish it in the manner they see fit.

Section LXXXIX [Adopted by a vote of the members during December 25, 2019 – January 1, 2020]: The United States Transhumanist Party / Transhuman Party supports a prohibition against police being equipped with military-grade hardware, including assault weapons, military armored vehicles, or any other offensive equipment primarily designed for battlefield use.

Section XC [Adopted by a vote of the members during December 25, 2019 – January 1, 2020]: The United States Transhumanist Party / Transhuman Party supports a requirement for police to be equipped with rubber bullets as standard ammunition and only to use regular, lethal bullets in situations where there is an immediate and previously known threat to the safety of members of the general public. More generally, police should be trained to use every possible technique for non-lethal incapacitation of offenders, prior to any recourse to lethal force.

Section XCI [Adopted by a vote of the members during December 25, 2019 – January 1, 2020]: The United States Transhumanist Party / Transhuman Party supports efforts to encourage police departments to use electric vehicles. This would have the advantages of reducing emissions of pollutants into the air, as well as moving police forces away from militarized vehicles, which are less likely to be electrically powered.

Section XCII [Adopted by a vote of the members during December 25, 2019 – January 1, 2020]: The United States Transhumanist Party / Transhuman Party supports the installment of monitoring systems in police vehicles to track whether the police are violating traffic laws, with the exception of situations where speeding or other technical infractions may be necessary to apprehend other known or suspected violators or criminal offenders. The ability of police to violate traffic laws with impunity is damaging to public perception, as law enforcement should first and foremost set an example for society to follow. By holding law enforcement accountable for minor infractions such as traffic violations, it will be possible to develop a police force that serves as an example to the public.

Section XCIII [Adopted by a vote of the members during December 25, 2019 – January 1, 2020]: The United States Transhumanist Party / Transhuman Party supports efforts to provide a path to legalization for all current undocumented immigrants living and working in the United States, free of restrictions based on country of origin, economic status, education, length of residency, or any other criteria, other than history of violent criminal activity.

Section XCIV [Adopted by a vote of the members during December 25, 2019 – January 1, 2020]: The United States Transhumanist Party / Transhuman Party supports efforts to end detention of all migrants for immigration violations not related to violent crimes. All current people serving jail terms for immigration issues with no additional crimes involved with the arrest must be released, and the path to citizenship started immediately. Those for whom an additional charge was involved would need to be reviewed on a case-by-case basis, with serious infractions – such as any violent offenses – potentially justifying additional detainment.

Section XCV [Adopted by a vote of the members during December 25, 2019 – January 1, 2020]:  The United States Transhumanist Party / Transhuman Party supports measures to modernize and streamline the immigration process and eliminate the backlogs for those already in the queue. The United States Transhumanist Party / Transhuman Party advocates simplifying the documentation process, eliminating all requirements for filling out hard-copy paperwork, and utilizing technology to cut wait times and bureaucratic delays.

Section XCVI [Adopted by a vote of the members during December 25, 2019 – January 1, 2020]: The United States Transhumanist Party / Transhuman Party supports the immediate abolition of all private prison facilities and the termination of arrangements with private contractors for detention or immigration and border enforcement. Punishment for crimes, expect for situations of self-defense from the immediate commission of a crime, should be a function reserved for government alone and should never involve a profit motive, which creates incentives to artificially inflate the appearance of criminal behavior and the punishment of lesser infractions. In order to preserve the capacity for inmates and detainees to be housed in humane conditions, the United States Federal Government, as well as State and local governments, should have the prerogative to appropriate the facilities previously used by private prisons and private detention contractors, after providing appropriate one-time compensation for the property involved.

Section XCVII [Adopted by a vote of the members during December 25, 2019 – January 1, 2020]: The United States Transhumanist Party / Transhuman Party supports the establishment of a federal land dividend, whereby currently unused federal lands, with the exception of national parks, national forests, and notable landmarks, will be leased to private corporations that agree to operate in an environmentally conscientious manner, with the proceeds of the lease funding a universal basic income for the United States population.

Moreover, Section XVI has been amended to read as follows:

Section XVI [Adopted by a vote of the members during March 26 – April 1, 2017; amended by a vote of the members during December 25, 2019 – January 1, 2020]: Irrespective of whether or not technology will eventually replace the need for the labor of sentient entities, the United States Transhumanist Party / Transhuman Party holds that all sentient entities should be the beneficiaries of an unconditional universal basic income, whereby the same minimum amount of money or other resources is provided irrespective of a sentient entity’s life circumstances, occupations, or other income sources, so as to provide a means for the basic requirements of existence and liberty to be met.

Official Ballot Options for Platform Vote #7

Official Ballot Options for Platform Vote #7

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The 7-day electronic voting period on the seventh set of proposed platform planks of the U.S. Transhumanist Party / Transhuman Party (15 potential planks and 1 potential amendment in total) will occur from 1:01 a.m. U.S. Pacific Time on December 25, 2019, to 1:01 a.m.  U.S. Pacific Time on January 1, 2020. All members of the U.S. Transhumanist Party / Transhuman Party (USTP) who have applied before 1:01 a.m. on December 25, 2019, will be eligible to vote, as long as they have expressed agreement with the three Core Ideals of the USTP or have otherwise been rendered eligible to vote at the discretion of the Chairman.

All members who are eligible to vote will be sent a link to an electronic submission form whereby they will be able to cast their ballot.

When you are voting, it is strongly recommended that you keep this page of official ballot options and the submission form open simultaneously in different windows so that you can reference the relevant options as you vote on them. Due to space limitations, the submission form does not list the entire text of all the options.

It is also recommended that you set aside at least thirty minutes to consider and vote on all of the options and read their text closely, as some of the options contain minor variations upon other options. 

For some questions, electronic voting is  conducted by a ranked-preference method on individual articles where more options are possible than would be accommodated by a simple “Yes” or “No” vote. Members should keep in mind that the ranked-preference method eliminates the incentives for strategic voting – so members are encouraged to vote for the options that reflect their individual preferences as closely as possible, without regard for how other members might vote.

Results of the voting will be tabulated during early January 2020, with the intent to announce the results approximately 7 days after all votes have been submitted.

NOTE: The titles of the questions and potential Sections are descriptive and informational only and will not appear in the final adopted platform planks (which will be incorporated into Article III of the U.S. Transhumanist Party Constitution). They are intended as concise guides to the subject matter of the questions and potential Sections. Likewise, the letters assigned to Sections within this ballot will not reflect the numbering of the final adopted provisions, which will depend on which Sections are selected by the membership.

NOTE II: The inclusion of any proposals on this ballot does not indicate any manner of endorsement for those proposals by the U.S. Transhumanist Party / Transhuman Party at this time – except to place those proposals before the members to determine the will of the members with regard to whether or not the U.S. Transhumanist Party / Transhuman Party Platform should incorporate any given proposal.


