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Anti-Aging Gene Therapy for Dogs Coming This Fall – Article by Steve Hill

Anti-Aging Gene Therapy for Dogs Coming This Fall – Article by Steve Hill

Steve Hill


Editor’s Note: The U.S. Transhumanist Party features this article by Steve Hill of the Life Extension Advocacy Foundation (LEAF) originally published on the LEAF site on May 8th, 2019.  The article brings attention to a new program that aligns with our mission of ending age-related diseases, which the U.S. Transhumanist Party supports as part of our policy goals.

~ Brent Reitze, Director of Publication, United States Transhumanist Party, May 10th, 2019


In an article last May, we covered how Rejuvenate Bio, a startup biotech company led by Professor George Church, was planning to reverse aging in dogs as a step towards bringing these therapies to us. Those plans are now starting to move forward with news of a trial launch in the fall later this year.

Developing anti-aging therapies in dogs is the first step

Back in 2015, the Church lab at Harvard began testing a variety of therapies focused on age reversal using CRISPR, a gene editing system that was much easier and faster to use than older techniques. Since then, Professor Church and his lab have conducted a myriad of experiments and gathered lots of data with which to plan future strategies for tackling aging.

Last year, we learned that Rejuvenate Bio had already conducted some initial studies with beagles and were planning to reverse aging using CRISPR gene therapy. The goal was to move these studies forward to a larger scale as a step towards bringing similar therapies to humans to prevent age-related diseases. Professor Church was so confident that his team would find a solution, he even suggested that he may be one of the first human volunteers once therapies finally reach people.

“Dogs are a market in and of themselves,” Church said during the 2018 Radical Wellness event in Boston. “It’s not just a big organism close to humans. It’s something that people will pay for, and the FDA process is much faster. We’ll do dog trials, and that’ll be a product, and that’ll pay for scaling up in human trials.”

Choosing to develop therapies for dogs helps pave the way for therapies that address the aging processes in humans and could support their approval, which would otherwise be much more challenging. Currently, if you were to tell the FDA that you want to increase lifespan in humans by 20 years, you would need to come back in 20-30 years with the data, which just isn’t practical.

However, if Rejuvenate Bio can produce robust data in dogs showing that some processes of aging have been reversed, it lends considerable justification for human trials. The company is also taking a different tack; instead of focusing on increasing lifespan, it is instead targeting an age-related disease common in dogs, which should be cured if age reversal occurs.

This is based on the concept that in order to treat age-related diseases and cure them, you need to target the root causes of those diseases, which are the underlying aging processes themselves. If Rejuvenate Bio is successful, this would lend additional supporting evidence that directly treating aging to prevent age-related diseases could also work in humans.

Gene therapy trial for mitral valve disease

Rejuvenate Bio has now announced that it will be launching a gene therapy trial in dogs during the fall this year to combat mitral valve disease (MVD), a condition commonly encountered in the Cavalier King Charles Spaniel breed and directly caused by the aging processes. The study will initially focus on this particular breed and expand to include other dogs with MVD as time passes.

We are developing a novel cardio-protective gene therapy to stop the progression of heart failure in dogs. As a part of the technical development, we will launch a study in dogs with Mitral Valve Disease (MVD) in the fall of 2019. This study will provide valuable information that will aid our effort to address MVD.

MVD is due to the failure of the mitral valve in the heart, a one-way valve between the two chambers of the heart that prevents the backflow of blood as it is pumped around the body. As aging occurs, the mitral valve can degenerate, which allows backflow to occur, leading to left atrial chamber enlargement, congestive heart failure, and, ultimately, death.

This gene therapy is focused on adding a new piece of DNA into the cells of the dogs in order to halt the buildup of fibrotic scar tissue in the heart, which is linked to the progression of MVD and other forms of heart failure. Fibrotic tissue is the result of imperfect repair, which occurs when a more complete repair is not possible due to a lack of replacement cells or high levels of inflammation.

The researchers are keen to point out that this new piece of DNA is not passed onto the offspring of the animal and cannot transfer between dogs. This is because the therapy does not alter the DNA in the germline cells, the cells that are involved in reproduction and passing on genetics to an organism’s offspring.

If you wish to enroll your Cavalier King Charles Spaniel in the trial coming this fall, then register your interest with Rejuvenate Bio to learn more about eligibility and how to apply.

Conclusion

This is a very exciting study and, as the company discusses on its project page, the therapy may also be useful for other heart conditions, such as dilated cardiomyopathy (DCM). If the initial results are successful, it would be highly likely that we could see more dog breeds included as well as other conditions, including DCM, added to the program.

We wish Professor Church and Rejuvenate Bio every success, as this forms the basis for potentially moving such therapies into human trials more quickly as well as potentially helping our furry friends to live longer, healthier lives as well. We love our pets, and it is only logical that we should want the same healthy and longer lives for them as we do for ourselves, and the process for them is the same for us: new medical innovations that target the aging processes directly in order to end age-related diseases.

About  Steve Hill

As a scientific writer and a devoted advocate of healthy longevity technologies, Steve has provided the community with multiple educational articles, interviews and podcasts, helping the general public to better understand aging and the means to modify its dynamics. His materials can be found at H+ Magazine, Longevity reporter, Psychology Today and Singularity Weblog. He is a co-author of the book “Aging Prevention for All” – a guide for the general public exploring evidence-based means to extend healthy life (in press).