Voter Identification

E-mail address

Provide the same e-mail address you used to register for U.S. Transhumanist Party membership. Your ballot will be cross-referenced to our membership rolls, and only ballots with matching e-mail addresses will be counted.

What is your name?

At minimum, first and last name are required, unless you are publicly known by a single-name pseudonym which is not itself a common name. Your identity will not be publicly disclosed by the Transhumanist Party, unless you choose and/or authorize its disclosure. The nature of the selections made by the members may be disclosed, but, if they are, each individual vote will not be associated with the identity of the voter but rather will be presented in an anonymized manner.

Navigate the Options

Proposed Platform Sections

Question I. Section E7-A. Opposition to Autonomous Weapons
Question II. Section E7-B. Ectogenesis
Question III. Section E7-C. Elimination of Caps on Scientific Expenditures
Question IV. Section E7-D. Improved Reporting of Law-Enforcement Misconduct
Question V. Section E7-E. Requirement for Educational Institutions That Receive Federal Funding to Reduce Administrative Costs
Question VI. Section E7-F. Requirement for Educational Institutions That Receive Federal Funding to Publish Research Free of Charge to the General Public
Question VII. Section E7-G. Prohibition of Police from Carrying Military-Grade Hardware
Question VIII. Section E7-H. Requirement for Police to Use Rubber Bullets as Standard Ammunition
Question IX. Section E7-I. Encouragement for Police to Use Electric Vehicles
Question X. Section E7-J. Tracking of Police Violations of Traffic Laws
Question XI. Section E7-K. Path to Legalization of Current Immigrants
Question XII. Section E7-L. Elimination of Detention of Immigrants for Non-Violent Infractions
Question XIII. Section E7-M. Streamlining of Immigration Process
Question XIV. Section E7-N. Abolition of Private Prisons and Detention Facilities
Question XV. Section E7-O. Federal Land Dividend

Proposed Amendments to Existing Planks

Question XVI. Amendment to Section XVI on Universal Basic Income to Align with Version 3.0 of the Transhumanist Bill of Rights

Proposed Platform Sections

Question I. Section E7-A. Opposition to Autonomous Weapons

Shall the following language be adopted as a new Section within the U.S. Transhumanist Party / Transhuman Party Platform?

“The United States Transhumanist Party / Transhuman Party opposes any development or deployment of weapons systems that are capable of killing or injuring human beings in the absence of an explicit command by a human being to take action in every specific instance. Autonomous drones, vehicles, or other combat systems may not be permitted to make life-or-death decisions on the basis of a program, algorithm, predictive model, or any other means other than a specific decision by a human being who is closely familiar with the circumstances surrounding any given military situation. Accordingly, the United States Transhumanist Party / Transhuman Party supports the Campaign to Stop Killer Robots and other initiatives to abolish all autonomous weapons and preclude the development of such weapons.”

Select one of the following options.

Yes.

No.

Abstain.

Question II. Section E7-B. Ectogenesis

Shall the following language be adopted as a new Section within the U.S. Transhumanist Party / Transhuman Party Platform?

“The United States Transhumanist Party / Transhuman Party supports research into the process of ectogenesis, the ability of organisms to be incubated and to grow to the point of independent survival, within an artificial environment that provides such organisms with all the necessities of biological survival and development. Furthermore, the United States Transhumanist Party / Transhuman Party supports the widespread deployment and use of the technology of ectogenesis once such technology becomes safe and practical. Ectogenesis has the potential to benefit humans and other species alike, restoring extinct species and bolstering the numbers of endangered species, as well as alleviating the burdens of human pregnancy and rendering the divisive debate over abortion obsolete by reconciling the right to life of a fetus with the freedom of a woman to choose not to carry that fetus.”

Select one of the following options.

Yes.

No.

Abstain.

Question III. Section E7-C. Elimination of Caps on Scientific Expenditures

Rank-order the Section E7-C Options that you support. Choose “1” for your most highly favored option, “2” for your second-most highly favored option, etc. You may include the option for “No Section of this sort” in your rank-ordering, and it does not need to be your most favored option if you do so. (For instance, some voters might favor some options but think that no language is preferable to some of the other options.)

If you choose “Abstain”, then do not rank-order any options, as you will be considered to have skipped this question.

☐ Option E7-C-1. [Based on Suggestion by John Marlowe] The United States Transhumanist Party / Transhuman Party supports any relaxation or elimination on caps in the United States federal budget regarding spending on peaceful scientific and technological research, including research in medicine and public health. Funding for science that can improve the human condition should not be subject to the vagaries of partisan political standoffs over the federal budget. Accordingly, the United States Transhumanist Party / Transhuman Party supports the Raise the Caps initiative and any other elimination of artificial restrictions of the allocations of funding to peaceful scientific and technological projects.

Option E7-C-2. [Modification by Jared V to Remove the Adjective “Peaceful” in Reference to Scientific and Technological Projects] The United States Transhumanist Party / Transhuman Party supports any relaxation or elimination on caps in the United States federal budget regarding spending on scientific and technological research, including research in medicine and public health. Funding for science that can improve the human condition should not be subject to the vagaries of partisan political standoffs over the federal budget. Accordingly, the United States Transhumanist Party / Transhuman Party supports the Raise the Caps initiative and any other elimination of artificial restrictions of the allocations of funding to scientific and technological projects.

☐ Option E7-C-NO. No Section of this sort.

Question IV. Section E7-D. Improved Reporting of Law-Enforcement Misconduct

Shall the following language be adopted as a new Section within the U.S. Transhumanist Party / Transhuman Party Platform?

“The United States Transhumanist Party / Transhuman Party supports efforts to give citizens more accessible and safer ways to report misconduct, corruption, constitutional rights violations, international human rights violations, and other similar infractions by police, including local police departments, as well as by federal law-enforcement agencies, such as Customs and Border Protection (CBP), the Transportation Security Administration (TSA), and Immigration and Customs Enforcement (ICE), to an investigative organization, whether civilian in nature or a special investigative department within the judicial system.

“Such efforts could, for example, involve having a mandate that every police department and federal law-enforcement agency website have a ‘banner’ on its website that allows citizens to report misbehavior by said police department or federal law-enforcement agency via a national reporting system. Reporting of misbehavior would not inhibit any constitutional rights, such as filing a lawsuit.

“If a valid complaint is found after investigation, this could result in a fine, a reduction of funding, or a reduction of salary for the responsible officials as a means of punishment. Said money would be allocated back to the relevant level of government to increase the well-being of citizens.

“A periodic report of all reported missteps by law-enforcement agencies should be made publicly available, including breakdowns of valid and invalid claims, as well as reports per region, among other useful breakdowns.”

Yes.

No.

Abstain.

Question V. Section E7-E. Requirement for Educational Institutions That Receive Federal Funding to Reduce Administrative Costs

Shall the following language be adopted as a new Section within the U.S. Transhumanist Party / Transhuman Party Platform?