About LIFE EXTENSION ADVOCACY FOUNDATION (LEAF)

In 2014, the Life Extension Advocacy Foundation was established as a 501(c)(3) non-profit organization dedicated to promoting increased healthy human lifespan through fiscally sponsoring longevity research projects and raising awareness regarding the societal benefits of life extension. In 2015 they launched Lifespan.io, the first nonprofit crowdfunding platform focused on the biomedical research of aging.

They believe that this will enable the general public to influence the pace of research directly. To date they have successfully supported four research projects aimed at investigating different processes of aging and developing therapies to treat age-related diseases.

The LEAF team organizes educational events, takes part in different public and scientific conferences, and actively engages with the public on social media in order to help disseminate this crucial information. They initiate public dialogue aimed at regulatory improvement in the fields related to rejuvenation biotechnology.

Supporting the SomosMiel Revolution: Time to Act – Article by David Wood

Supporting the SomosMiel Revolution: Time to Act – Article by David Wood

David Wood


Editor’s Note: The U.S. Transhumanist Party features this article by David Wood, Chair of the London Futurists and Secretary of Humanity+.  He argues in support of the Somos Miel party and their work in Spain, initiatives which are similar to work supported by the US Transhumanist Party in the United States. This article was originally posted on David Wood’s blog on April 24, 2019.

~ Brent Reitze, Director of Publication, United States Transhumanist Party, May 2nd, 2019


 

The most important changes often arise from the bold actions of outsiders.

Those of us who desire positive humanitarian change need to be flexible enough to recognise which outsiders can be the best vehicles for the transformations we want to see in society.

And we need to be ready to get behind these opportunities when they arise.

Consider the key example of the transformation of healthcare, towards a new focus on the reversal of aging as providing the best route to better health for everyone.

For those of us who hold that vision of the forthcoming “abolition of aging”, what are the most practical steps to make that vision a reality?

Here’s my answer. It’s time to get behind “Somos Miel”.

Futuristicamente

Miel is a recently formed political party, which is taking part in Spain in the elections on the 26th of May to the European Parliament.

The word “miel” has two meanings. First, it’s the Spanish for “honey”. Somos Miel means “We are honey”. The association of honey with improved health exists in many cultures around the world.

Second, MIEL is the abbreviation for “Movimiento Independiente Euro Latino”. Translating from Spanish to English gives: “The Independent Latin Euro Movement”.

Heading the party’s list of candidates is José Cordeiro, described as follows in the introduction of his Wikipedia article:

José Luis Cordeiro is an engineer, economist, futurist, and transhumanist, who has worked on different areas including economic development, international relations, Latin America, the European Union, monetary policy, comparison of constitutions, energy trends, cryonics, and longevity. Books he has authored include The Great TabooConstitutions Around the World: A Comparative View from Latin America, and (in Spanish) El Desafio Latinoamericano (“The Latin American challenge”) and La Muerte de la Muerte (“The death of death”).

Cordeiro was born in Caracas, Venezuela from Spanish parents who emigrated from Madrid during the Franco dictatorship…

He’s evidently a man of many talents. He’s by no means a European political insider, infused by the old ways of doing politics. Instead, he brings with him a welcome spread of bold outsider perspectives.

When asked if he is from “the right” or “the left”, his answer, instead, is that he is from “the future”. Indeed, he often appends the greeting “futuristicamente” after his name, meaning “Yours futuristically”.

José is also known as a vocal advocate for “revolution” – a revolution in the potential of humanity. He has the courage to advocate ideas that are presently unpopular – ideas that he believes will soon grow in public understanding and public support.

Working together

I first met José at the TransVision 2006 conference in Helsinki, Finland. I remember how he spoke with great passion about the positive possibilities of technology in the next stage in the evolution of life on the earth. As the abstract from that long-ago talk proclaims:

Since the Big Bang, the universe has been in constant evolution and continuous transformation. First there were physical and chemical processes, then biological evolution, and finally now technological evolution. As we begin to ride the wave into human redesign, the destination is still largely unknown but the opportunities are almost limitless.

Biological evolution continues but it is just too slow to achieve the goals now possible thanks to technological evolution. Natural selection with trial and error can now be substituted by technical selection with engineering design. Humanity’s monopoly as the only advanced sentient life form on the planet will soon come to an end, supplemented by a number of posthuman incarnations. Moreover, how we re-engineer ourselves could fundamentally change the ways in which our society functions, and raise crucial questions about our identities and moral status as human beings.

Since that first meeting, the two of us have collaborated on many projects. For example, we both sit on the board of directors of Humanity+. José has spoken on a number of occasions at the London Futurists events I organise – such as TransVision 2019 which will take place in London on 6-7 July. And we are named as co-authors of the Spanish language book La Muerte de la Muerte which has attained wide press coverage throughout Spain.

Another thing we have in common is that we are both impatient for change. We’re not content to sit back and watch impersonal forces operate in society at their own pace and following their own inner direction. We believe in doing more than cheering from the sidelines. We both believe that the actions of individuals, wisely targeted, can have a huge impact on human affairs. We both believe that inspired political action, at the right time, can unleash vast public resources in support of important transformational projects.