“The United States Transhumanist Party / Transhuman Party supports a requirement that any educational institution that receives federal funding must greatly reduce its expenditures on internal bureaucracy and administration, in part by eliminating the requirement for students to complete any hard-copy paperwork and by enabling ubiquitous free, electronic completion and submission of all required forms.”

Yes.

No.

Abstain.

Question VI. Section E7-F. Requirement for Educational Institutions That Receive Federal Funding to Publish Research Free of Charge to the General Public

Shall the following language be adopted as a new Section within the U.S. Transhumanist Party / Transhuman Party Platform?

“The United States Transhumanist Party / Transhuman Party supports a requirement that any educational institution that receives federal funding must openly publish all even partially federally funded research produced by that institution in readily downloadable electronic format without any cost to the general public, including any paywalls or access fees from academic journals that feature such research. This requirement would not apply to research projects solely supported by private funds or which do not require funding altogether; in those circumstances, the direct authors of such research would retain copyright to it and the ability to publish it in the manner they see fit.”

Yes.

No.

Abstain.

Question VII. Section E7-G. Prohibition of Police from Carrying Military-Grade Hardware

Shall the following language be adopted as a new Section within the U.S. Transhumanist Party / Transhuman Party Platform?

“The United States Transhumanist Party / Transhuman Party supports a prohibition against police being equipped with military-grade hardware, including assault weapons, military armored vehicles, or any other offensive equipment primarily designed for battlefield use.”

Yes.

No.

Abstain.

Question VIII. Section E7-H. Requirement for Police to Use Rubber Bullets as Standard Ammunition

Shall the following language be adopted as a new Section within the U.S. Transhumanist Party / Transhuman Party Platform?

“The United States Transhumanist Party / Transhuman Party supports a requirement for police to be equipped with rubber bullets as standard ammunition and only to use regular, lethal bullets in situations where there is an immediate and previously known threat to the safety of members of the general public. More generally, police should be trained to use every possible technique for non-lethal incapacitation of offenders, prior to any recourse to lethal force.”

Yes.

No.

Abstain.

Question IX. Section E7-I. Encouragement for Police to Use Electric Vehicles

Shall the following language be adopted as a new Section within the U.S. Transhumanist Party / Transhuman Party Platform?

“The United States Transhumanist Party / Transhuman Party supports efforts to encourage police departments to use electric vehicles. This would have the advantages of reducing emissions of pollutants into the air, as well as moving police forces away from militarized vehicles, which are less likely to be electrically powered.”

Yes.

No.

Abstain.

Question X. Section E7-J. Tracking of Police Violations of Traffic Laws

Shall the following language be adopted as a new Section within the U.S. Transhumanist Party / Transhuman Party Platform?

“The United States Transhumanist Party / Transhuman Party supports the installment of monitoring systems in police vehicles to track whether the police are violating traffic laws, with the exception of situations where speeding or other technical infractions may be necessary to apprehend other known or suspected violators or criminal offenders. The ability of police to violate traffic laws with impunity is damaging to public perception, as law enforcement should first and foremost set an example for society to follow. By holding law enforcement accountable for minor infractions such as traffic violations, it will be possible to develop a police force that serves as an example to the public.”

Yes.

No.

Abstain.

Question XI. Section E7-K. Path to Legalization of Current Immigrants

Shall the following language be adopted as a new Section within the U.S. Transhumanist Party / Transhuman Party Platform?

“The United States Transhumanist Party / Transhuman Party supports efforts to provide a path to legalization for all current undocumented immigrants living and working in the United States, free of restrictions based on country of origin, economic status, education, length of residency, or any other criteria, other than history of violent criminal activity.”

Yes.

No.

Abstain.

Question XII. Section E7-L. Elimination of Detention of Immigrants for Non-Violent Infractions

Shall the following language be adopted as a new Section within the U.S. Transhumanist Party / Transhuman Party Platform?

“The United States Transhumanist Party / Transhuman Party supports efforts to end detention of all migrants for immigration violations not related to violent crimes. All current people serving jail terms for immigration issues with no additional crimes involved with the arrest must be released, and the path to citizenship started immediately. Those for whom an additional charge was involved would need to be reviewed on a case-by-case basis, with serious infractions – such as any violent offenses – potentially justifying additional detainment.”

Yes.

No.

Abstain.

Question XIII. Section E7-M. Streamlining of Immigration Process

Shall the following language be adopted as a new Section within the U.S. Transhumanist Party / Transhuman Party Platform?

“The United States Transhumanist Party / Transhuman Party supports measures to modernize and streamline the immigration process and eliminate the backlogs for those already in the queue. The United States Transhumanist Party / Transhuman Party advocates simplifying the documentation process, eliminating all requirements for filling out hard-copy paperwork, and utilizing technology to cut wait times and bureaucratic delays.”

Yes.

No.

Abstain.

Question XIV. Section E7-N. Abolition of Private Prisons and Detention Facilities

Shall the following language be adopted as a new Section within the U.S. Transhumanist Party / Transhuman Party Platform?

“The United States Transhumanist Party / Transhuman Party supports the immediate abolition of all private prison facilities and the termination of arrangements with private contractors for detention or immigration and border enforcement. Punishment for crimes, expect for situations of self-defense from the immediate commission of a crime, should be a function reserved for government alone and should never involve a profit motive, which creates incentives to artificially inflate the appearance of criminal behavior and the punishment of lesser infractions. In order to preserve the capacity for inmates and detainees to be housed in humane conditions, the United States Federal Government, as well as State and local governments, should have the prerogative to appropriate the facilities previously used by private prisons and private detention contractors, after providing appropriate one-time compensation for the property involved.”

Yes.

No.

Abstain.

Question XV. Section E7-O. Federal Land Dividend

Rank-order the Section E7-O Options that you support. Choose “1” for your most highly favored option, “2” for your second-most highly favored option, etc. You may include the option for “No Section of this sort” in your rank-ordering, and it does not need to be your most favored option if you do so. (For instance, some voters might favor some options but think that no language is preferable to some of the other options.)

If you choose “Abstain”, then do not rank-order any options, as you will be considered to have skipped this question.

Option E7-O-1. The United States Transhumanist Party / Transhuman Party supports the establishment of a federal land dividend, whereby currently unused federal lands, with the exception of national parks and notable landmarks, will be leased to private corporations that agree to operate in an environmentally conscientious manner, with the proceeds of the lease funding a universal basic income for the United States population.

Option E7-O-2. [Modification by Jared V to Include National Forests as Protected Lands] The United States Transhumanist Party / Transhuman Party supports the establishment of a federal land dividend, whereby currently unused federal lands, with the exception of national parks, national forests, and notable landmarks, will be leased to private corporations that agree to operate in an environmentally conscientious manner, with the proceeds of the lease funding a universal basic income for the United States population.

☐ Option E7-O-NO. No Section of this sort.

Proposed Amendments to Existing Planks

Question XVI. Amendment to Section XVI on Universal Basic Income to Align with Version 3.0 of the Transhumanist Bill of Rights

Shall the current version of Section XVI be retained in the United States Transhumanist Party / Transhuman Party Platform, or shall Section XVI be amended as stated in Amendment XVI-1 below?

Select one of the following options.

☐ Current Version of Section XVI. Given the inevitability of technology eventually replacing the need for the labor of sentient entities, the United States Transhumanist Party holds that all sentient entities should be the beneficiaries of an unconditional universal basic income, whereby the same minimum amount of money or other resources is provided irrespective of a sentient entity’s life circumstances, occupations, or other income sources, so as to provide a means for the basic requirements of existence and liberty to be met.

☐ Amendment XVI-1. [Revision to Align with Article XIX Version 3.0 of the Transhumanist Bill of Rights]

Irrespective of whether or not technology will eventually replace the need for the labor of sentient entities, the United States Transhumanist Party / Transhuman Party holds that all sentient entities should be the beneficiaries of an unconditional universal basic income, whereby the same minimum amount of money or other resources is provided irrespective of a sentient entity’s life circumstances, occupations, or other income sources, so as to provide a means for the basic requirements of existence and liberty to be met.

 Abstain.

24-Day Exposure Period for Platform Vote #7

24-Day Exposure Period for Platform Vote #7

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Gennady Stolyarov II


For its upcoming seventh Platform vote, the U.S. Transhumanist Party / Transhuman Party (USTP) has received a large volume of suggestions from members. This exposure period is intended to encompass the most salient of these suggestions. The forthcoming Platform vote is intended to “catch up” on the processing of suggestions that could not be immediately addressed due to limited resources in the course of the 2019 Presidential Primary season. It is likely that additional Platform votes will follow in early 2020 to address remaining items of interest to the USTP membership.

A vote will be scheduled on some or all of these items once they have been exposed for at least 24 days. For each item, a 7-day voting period is expected to be opened at the earliest on Wednesday, December 25, 2019.

During the exposure period, please post your comments on this thread. If you post comments intended to be considered in voting and/or amending any of these planks in any other electronic medium, please note that you thereby give your consent to have your comments reproduced with attribution or linked within this discussion thread, in order to direct members’ attention and consideration to them.

After the exposure period, a 7-day electronic voting period will occur. Instructions for electronic voting will be sent to members of the U.S. Transhumanist Party / Transhuman Party via e-mail at that time. All individuals who are members of the U.S. Transhumanist Party as of the end of the exposure period and who have expressed agreement with its three Core Ideals will be eligible to vote thereafter. You can still vote if you become a member during the exposure period, so please apply here if you are interested. During the 7-day electronic voting period, you will still be able to become a member – but you will only be able to vote in subsequent elections, since we seek for voting on any given issue to be done by those members who have had an opportunity to thoroughly consider that issue and be involved in deliberations regarding it.

Electronic voting will be conducted by a ranked-preference method if more than a single option is presented for the wording of a particular plank or segment of a plank. Members will be able to rank-order their preferred selections on each individual Platform Section. The original text of each Section will be available for selection, as well as any reasonable amendments proposed by any member. Leadership of the U.S. Transhumanist Party / Transhuman Party reserves the right to edit any proposed amendment for correctness of spelling and grammar. “No Section of this sort” will also be a choice, and any Section where a majority of votes favors this option will be not be adopted. Members will also be able to abstain from voting on any given Section.

The ranked-preference method has the advantage of eliminating a “winner-take-all” or “first-past-the-post” mentality and preventing people from being channeled into voting for sub-optimal choices (in their view) just because they fear an even less palatable alternative prevailing. Within the ranked-preference methodology, if no option obtains a clear majority as voters’ first choice, the option having the fewest first-choice votes is eliminated from consideration, and all those who voted for that option will have their votes assigned to their second-choice options. This process of elimination continues until one particular option has a clear majority of votes.

The U.S. Transhumanist Party / Transhuman Party encourages all members to participate in this process and for other transhumanists to sign up for membership during the exposure period. 

The Section titles below are provisional and will be replaced with official numbers for each plank that is adopted. The Section titles are informational only and will not be included in the adopted versions of the platform planks.


Section E7-A. Opposition to Autonomous Weapons

Option E7-A-1. [Based on Suggestion by Mike DiVerde and Dan Elton] The United States Transhumanist Party / Transhuman Party opposes any development or deployment of weapons systems that are capable of killing or injuring human beings in the absence of an explicit command by a human being to take action in every specific instance. Autonomous drones, vehicles, or other combat systems may not be permitted to make life-or-death decisions on the basis of a program, algorithm, predictive model, or any other means other than a specific decision by a human being who is closely familiar with the circumstances surrounding any given military situation. Accordingly, the United States Transhumanist Party / Transhuman Party supports the Campaign to Stop Killer Robots and other initiatives to abolish all autonomous weapons and preclude the development of such weapons.

Section E7-B. Ectogenesis

Option E7-B-1. The United States Transhumanist Party / Transhuman Party supports research into the process of ectogenesis, the ability of organisms to be incubated and to grow to the point of independent survival, within an artificial environment that provides such organisms with all the necessities of biological survival and development. Furthermore, the United States Transhumanist Party / Transhuman Party supports the widespread deployment and use of the technology of ectogenesis once such technology becomes safe and practical. Ectogenesis has the potential to benefit humans and other species alike, restoring extinct species and bolstering the numbers of endangered species, as well as alleviating the burdens of human pregnancy and rendering the divisive debate over abortion obsolete by reconciling the right to life of a fetus with the freedom of a woman to choose not to carry that fetus.

Section E7-C. Elimination of Caps on Scientific Expenditures

Option E7-C-1. [Based on Suggestion by John Marlowe] The United States Transhumanist Party / Transhuman Party supports any relaxation or elimination on caps in the United States federal budget regarding spending on peaceful scientific and technological research, including research in medicine and public health. Funding for science that can improve the human condition should not be subject to the vagaries of partisan political standoffs over the federal budget. Accordingly, the United States Transhumanist Party / Transhuman Party supports the Raise the Caps initiative and any other elimination of artificial restrictions of the allocations of funding to peaceful scientific and technological projects.

Option E7-C-2. [Modification by Jared V to Remove the Adjective “Peaceful” in Reference to Scientific and Technological Projects] The United States Transhumanist Party / Transhuman Party supports any relaxation or elimination on caps in the United States federal budget regarding spending on scientific and technological research, including research in medicine and public health. Funding for science that can improve the human condition should not be subject to the vagaries of partisan political standoffs over the federal budget. Accordingly, the United States Transhumanist Party / Transhuman Party supports the Raise the Caps initiative and any other elimination of artificial restrictions of the allocations of funding to scientific and technological projects.