We also recognise that delays have major consequences. Each single day that passes without the widespread availability of reliable treatments for biological aging, upwards of 100,000 people die as a result of aging-related diseases. That’s 100,000 unnecessary human deaths, every single day – preceded in almost every case by extended suffering and heartache.

Moving faster

On a positive note, there is considerable good news to report, regarding progress with regenerative medicine and rejuvenation biotechnology. The Undoing Aging conference in Berlin last month contained an encouraging set of reports from a host of world-leading scientists working in this field. Keep an eye on the Undoing Aging channel in YouTube for videos from that event. For a review of the human implications of these scientific breakthroughs, the forthcoming RAADfest in Las Vegas in October will be well worth attending – to hear about “the most powerful information and inspiration for staying alive”.

But the opportunity exists for progress to go much faster, if more elements of society decide to put their weight behind this project.

That’s where Miel comes in. José is a well-known figure in Spain, due to his many media appearances there. Current indications are that he stands a fighting chance of being elected to the European Parliament. If elected, he’ll be a tireless public advocate for the cause of rejuvenation healthcare. He’ll promote studies of the economic implications of different scenarios for the treatment of aging. He’ll also champion the creation of a European Agency for Anti-Aging, to boost research on how addressing aging can have multiple positive benefits for the treatments of individual aging-related diseases, such as dementia, cancer, and heart failure.

You’ll find a number of articles on the Miel blog about these aspects of Miel policy. For example, see “Within 25 years, dying will be optional” and “I’m not afraid of artificial intelligence, I’m afraid of human stupidity”.

You’ll also observe from its website how Miel is, wisely, giving voice in Spain to a community that perceives itself to be under-represented, namely the Latin Americans – people like José himself, who was born in Venezuela. Those of us who aren’t Latin Americans should appreciate the potential for positive change that this political grouping can bring.

Time for action

Despite the groundswell of popular support that Miel is receiving, it’s still in the balance whether the party will indeed receive enough votes throughout Spain to gain at least one member in the European Parliament.

I’m told that what will make a big difference is an old-fashioned word: money.

If it receives more donations, Miel will be able to place more advertisements in social media (Facebook, YouTube, Instagram, etc). With its messages in front of more eyeballs, the chance increases of popular support at the ballot box.

In a better world, money would have a lower influence over politics. But whilst we should all aspire to move politics into that better state, we need to recognise the present reality. In that reality, donations have a big role to play.

To support Miel, visit the party’s donation page. Donations are accepted via credit cards, debit cards, or PayPal.

But please don’t delay. The elections are in just one month’s time. The time for action is now.

Interview of Dr. José Luis Cordeiro by Elena Milova

Interview of Dr. José Luis Cordeiro by Elena Milova

Elena Milova
José Luis Cordeiro


Editor’s Note: The U.S. Transhumanist Party features this interview of Dr. José Luis Cordeiro by Elena Milova at LeafScience.Org, originally published on their site on April 19, 2019.  Dr. Cordeiro is working to foster transhumanist-friendly political policies in Spain, a goal supported by the U.S. Transhumanist Party as part of our policy objectives.

~ Brent Reitze, Director of Publication, United States Transhumanist Party, May 1st, 2019


At Undoing Aging 2019, jointly organized by SENS Research Foundation and Forever Healthy Foundation, there was a session focused on the ways to make healthy life extension and medical progress a greater part of the global agenda. Among the speakers there was Jose Cordeiro, the vice chair of Humanity Plus, director of The Millennium Project, fellow of the World Academy of Art and Science, and board member of the Lifeboat Foundation.

Jose earned his Bachelor’s and Master’s degrees in Mechanical Engineering at the Massachusetts Institute of Technology (MIT) in Cambridge, Massachusetts. His thesis was focused on the modeling of the International Space Station. Jose has also studied International Economics and Comparative Politics at Georgetown University in Washington, D.C., and received his MBA in France at INSEAD, where he focused on Finance and Globalization.

Last year, Jose decided to begin his political activities in order to foster the development of rejuvenation biotechnologies in Spain and to work on the integration of Latin American immigrants into Spain’s aging society and thus maintain the country’s productivity. He kindly agreed to give me an interview to discuss more about his ambitious initiative.

Hello, Jose, thanks for taking the time to talk with us. You are currently beginning your campaign to win several seats in the European parliament. This is a very unusual situation, because it’s still rare that transhumanist ideas like significant life extension are part of a political agenda. Before we dig into your political program, I would really want to know more about you as a person and what kind of experiences led you to becoming a transhumanist in the first place. Please tell us a few things about your childhood; what life events or books helped you to develop the vision that you have right now?

My family is from Spain. During the dictatorship of Francisco Franco, this country became very poor, and that pushed my family to consider moving to Venezuela. At the time, Venezuela was a prosperous country, so we had moved, and I grew up there. When I was a little child, there was no color TV; it was black and white back then. I remember that the first transmission in color was the moon landing of the Apollo mission. I was so fascinated by the idea that man had gone to the moon and also by the color picture, even though the moon was mostly gray. That sparked my interest in science fiction. My mother gave me books by Jules Verne. To me, he was an idol; I loved his writing. Then, there were other writers, like Isaac Asimov and Sir Arthur C. Clarke, who helped me develop my imagination.