Section E7-D. Improved Reporting of Law-Enforcement Misconduct

Option E7-D-1. [Based on Suggestion by Martin van der Kroon]

The United States Transhumanist Party / Transhuman Party supports efforts to give citizens more accessible and safer ways to report misconduct, corruption, constitutional rights violations, international human rights violations, and other similar infractions by police, including local police departments, as well as by federal law-enforcement agencies, such as Customs and Border Protection (CBP), the Transportation Security Administration (TSA), and Immigration and Customs Enforcement (ICE), to an investigative organization, whether civilian in nature or a special investigative department within the judicial system.

Such efforts could, for example, involve having a mandate that every police department and federal law-enforcement agency website have a ‘banner’ on its website that allows citizens to report misbehavior by said police department or federal law-enforcement agency via a national reporting system. Reporting of misbehavior would not inhibit any constitutional rights, such as filing a lawsuit.

If a valid complaint is found after investigation, this could result in a fine, a reduction of funding, or a reduction of salary for the responsible officials as a means of punishment. Said money would be allocated back to the relevant level of government to increase the well-being of citizens.

A periodic report of all reported missteps by law-enforcement agencies should be made publicly available, including breakdowns of valid and invalid claims, as well as reports per region, among other useful breakdowns.

Section E7-E. Requirement for Educational Institutions That Receive Federal Funding to Reduce Administrative Costs

Option E7-E-1. [Based on Suggestion by Martin van der Kroon]

The United States Transhumanist Party / Transhuman Party supports a requirement that any educational institution that receives federal funding must greatly reduce its expenditures on internal bureaucracy and administration, in part by eliminating the requirement for students to complete any hard-copy paperwork and by enabling ubiquitous free, electronic completion and submission of all required forms.

Section E7-F. Requirement for Educational Institutions That Receive Federal Funding to Publish Research Free of Charge to the General Public

Option E7-F-1. The United States Transhumanist Party / Transhuman Party supports a requirement that any educational institution that receives federal funding must openly publish all even partially federally funded research produced by that institution in readily downloadable electronic format without any cost to the general public, including any paywalls or access fees from academic journals that feature such research. This requirement would not apply to research projects solely supported by private funds or which do not require funding altogether; in those circumstances, the direct authors of such research would retain copyright to it and the ability to publish it in the manner they see fit.

Section E7-G. Prohibition of Police from Carrying Military-Grade Hardware

Option E7-G-1. [Based on Suggestion by Martin van der Kroon]

The United States Transhumanist Party / Transhuman Party supports a prohibition against police being equipped with military-grade hardware, including assault weapons, military armored vehicles, or any other offensive equipment primarily designed for battlefield use.

Section E7-H. Requirement for Police to Use Rubber Bullets as Standard Ammunition

Option E7-H-1. [Based on Suggestion by Martin van der Kroon]

The United States Transhumanist Party / Transhuman Party supports a requirement for police to be equipped with rubber bullets as standard ammunition and only to use regular, lethal bullets in situations where there is an immediate and previously known threat to the safety of members of the general public. More generally, police should be trained to use every possible technique for non-lethal incapacitation of offenders, prior to any recourse to lethal force.

Section E7-I. Encouragement for Police to Use Electric Vehicles

Option E7-I-1. [Based on Suggestion by R. Nicholas Starr]

The United States Transhumanist Party / Transhuman Party supports efforts to encourage police departments to use electric vehicles. This would have the advantages of reducing emissions of pollutants into the air, as well as moving police forces away from militarized vehicles, which are less likely to be electrically powered.

Section E7-J. Tracking of Police Violations of Traffic Laws

Option E7-J-1. [Based on Suggestion by Martin van der Kroon]

The United States Transhumanist Party / Transhuman Party supports the installment of monitoring systems in police vehicles to track whether the police are violating traffic laws, with the exception of situations where speeding or other technical infractions may be necessary to apprehend other known or suspected violators or criminal offenders. The ability of police to violate traffic laws with impunity is damaging to public perception, as law enforcement should first and foremost set an example for society to follow. By holding law enforcement accountable for minor infractions such as traffic violations, it will be possible to develop a police force that serves as an example to the public.

Section E7-K. Path to Legalization of Current Immigrants

Option E7-K-1. [Based on Suggestion by Jennifer Huse]

The United States Transhumanist Party / Transhuman Party supports efforts to provide a path to legalization for all current undocumented immigrants living and working in the United States, free of restrictions based on country of origin, economic status, education, length of residency, or any other criteria, other than history of violent criminal activity.

Section E7-L. Elimination of Detention of Immigrants for Non-Violent Infractions

Option E7-L-1. [Based on Suggestion by Jennifer Huse]

The United States Transhumanist Party / Transhuman Party supports efforts to end detention of all migrants for immigration violations not related to violent crimes. All current people serving jail terms for immigration issues with no additional crimes involved with the arrest must be released, and the path to citizenship started immediately. Those for whom an additional charge was involved would need to be reviewed on a case-by-case basis, with serious infractions – such as any violent offenses – potentially justifying additional detainment.

Section E7-M. Streamlining of Immigration Process

Option E7-M-1. [Based on Suggestion by Jennifer Huse]

The United States Transhumanist Party / Transhuman Party supports measures to modernize and streamline the immigration process and eliminate the backlogs for those already in the queue. The United States Transhumanist Party / Transhuman Party advocates simplifying the documentation process, eliminating all requirements for filling out hard-copy paperwork, and utilizing technology to cut wait times and bureaucratic delays.

Section E7-N. Abolition of Private Prisons and Detention Facilities

Option E7-N-1. [Based on Suggestion by Jennifer Huse, with Expansions]

The United States Transhumanist Party / Transhuman Party supports the immediate abolition of all private prison facilities and the termination of arrangements with private contractors for detention or immigration and border enforcement. Punishment for crimes, expect for situations of self-defense from the immediate commission of a crime, should be a function reserved for government alone and should never involve a profit motive, which creates incentives to artificially inflate the appearance of criminal behavior and the punishment of lesser infractions. In order to preserve the capacity for inmates and detainees to be housed in humane conditions, the United States Federal Government, as well as State and local governments, should have the prerogative to appropriate the facilities previously used by private prisons and private detention contractors, after providing appropriate one-time compensation for the property involved.

Section E7-O. Federal Land Dividend

Option E7-O-1.

The United States Transhumanist Party / Transhuman Party supports the establishment of a federal land dividend, whereby currently unused federal lands, with the exception of national parks and notable landmarks, will be leased to private corporations that agree to operate in an environmentally conscientious manner, with the proceeds of the lease funding a universal basic income for the United States population.

Option E7-O-2. [Modification by Jared V to Include National Forests as Protected Lands]

The United States Transhumanist Party / Transhuman Party supports the establishment of a federal land dividend, whereby currently unused federal lands, with the exception of national parks, national forests, and notable landmarks, will be leased to private corporations that agree to operate in an environmentally conscientious manner, with the proceeds of the lease funding a universal basic income for the United States population.

Proposed Amendments to Existing Planks

Members will be given the option to either retain existing language of a plank or to adopt any of the listed proposed amendments. Ranked-preference voting will be conducted for any Section for which more than one amendment has been proposed. Members will also be able to abstain from each vote.

1. Amendments to Section XVI on Universal Basic Income to Align with Version 3.0 of the Transhumanist Bill of Rights

Current Version of Section XVI. Given the inevitability of technology eventually replacing the need for the labor of sentient entities, the United States Transhumanist Party holds that all sentient entities should be the beneficiaries of an unconditional universal basic income, whereby the same minimum amount of money or other resources is provided irrespective of a sentient entity’s life circumstances, occupations, or other income sources, so as to provide a means for the basic requirements of existence and liberty to be met.

Amendment XVI-1. [Revision to Align with Article XIX Version 3.0 of the Transhumanist Bill of Rights]

Irrespective of whether or not technology will eventually replace the need for the labor of sentient entities, the United States Transhumanist Party / Transhuman Party holds that all sentient entities should be the beneficiaries of an unconditional universal basic income, whereby the same minimum amount of money or other resources is provided irrespective of a sentient entity’s life circumstances, occupations, or other income sources, so as to provide a means for the basic requirements of existence and liberty to be met.

California is Right to Allow Women to Sell Their Eggs for Research – Statement by Justin Waters

California is Right to Allow Women to Sell Their Eggs for Research – Statement by Justin Waters

Justin Waters


Women will now be fairly compensated for donating their oocytes (eggs) for research purposes. On October 13, 2019, Governor Gavin Newsom of California approved . The bill passed with a unanimous vote in the Senate and a vote of 28 to 4 in the Assembly.

California Assemblywoman Autumn Burke sponsored AB-922.

Prior to the passage of AB-922, California was one of only three states to prohibit payment to those who donate eggs. The American Society for Reproductive Medicine  allowing fair compensation will improve reproductive research by increasing the availability of eggs and continue California’s status as a leader in biotechnology.

The bill requires research programs to submit their patients’ de-identified demographic and medical data to California’s Legislative Analyst’s Office on or before January 16, 2023. The purpose of collecting such data appears to be for medical knowledge and to ensure compensation does not result in exploitation.

The bill was sponsored by California Assemblywoman Autumn Burke, a woman who has undergone egg harvesting four times for her own fertility treatments. She told the, “there’s very little data to show that this process has any detrimental effects.”

Allowing compensation benefits both the participants and the community because it allows women to be financially compensated for participating in research, and it improves the community by improving medical knowledge. Women have the bodily freedom to choose whether to participate in an egg-retrieval process, and it is ethically right that women who provide eggs for research are fairly compensated.

Justin Waters is the Legislative Director of the United States Transhumanist Party / Transhuman Party.

Human Pilot Study Results for Senolytics Published – Article by Steve Hill

Human Pilot Study Results for Senolytics Published – Article by Steve Hill

Steve Hill


Editor’s Note: The U.S. Transhumanist Party features this article by Steve Hill, originally published by our allies at the Life Extension Advocacy Foundation (LEAF) on January 7, 2019. This article presents the results of a human pilot study that involved the consumption of two promising senolytic drugs, dasatinib and quercetin, to target idiopathic pulmonary fibrosis. The results are promising and constitute a great step forward for senolytics being tested in human clinical trials. Another promising approach is the TAME trial, which is a double-blind randomized controlled clinical trial, to test if Metformin can treat various age-related diseases. 

~Bobby Ridge, Assistant Editor, July 4, 2019

The results from a human pilot study that focused on treating idiopathic pulmonary fibrosis with senescent cell-clearing drugs has been published. The drugs target aged and damaged cells, which are thought to be a reason we age and get sick, and remove them from the body.

Senescent cells and aging

As we age, increasing numbers of our cells become dysfunctional, entering into a state known as senescence. Senescent cells no longer divide or support the tissues and organs of which they are part; instead, they secrete a range of harmful inflammatory chemical signals, which are collectively known as the senescence-associated secretory phenotype (SASP).

Dr. Judith Campisi from the Buck Institute for Research on Aging, along with her research team, identified that senescent cells secreted the various harmful chemicals that characterize the SASP in 2008, which was when interest in senescent cells really began [1]. In 2010, building on this initial research, Dr. Campisi went on to show the link between the SASP and cancer [2].The SASP increases inflammation, harms tissue repair and function, causes the immune system to malfunction, and raises the risk of developing age-related diseases such as cancer. It can also encourage other nearby healthy cells to become senescent via the so-called bystander effect. Therefore, a small number of these cells can cause a great deal of harm.

Normally, senescent cells destroy themselves by a self-destruct process known as apoptosis before being cleared away by the immune system. Unfortunately, as we age, the immune system becomes weaker, and senescent cells start to build up in the body. The accumulation of senescent cells is considered to be one of the reasons why we age and develop age-related diseases.

It has been suggested that the clearance of senescent cells might help address a number of age-related diseases at once, as senescent cells are thought to be one of the fundamental reasons that we age. Drugs that can remove these unwanted, damaged cells are known as senolytics.

Human trial results for senolytics

This new publication by researchers at the Mayo Clinic, including James Kirkland, one of the pioneers of senolytic drugs, shows the results of a pilot study that uses dasatinib and quercetin to treat idiopathic pulmonary fibrosis [3].

Pulmonary fibrosis causes scarring of the lung tissue, which leads to the progressive loss of lung function over time. When the disease’s origin is unknown, it is called idiopathic pulmonary fibrosis, or IPF. The treatment options for this disease are extremely limited with no currently known cure.

The researchers in this new study tested a combination of dasatinib and quercetin, one of the earliest senolytic drug combinations that was tested in mice and shown to have beneficial results, particularly for the cardiovascular system [4-5]. It was also shown in a previous study that clearing senescent cells using dasatinib plus quercetin was able to alleviate idiopathic pulmonary fibrosis (IPF)-related dysfunction in a mouse model of the disease.

Fourteen patients with IPF were recruited for this pilot study, and the initial results, while leaving room for improvement, are promising.

Physical function evaluated as 6-min walk distance, 4-m gait speed, and chair-stands time was significantly and clinically-meaningfully improved (p < .05). Pulmonary function, clinical chemistries, frailty index (FI-LAB), and reported health were unchanged. DQ effects on circulating SASP factors were inconclusive, but correlations were observed between change in function and change in SASP-related matrix-remodeling proteins, microRNAs, and pro-inflammatory cytokines (23/48 markers r ≥ 0.50).

It should be noted that this was only a small pilot study and that the optimal human dosage and frequency is yet to be established. Typically, the next step is to launch a larger-scale study to establish this dosage.

The researchers also note that these results warrant evaluation of dasatinib plus quercetin in larger, randomized, and controlled trials for senescence-related diseases. In other words, they would like to test senolytics in larger studies for various age-related diseases, and the results certainly support doing exactly that.