When I was older, I even went to meet Sir Arthur C. Clarke in Colombo, Sri Lanka. It turned out that he had a scuba diving center in Indonesia. You see, he believed that going into outer space and going into the ocean were the ultimate experiences and that they both showed how weak our bodies were. To me, it was one more piece of proof that we really need technology to survive in outer space or in the oceans. I had an opportunity to invite him to talk at the transhumanist conference that I had organized. That was really beautiful.

Speaking of the other books, I also read Robert Heinlein’s books on Mars, and all of this combined really made me go into engineering. I decided to go to MIT, the Massachusetts Institute of Technology, and I majored in engineering in order to be able to participate in all these fascinating projects of mankind in space. I have been very lucky to have four Nobel laureates among my teachers, and I’ve been always following future trends. Since that time, I read the books of the Club of Rome and the World Future Society. There were many magazines about science, such as Popular Mechanics, Computer World, and others. Then, I learned about Extropians and the World Transhumanist Association when it was being created, and I learned a lot from this community, too.

I lived three years in Japan and four years in California. Then, I met Ray Kurzweil at MIT, as he was one of its board members. He’s a fantastic person, and I read all his books, the Age of intelligent machines was the first one, and then in 1998-99, he published the Age of Spiritual Machines, where he makes all his forecasts of the future.

It seems to me that there is still a huge gap between technology, which involves developing all sorts of machines and engineering, and life sciences, rejuvenation research, and life extension. What were your ideas or some events in your life that actually made you look into this direction as well?

Because of my science fiction reading and my training at MIT, I have been very much a technologist, futurist, and transhumanist. Like Ray Kurzweil, I believe that we will transcend the biological condition and move into a post-biological condition. Arthur C. Clarke said that we are carbon-based bipeds and that we should actually evolve and transcend.

I was not particularly interested in longevity and rejuvenation technologies until 1999-2000, when a friend of mine died. Also, sadly, my father died in 2013, and that really affected my life and my views. I was living in California back when the humanitarian crisis in Venezuela had happened. My father died of something that no one dies of today, which is a lack of access to dialysis. The crisis was so bad that there were no medical services, no food, no clean water, no electricity, no gasoline in the country with the largest oil reserves on the planet. My family had to witness how a bad government can destroy a country and put a whole nation into misery. I consider myself lucky that I managed to take my mother from Venezuela back to Spain, and I am so happy that she is alive. Then I decided to stay in Spain and work internationally.

I am traveling around the globe, as I am giving lectures at major universities in many countries. As you know, I teach in two universities in Moscow: in the MIPT and in the Higher School of Economics. I also teach in universities in Japan and in Korea, focusing on several main topics that are important for shaping the global agenda in a reasonable way. In the Higher School of Economics, I talk about technologies, because economists need to know about emerging technologies, while the MIPT is just the opposite; I talk more about the future of economics, the world moving from scarcity to abundance, and how technology can help with that. I talk about energy, about the necessity to switch from fossil fuels to renewables. Actually, I coined the word ‘energularity’: it’s an unlimited amount of energy that we can use for our needs. I talk about longevity, rejuvenation, regenerative medicine, the possibility to control aging and remain healthy for as long as we want. I am teaching the young generation of leaders how to build the future of global prosperity, and I decided to bring my knowledge and my vision to the political arena, too.

Could you please tell our readers about the pillars of your political program? What are the specific goals that you are going to focus on?

Two main things that I plan to focus on are the healthy longevity of the Spanish population and the integration of immigrants from Latin America. Let me explain why I consider these two topics extremely important and how they are intertwined.

Spain, as you know, is one of the countries with the highest life expectancy in the world. Our people live very long. However, this also means that our population is aging; there is a large and fast-growing share of people who are 65 years old and older, which is now over 20%, and these people have age-related chronic diseases. The medicine of the 20th century cannot restore health, and there are many age-related diseases that remain incurable, causing enormous amount of human suffering. However, it was recently proven in animal studies that by directly targeting the processes of aging, the root causes of aging, we could learn how to cure these diseases, reverse aging, and ensure better health and productivity in later life. If we support scientific research on the mechanisms of aging, we can develop cures for people very soon; in the next 10 years, there will already be several therapies of a new type that will be able to slow down and even partially reverse aging.

United Nations Department of Economic and Social Affairs/Population Division World Population Prospects: The 2017 Revision, Volume II: Demographic Profiles

So, healthy longevity for the Spanish population is my primary focal point. I have three very clear targets. The first is the creation of the European Institute on Aging to work on the problem of aging and on the latest rejuvenation biotechnologies and to put together all the knowledge in different areas and different countries to give our aging society innovative treatments as soon as possible.

The second target is the development of more flexible regulations. I actually like to say that Americans invent things, the Chinese or the Japanese improve things, and the Europeans regulate. Sadly, there is overregulation all over Europe. Let me give you an example. In Japan, if you have already done phase two of human clinical trials, which means that you have already proven that the treatment is safe and it works, even if the experimental group in phase two is not large, a patient can get those treatments, especially if the patient is in critical condition, or, even worse, terminal condition. People in Japan have a chance to use the innovation and a chance to overcome the disease. You can do that in Japan but not in Europe, despite the fact that the pace of population aging in Japan and in Europe is the same; we have many old people around.

The third target is an increase in the science and technology budget of the European Union. For the next framework program, which is called Horizon Europe, beginning in 2021, the budget is expected to increase to 100 billion euros, but I think it should be increased even more, to 120 billion. The projects sponsored by Horizon Europe should be more also focused on regenerative biotechnologies in order to cope with the massive population aging and population decline.

So, you would like to contribute to the creation of a coordination center on aging research, appropriate funding for this research, and on regulatory improvement in order to ensure that the emerging rejuvenation biotechnologies can be available as soon as possible?

That is right, and I have done a great deal preparing the ground for these improvements. As you know, as a proponent of healthy life extension, I have organized many scientific conferences in Spain, and I have invited international luminaries from the field of aging research, such as Dr. Aubrey de Grey, who was the first to recognize the mechanisms of aging as new therapeutic targets.

I have always tried to spread the word about the work of our brilliant Spanish scientists, and I have also written several books on this topic to educate the public on this matter and to allow more people to benefit from the development of rejuvenation technologies; the last one of my 13 books is currently a bestseller in Spain called La Muerte De La Muerte (The Death of Death).

Yes, I have seen it – are you planning to have it translated into other languages?

Yes, it is coming out now in Portuguese, then in Korean, and then in other languages. I hope that there will also be English and Russian translations soon enough.

However, this is only one part of my program. The other one is based on the other pressing issues of Spain. You have heard the motto of my campaign, #SomosMIEL – MIEL stands for ‘Movimiento Independiente EuroLatino’ (the Independent EuroLatino Movement).  Because of the crisis in Latin America, and especially Venezuela, Spain has become a home for many immigrants; around 10% of the Spanish population are immigrants. Think about it. The native Spanish population is aging, our population is declining, and our workforce is shrinking. The immigrants are people with a similar cultural and religious background, who speak Spanish perfectly, and who have a good education and could contribute to the development of the country much better if we removed certain barriers and restrictions.

First, I think we need to eliminate the Schengen visa for people in Ecuador, the Dominican Republic and Bolivia, at least in the case of family reunification. Next, I would focus on extending the approved period of being an independent worker from one to five years. The third target is to contribute to the homologation of titles and degrees in education. When all these immigrants come, even though we speak the same language, their degrees are not accepted. There is already a good precedent of solving this problem in Europe with the Bologna Declaration, the agreement that allows homologation of all titles in Europe. However, now we have to take this to the international level and certainly with Latin America.

There is one more question that I plan to work on: the recognition of Spanish as one of the official languages of the European Union. Spanish is the second most frequently spoken language in the world after Chinese. It is not even recognized in the European Union, which has only three official working languages: English, French, and German.

As we are moving towards a world that is more and more strongly connected, I think it makes perfect sense to facilitate communication and exchange of valuable knowledge and experience between the major regions, such as Spain, the European Union, Latin America, and the United States. There are 50 million Spanish speakers in the United States.

So, technically, what you’re trying to achieve with your program is to remove the barriers that prevent Spanish-speaking society from acting as a whole. One example is the integration of immigrants from Latin America, and the other one is the improvement of cross-border communication by making Spanish an official language of the European Union. I find that fascinating. Because, as we all know, there are these global challenges that we’re dealing with, like climate change, pollution, lack of renewable energy, and population aging, and they require global cooperation. The barriers become increasingly unwelcome, I would say, because these problems just cannot be solved at the level of one country. I find it a very valuable social experiment.

Yeah, that’s a beautiful way to put it. However, we have a long way to go. We live in a world of abundance that is full of opportunities brought to us by technological progress, and it is quite disappointing that we still have poverty, we still have suffering from aging, and we still find ourselves witnessing humanitarian crises like the one in Venezuela that killed my father. Five million Venezuelans have been forced to leave the country, five million. This is not a small number, and we still don’t know how to deal with it in a way that these people can have the decent lives that they deserve. We need to learn how to not leave anyone behind. We have to become more compassionate. This could happen to any country, like it happened to Germany during Hitler’s government. We have to collaborate to make sure that we will not make the same mistakes ever again. We live at the borderline between a fantastic positive future and a horrible, terrible past, and we have to move forward, positively contribute to it, and create a better society, a better world for everybody.

What insights would you like to share with our readers?

Life is so beautiful; it is a fantastic gift. I think everybody should enjoy life, should have a chance to improve and extend life and to do more things. I speak five languages, and I’d want to speak ten if I had the time. I have been to 137 countries, and I would like to go to two hundred more. I would like to write and read more books, watch many movies, and listen to so much more music, and there is no time. Time is so valuable. Ask yourself, who could you become if you had another century of healthy life? Therefore, we need more lifetime so that we can enjoy more, develop and reinvent ourselves to become better people, and make this world a better place. Going into politics for me is my reinvention. I think that I have enough experience to take all these fascinating academic findings and ideas professionally into politics and to make a difference. That is my mission: to bring healthy longevity and profound social integration to Spain. Wish me luck.