Conclusion

These initial results are positive, despite there being plenty of room for improvement. The combination of these two drugs also appears to favor particular cell and tissue types over others, much like other senolytic drugs, which were discovered after dasatinib and quercetin were originally shown to clear senescent cells. It may be that a combination of different senolytics will be needed as a “cocktail” of sorts to fully clear out all the unwanted senescent cells, as different senescent cells appear to use various survival pathways to evade apoptosis, and no single drug can target them all.

We greet these early results positively and look forward to the beginning of larger-scale studies for multiple age-related diseases. Given how senescent cells appear to be implicated in most if not all age-related diseases, there are some exciting possibilities ahead.

Literature

[1] Coppé, J. P., Patil, C. K., Rodier, F., Sun, Y., Muñoz, D. P., Goldstein, J., … & Campisi, J. (2008). Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor. PLoS biology, 6(12), e301.

[2] Coppé, J. P., Desprez, P. Y., Krtolica, A., & Campisi, J. (2010). The senescence-associated secretory phenotype: the dark side of tumor suppression. Annual Review of Pathological Mechanical Disease, 5, 99-118.

[3] Nambiar, A., Justice, J., Pascual, R., Tchkonia, T., Lebrasseur, N., Kirkland, J., … & Kritchevsky, S. (2018). Targeting pro-inflammatory cells in idiopathic pulmonary fibrosis: an open-label pilot study of dasatinib and quercitin. Chest, 154(4), 395A-396A.

[4] Zhu, Y., Tchkonia, T., Pirtskhalava, T., Gower, A. C., Ding, H., Giorgadze, N., … & O’hara, S. P. (2015). The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs. Aging cell, 14(4), 644-658.

[5] Roos, C. M., Zhang, B., Palmer, A. K., Ogrodnik, M. B., Pirtskhalava, T., Thalji, N. M., … & Zhu, Y. (2016). Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice. Aging cell.[/column]

Steve Hill serves on the LEAF Board of Directors and is the Editor-in-Chief, coordinating the daily news articles and social media content of the organization. He is an active journalist in the aging research and biotechnology field and has to date written over 500 articles on the topic as well as attending various medical industry conferences. In 2019 he was listed in the top 100 journalists covering biomedicine and longevity research in the industry report – Top-100 Journalists covering advanced biomedicine and longevity created by the Aging Analytics Agency. His work has been featured in H+ Magazine, Psychology Today, Singularity Weblog, Standpoint Magazine, Keep Me Prime, and New Economy Magazine. Steve has a background in project management and administration which has helped him to build a united team for effective fundraising and content creation, while his additional knowledge of biology and statistical data analysis allows him to carefully assess and coordinate the scientific groups involved in the project. In 2015 he led the Major Mouse Testing Program (MMTP) for the International Longevity Alliance and in 2016 helped the team of the SENS Research Foundation to reach their goal for the OncoSENS campaign for cancer research.

 

Alzheimer’s Disease Reversed by Editing a Single Gene – Article by Steve Hill

Alzheimer’s Disease Reversed by Editing a Single Gene – Article by Steve Hill

Steve Hill


Editor’s Note: The U.S. Transhumanist Party features this article by our guest Steve Hill, originally published by our allies at the Life Extension Advocacy Foundation (LEAF) on April 13, 2018. In this article, Mr. Hill reviews a new study published in Nature that supports the idea that Alzheimer’s disease research efforts should target the ApoE4 gene, and not consider the ApoE3 gene as much, even though  previous research that focused on the ApoE3 gene cured Alzheimer’s disease in mice models. This is a promising step forward for Alzheimer’s research.

~Bobby Ridge, Assistant Editor, July 2, 2019

Researchers at Gladstone Institutes in San Francisco report that a gene variant associated with Alzheimer’s works differently in mice and humans, and they also demonstrate how modifying this gene could potentially prevent the plaques associated with Alzheimer’s from forming and damaging the brain. The new study was published in the journal Nature in January 2018 [1].

An ApoE3 gene variant is associated with Alzheimer’s disease

The gene apolipoprotein E3 (ApoE3) has a variant known as ApoE4, which is associated with the development and progress of Alzheimer’s disease. People with just one copy of the ApoE4 gene are at twice the risk as people without this gene variant. Some people even have two copies of the ApoE4 gene, which makes their risk of Alzheimer’s a staggering twelve times greater.

Both the ApoE genes produce their own forms of ApoE protein, which differ in structure. The ApoE4 protein is fragile and fragments because it cannot function in the same way as the regular ApoE3 protein in human nerve cells. These fragmented protein pieces are associated with the increased production of amyloid-β peptides and tau phosphorylation that are typical of Alzheimer’s disease.

The researchers wanted to find out how ApoE4 is linked to Alzheimer’s disease. They considered the possibility that the increased amyloid-β and tau phosphorylation from the fragmentation of ApoE4 drives disease progression. Another possibility involved the negative consequences of a lack of ApoE3 proteins, as they were replaced by the ApoE4 variant. The team also considered a combination of both of these possibilities.

The team investigated these potential answers by examining the effects of ApoE3 and ApoE4 on human nerve cells. Neurons were created by using pluripotent stem cells taken from volunteers who had either two copies of ApoE3 or two copies of the ApoE4 gene, and the researchers programmed these cells to become the desired type of neuronal cell.

The team compared the ApoE3 and ApoE4 neurons against neurons that were unable to produce either type of the ApoE protein. They discovered that neurons that produced no ApoE protein worked the same as those that produced ApoE3. This confirmed that it was not a lack of ApoE3 causing the problem but that ApoE4 protein alone was linked to Alzheimer’s disease.

This finding also sheds light on why treatments for Alzheimer’s that work in mice fail to translate to humans. The production of amyloid-β in mice is not influenced by ApoE4; this means that treatments that prove effective in mice may not work in humans, as the mouse models of the disease do not emulate the ApoE4-related form of Alzheimer’s that humans get. However, therapies that focus on reducing amyloid-β have worked in mice [2], so while ApoE4 functions differently in mice and humans, this is not the full story of Alzheimer’s. This research does, however, clearly show a way in which mouse models differ from humans, helping to guide future research.

Converting ApoE4 to ApoE3

The results of the study suggest that therapies that seek to modify the ApoE4 gene protein before it fragments might be a way to combat Alzheimer’s. This is how traditional medicine would generally approach the problem, treating the symptoms and not the cause.

However, the researchers took this one step further to a far more robust solution. Rather than simply attempting to treat the consequences of having an ApoE4 gene producing sub-par proteins, they completely removed the problem by using gene therapy to edit the genes and convert them from ApoE4 to ApoE3.

The converted genes ceased to produce the unstable ApoE4 protein and produced the stable ApoE3 version of it instead. This served to correct the problem at the root rather than trying to slap a band-aid on the consequences.

Conclusion

With so many failures to combat Alzheimer’s disease, it is easy to become disillusioned. We have seen mice cured of the disease numerous times, but these cures have failed to translate to humans. These new findings help to progress knowledge in the field and offer potential new ways to defeat Alzheimer’s.