The 2020 Undoing Aging Conference Will Take Place May 21 to 23 in Berlin, Germany – Announcement by Undoing Aging

The 2020 Undoing Aging Conference Will Take Place May 21 to 23 in Berlin, Germany – Announcement by Undoing Aging

Undoing Aging


Editor’s Note: The U.S. Transhumanist Party features this announcement by the Undoing Aging Conference, a joint project between the SENS Foundation and the Forever Healthy Foundation,  originally published on their site on April 2, 2019.  The Undoing Aging Conference is focused on the cellular and molecular repair of age-related damage as the basis of therapies to bring aging under full medical control. Undoing Aging 2020 will once again bring together scientists and startups from around the globe, all pioneers in their respective fields, who are leading the charge in maintaining and restoring full health in old age. Such research is supported by the U.S. Transhumanist Party as part of our policy goals.

~ Brent Reitze, Applicant for Director of Publication, United States Transhumanist Party, April 4, 2019


April 2, 2019  Mountain View, California / Berlin, Germany

After the incredible success of the 2019 Undoing Aging Conference, SENS Research Foundation and Forever Healthy Foundation are pleased to announce Undoing Aging 2020, which will take place on May 21 – 23. As UA2019 was sold out with nearly 500 participants from over 30 countries, Undoing Aging 2020 will be moving to a larger venue.

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The Undoing Aging Conference is focused on the cellular and molecular repair of age-related damage as the basis of therapies to bring aging under full medical control.  Among the 40 brilliant speakers at Undoing Aging 2019, there were giants in regenerative medicine such as: Dr. Nir Barzilai, Dr. Jerry Shay, Dr. Evan Snyder, Dr. Judith Campisi, and many more. Undoing Aging 2020 will once again bring together scientists and startups from around the globe, all pioneers in their respective fields, who are leading the charge in maintaining and restoring full health in old age. To accommodate the exciting growth of the emerging rejuvenation biotechnology industry, Undoing Aging 2020 will add a dedicated forum and exhibition space for rejuvenation biotech companies to present themselves to prospective investors and industry partners.

Additionally, the 2020 conference will add a special “Rejuvenation Now” session highlighting the first generation of human rejuvenation therapies that are either currently in clinical trials or are available today.

Undoing Aging 2020 is not only open to the scientific community, but also welcomes startups, investors, the general media, and all interested members of the broader rejuvenation movement. The conference will feature a student poster session showing the work of innovative undergraduate and graduate students in the field of damage repair.

“The accelerating rate of progress in rejuvenation research is now unmistakeable at all levels: publications, transfer into rapidly-funded startup companies, and even into the clinic. One marker of this is the worldwide proliferation of conferences focused on it. But I have no doubt that Undoing Aging will maintain its pre-eminence among them, with its strong focus on the most cutting-edge science, its long history dating back to my first Cambridge conference in 2003, and above all its steadfast support from Forever Healthy,” said Dr. Aubrey de Grey, CSO of SENS Research Foundation.

“We are very excited to work with SENS on Undoing Aging,” stated Michael Greve, founder, and CEO of the Forever Healthy Foundation. “Forever Healthy has two key goals for this conference: To support the remarkable scientific community and the rejuvenation biotechnology startups already working on repair of age-related damage and to create an unique opportunity to experience that bringing aging under complete, genuine medical control is realistic, achievable, and, indeed, beginning to happen.“


About Forever Healthy Foundation
Forever Healthy is a private, non-profit initiative with the mission to enable people to vastly extend their healthy lifespan and be part of the first generation to cure aging.

Thru its ‘Rejuvenation Now‘ and ‘Maximizing Health‘ initiatives, Forever Healthy seeks to continuously identify and evaluate new rejuvenation therapies on risks, benefits, and potential application and to harness the enormous wealth of the world’s cutting-edge medical knowledge to empower informed decisions about health and well-being.

In addition, Forever Healthy supports the development of rejuvenation therapies that undo the damage of aging by funding basic research, bringing together the world’s leading scientists at the Undoing Aging conference and supporting startups that work on actual therapies for human use. For more information, please visit forever-healthy.org

About SENS Research Foundation
SENS Research Foundation is a 501(c) nonprofit that works to research, develop and promote comprehensive regenerative medicine solutions for the diseases of aging. The foundation is focused on a damage-repair paradigm for treating the diseases of aging, which it advances through scientific research, advocacy, and education.

SENS Research Foundation supports research projects at universities and institutes around the world with the goal of curing such age-related diseases as heart disease, cancer, and Alzheimer’s disease. Educating the public and training researchers to support a growing regenerative medicine field are also significant endeavors of the organization that are being accomplished through advocacy campaigns and educational programs. For more information, please visit sens.org

To stay updated on Undoing Aging, you can follow their facebook page.

Announcing the Longevity Book Club for Lifespan Heroes – Announcement by Javier Noris

Announcing the Longevity Book Club for Lifespan Heroes – Announcement by Javier Noris

Javier Noris


Editor’s Note: The U.S. Transhumanist Party features this announcement by our cohorts at the Life Extension Advocacy Foundation, originally published on their site on March 19, 2019.  The program helps bring attention to published works promoting the mission of ending age-related diseases, a mission the U.S. Transhumanist Party supports as part of our policy goals.

~ Brent Reitze, Applicant for Director of Publication, United States Transhumanist Party, April 2, 2019


As mentioned in some recent articles, we are increasing our efforts to reward our loyal and invaluable monthly patrons that support us as Lifespan Heroes. We previously mentioned a brand-new, exclusive webinar series for Lifespan Heroes, and we want to take this opportunity to also announce another brand-new initiative that will commence in April.

Introducing the Longevity Book Club for Lifespan Heroes

As special thanks to our Lifespan Hero patrons, we are pleased to announce the launch of our new Longevity Book Club, where you can join other longevity enthusiasts in reading the most interesting works that relate to our mission of ending age-related diseases. You will also get the opportunity to listen to discussion panels and take part in Q&A sessions that are focused on books that touch on these important scientific, philosophical, moral and futuristic longevity topics. This is the ideal place to meet like-minded longevity enthusiasts who are working on building their knowledge on longevity and all of the implications that come with ending age-related diseases.

Our first book circle will be reading Homo Deus: A Brief History of Tomorrow by Yuval Noah Harari, a New York Times best-selling author.

Here is a brief synopsis of the book:

Yuval Noah Harari, author of the critically-acclaimed New York Times bestseller and international phenomenon Sapiens, returns with an equally original, compelling, and provocative book, turning his focus toward humanity’s future, and our quest to upgrade humans into gods.

Over the past century, humankind has managed to do the impossible and rein in famine, plague, and war. This may seem hard to accept, but, as Harari explains in his trademark style—thorough, yet riveting—famine, plague and war have been transformed from incomprehensible and uncontrollable forces of nature into manageable challenges. For the first time ever, more people die from eating too much than from eating too little; more people die from old age than from infectious diseases; and more people commit suicide than are killed by soldiers, terrorists and criminals put together. The average American is a thousand times more likely to die from binging at McDonalds than from being blown up by Al Qaeda.

What then will replace famine, plague, and war at the top of the human agenda? As the self-made gods of planet earth, what destinies will we set ourselves, and which quests will we undertake? Homo Deus explores the projects, dreams and nightmares that will shape the twenty-first century—from overcoming death to creating artificial life. It asks the fundamental questions: Where do we go from here? And how will we protect this fragile world from our own destructive powers? This is the next stage of evolution. This is Homo Deus.

With the same insight and clarity that made Sapiens an international hit and a New York Times bestseller, Harari maps out our future.

We feel this is a good book to get started with, as it’s written in a user-friendly style that can appeal to a broad audience and touches on many topics that are directly or indirectly related to our mission of ending age-related disease. As we progress as a group, we will shift into different categories, including philosophy, genetics, biochemistry, ethics, and many more topics that are of interest to our mission and book club members.

As a Hero, you will have the opportunity to join us for the first of many book discussions and have the opportunity to learn about the fascinating knowledge that these authors have to share with us as well as the deconstructed meanings behind the books as seen by our book club members. We’ll email the connection instructions to our Heroes soon, so please check your inbox for our announcement.

Calling all the Heroes

This year, our plan is to reach out to an even wider audience and engage with them about the need to end age-related diseases. We aim to hire another team member so that we can cover more news stories, buy new equipment, produce more films with popular Youtube channels, launch a two-day conference in NYC, and do more online shows, including this new webinar series.

However, to do this, we need your help.

We are very grateful for the support of our monthly patrons, the Lifespan Heroes, and we are asking you to consider joining them today in order to help us achieve our ambitious goals for 2019.

By becoming a Lifespan Hero, you become a monthly patron and can change or halt your contributions at any time. In return for your support, you get access to the Heroes’ private Discord channel, enjoy discounts on our event tickets, get early access to conference videos and live access to webinars, and receive regular reports on our progress and future plans.

Please consider becoming a Lifespan Hero today. We look forward to seeing you at the MitoSENS webinar and our Longevity Book Club meetings.

3 Reasons Why “Ending Suffering” Should Be the #1 Transhumanist Priority – Article by Hank Pellissier

3 Reasons Why “Ending Suffering” Should Be the #1 Transhumanist Priority – Article by Hank Pellissier

Hank Pellissier


Editor’s Note: The U.S. Transhumanist Party / Transhuman Party features this proposal by our member Hank Pellissier for a new website called Paradise2040, which will focus on the abolition of involuntary suffering and incremental ways of getting there within the next 21 years. This is an endeavor supported by Article IV of the Transhumanist Bill of Rights, Version 3.0. It is also a current within transhumanist thinking that, as Mr. Pellissier points out, could bring additional support to the movement. Different transhumanists will have different views as to what the most important aims of transhumanism should be. As an organization that embraces pluralism and diversity of thought, the U.S. Transhumanist Party / Transhuman Party would encourage any of our members who agree with the direction Mr. Pellissier proposes to collaborate with him on the creation of the Paradise2040 website.