What is refreshing about this study is how the researchers have opted to attack the problem at the root cause: the production of misfolded proteins that lead to the progression of the disease. It is becoming ever more clear that if we are going to make progress on ending age-related diseases, we must target the aging processes themselves, which cause these diseases.

Literature

[1] Yuang, Y. et al. (2018) Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector. Nature Medicine doi:10.1038/s41591-018-0004-z

[2] Hu, X., Das, B., Hou, H., He, W., & Yan, R. (2018). BACE1 deletion in the adult mouse reverses preformed amyloid deposition and improves cognitive functions. Journal of Experimental Medicine, jem-20171831.

Steve Hill serves on the LEAF Board of Directors and is the Editor in Chief, coordinating the daily news articles and social media content of the organization. He is an active journalist in the aging research and biotechnology field and has to date written over 500 articles on the topic as well as attending various medical industry conferences. In 2019 he was listed in the top 100 journalists covering biomedicine and longevity research in the industry report – Top-100 Journalists covering advanced biomedicine and longevity created by the Aging Analytics Agency. His work has been featured in H+ Magazine, Psychology Today, Singularity Weblog, Standpoint Magazine, Keep Me Prime, and New Economy Magazine. Steve has a background in project management and administration which has helped him to build a united team for effective fundraising and content creation, while his additional knowledge of biology and statistical data analysis allows him to carefully assess and coordinate the scientific groups involved in the project. In 2015 he led the Major Mouse Testing Program (MMTP) for the International Longevity Alliance and in 2016 helped the team of the SENS Research Foundation to reach their goal for the OncoSENS campaign for cancer research.

Dr. Nichola Conlon and James Strole Discuss the Biggest Reported Increase of NAD in Humans

Dr. Nichola Conlon and James Strole Discuss the Biggest Reported Increase of NAD in Humans

Nichola Conlon
James Strole


Dr. Nichola Conlon, Nuchido CEO & Co-founder, spoke with James Strole, Director of the Coalition for Radical Life Extension, about what she’s bringing to RAADfest 2019:
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Increasing NAD+ levels to a level comparable with people 17 years younger. 
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NAD is a natural molecule found within every living cell of your body. Without it, your body couldn’t generate the energy it needs to survive or kick-start its natural cell maintenance and repair systems. In its youthful state, your body naturally makes and retains high levels of NAD. But as you age, these levels are not maintained and the amount of NAD in your body drops by 50% every 20 years. This decline has been scientifically linked to the increasing effects of aging.
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Recent scientific breakthroughs have shown that one of the best ways to combat aging is to maintain high levels of NAD.
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Nuchido has pioneered the use of systems pharmacology and clinical research to boost and maintain NAD. In a scientific world-first, the team achieved the biggest increase of NAD in humans reported by any scientific group.
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Hear what she has to share, and meet her at RAADfest 2019, October 3-6:

To find out more and register, visit the RAAD Fest website at https://www.raadfest.com/.


Watch the U.S. Transhumanist Party’s prior appearances at RAAD Fests in 2017 and 2018 below.

RAAD Fest 2017

The U.S. Transhumanist Party – Pursuing a Peaceful Political Revolution for Longevity – August 11, 2017

Advocating for the Future – Panel at RAAD Fest 2017 – Gennady Stolyarov II, Zoltan Istvan, Max More, Ben Goertzel,

RAAD Fest 2018

The U.S. Transhumanist Party: Four Years of Advocating for the Future – Gennady Stolyarov II at RAAD Fest 2018 – September 21, 2018

Gennady Stolyarov II Interviews Ray Kurzweil at RAAD Fest 2018 – September 21, 2018

U.S. Transhumanist Party Meeting at RAAD Fest 2018 – September 22, 2018

Andrés Grases Interviews Gennady Stolyarov II on Transhumanism and the Transition to the Next Technological Era – September 23, 2018

Register for RAAD Fest 2019 here

SVAI Undiagnosed-1 Collaborative Genomics Research Case: A Call for Bioinformatics and/or Computational Biology Researchers to Get Involved

SVAI Undiagnosed-1 Collaborative Genomics Research Case: A Call for Bioinformatics and/or Computational Biology Researchers to Get Involved

SVAI


Editor’s Note: The U.S. Transhumanist Party / Transhuman Party provides this announcement to encourage any of our members and allies with expertise in bioinformatics and/or computational biology to contribute their talents to resolving the medical conundrum of one of our longtime loyal members, John – referred to in the Patient Case Background below as JCM – who has suffered from an undiagnosed condition his entire life. The Undiagnosed-1 Collaborative Genomics Research Case, arranged by the non-profit, volunteer-run organization SVAI, will take place on June 7-9 in San Francisco.  Find out more about this effort at breakthrough medical diagnosis – which could make a lifetime’s worth of difference to John – here. Even if you cannot attend the event in person, you can apply to participate in the research online here. John has generously provided for his data to be made available in an open-source manner so that future researchers into rare diseases could benefit from it and advance the state of medical science. Researchers have already agreed to study the data; one of them, longtime life-extension advocate Kevin Perrott, the CEO and Founder of OpenCures, a company located at the Buck Institute for Research on Aging that helps individuals performing self-directed research to access technologies and education, wishes to use mass spectrometry-based metabolomics and proteomics to find biomarkers of aging, and John has agreed to be a part of that project. John’s quest to discover the causes of his own ailment can thus lead to beneficial insights that could be used to research ways the extend the lifespans of all. The U.S. Transhumanist Party / Transhuman Party fully supports this noble effort and is heartened that many prominent researchers have already stepped forward to participate. However, there can never be enough trained and talented minds working on such endeavors, so, if you have the relevant expertise, we strongly encourage you to get involved.

~ Gennady Stolyarov II, Chairman, United States Transhumanist Party / Transhuman Party, May 21, 2019


PATIENT CASE BACKGROUND

  1. Our patient, JCM, is a 33-year-old Caucasian male suffering from undiagnosed disease(s).
  2. As an infant, the patient, JCM reports a history of vomiting after breastfeeding and Failure to Thrive (FTT).
  3. Since childhood, JCM has had a significant issue in weight gaining despite adequate caloric intake, though his height has remained on the curve. As a child, he also has reported nausea, stomach aches and an overall aversion to food.
  4. In his 20’s, JCM’s GI issues became more severe as he began to have daily lower abdominal pain characterized by burning and nausea. He began to develop chronic vomiting daily and would vomit as many as 5 times per day.
  5. At his current age, JCM is 5’10” tall and weighs 109lbs. He is easily fatigued due to his limited muscle mass and low weight.
  6. He reports several issues: pain and weakness in his knees, a couple of disc herniations, and shoulder dislocations. His GI issues and pain prevents him from attempts on building muscle masses with lifting and protein intake.

Learn more about the Undiagnosed-1 Collaborative Genomics Research Case here. You are encouraged to share this information with others who may be interested and qualified to assist.