~ Gennady Stolyarov II, Chairman, United States Transhumanist Party / Transhuman Party, March 25, 2019


A survey I conducted in 2010 of 818 transhumanists identified “brain enhancement” as the #1 priority, with “maximizing” health and life extension as #2 and #3.  The top three “values” of the U.S. Transhumanist Party (the Core Ideals) are #1) Life Extension, #2) “a cultural, societal, and political atmosphere informed and animated by reason, science, and secular values”, and #3) “to reduce and eliminate existential risks.”

I believe all these ambitions are important, but over-rated and mis-placed. My opinion, after ten years as a transhumanist, is this: the #1 goal of H+ should be the Abolition of Suffering. My view is advocated by multiple transhumanists, notably David Pearce, but… we’re in the minority.

Here’s three reasons why Abolition of Suffering deserves top consideration:

#1: Eternal Pain = Torture. It is shallow-thinking to not recognize super-longevity in a state of pain as undesirable; in fact, it is masochistic/sadistic. Ask yourself this: would you rather live 60 years in a state of bliss, joy, love, ecstasy, or at least moderate happiness, than exist for 120 years in pain, fear, anguish, despair, and horror? Quality of life is far more important than quantity, IMO.

I have three friends who suffer from depression. When I talk about “ending death”, they sigh forlornly and admit that they are “ready to die”, “sick to death of themselves”, and “have been punished by life long enough.” These people don’t want or need additional decades of misery, they need “happy days” as soon as possible. Hundreds of millions of humans live with chronic physical, mental, and emotional pain, and even the rest of us would appreciate higher doses of joy.

#2: Marketing “Ending Pain” sells better than “Ending Death.” When I tell acquaintances I’m a transhumanist and our #1 goal is elimination of death, they usually roll their eyes and dismiss me as a death-phobic weirdo. Sure, we can castigate these critics with the “Deathist” slur, but it is a superior strategy, I believe, to find common ground. Informing folks that the primary ambition of transhumanists is to elevate human happiness advertises us as charity-givers of cheerfulness, humanitarians of happiness, altruists of euphoria. Instead of billing ourselves as Slayers of the horrible Grim Reaper, we can offer ecstasy, contentment, increased friendship networks, psychedelic discoveries, purpose in life, etc. Recruitment will skyrocket!

#3: “Abolition of Suffering” is more Inclusive. Teenagers usually aren’t nervous about death, but they’re anxious about depression, body shame, bullying, and disempowerment, and don’t like their elders groaning and moaning in anguish. Religionists believe death opens a gate to heaven, but they experience the same pain from auto accidents, arthritis, and Alzheimer’s as atheists do, and they’re on board with extinguishing this.

My activist plan to end suffering is to launch a website called Paradise2040 – to promote cessation of suffering in the next 21 years.  The website will be ‘practical’ but fun and imaginative; it will list dozens of pains from hangnails to herpes to homelessness with links to research-supported cures and potential futurist remedies.

If anyone wants to help – contact hankpellissier@yahoo.com.

 

 

 

Enlightenment Transhumanist Association Registered in Nigeria – Press Release by Leo Igwe

Enlightenment Transhumanist Association Registered in Nigeria – Press Release by Leo Igwe

Leo Igwe


A transhumanist organization, Enlightenment Transhumanist Forum of Nigeria (ETFN) also known as H+ Nigeria, has been licensed to operate in the country. Nigeria’s Corporate Affairs Commission, the agency that is in charge of registering societies issued the license on August 7, 2018. H+ Nigeria was registered after it fulfilled all the conditions required for operation as a legal entity in the country. The objectives of the organization include the promotion of transhumanist thought and culture. The forum plans to create awareness of the radical changes and feasibility of redesigning the human condition which humanity stands to undergo through science and technology in the future.

The organization will also encourage the growth of technological culture in a broad range of emerging, sophisticated technologies. In addition, it will promote ethical principles and methods of adopting new and emerging technologies in Nigeria beyond.

Furthermore, the ETFN will advocate the moral right for those who so wish to use technology to extend their mental and physical capacities and to improve their control over their own lives. Also, it will encourage systematic research and create a forum where people can rationally debate what needs to be done and advocate for a social order where responsible decisions on transhumanist principles can be implemented. It is most exciting that such a platform for furthering the ideals of transhumanism, and other futurist philosophies, has been incorporated in Nigeria.

Benefit for U.S. Transhumanist Party Members: Discounts Offered for Treatments from AmpliCell Medical

Benefit for U.S. Transhumanist Party Members: Discounts Offered for Treatments from AmpliCell Medical

AmpliCell Medical


The U.S. Transhumanist Party is pleased to announce that any member who joins us for free via our online application form will also be eligible to receive discounts on procedures from AmpliCell Medical, one of our Allied Organizations, located in the Los Angeles area and specializing in regenerative medicine and stem-cell therapies.

Members who join will receive a confirmation e-mail, which will be sufficient to provide to AmpliCell Medical at the time of a consultation. 

• 40% Discount off of Stem-Cell Treatments: The standard cost is $8,900 for the first treatment and $4,500 for follow-up treatments (if needed). The therapy is investigational and done as part of a clinical trial according to Institutional Review Board (IRB) approved protocols. With the 40% discount, the first treatment would cost $5,340, and a follow-up treatment would cost $2,700.

• 10% Discount off of Bio-Identical Hormone Replacement – First Consultation: The standard cost is $495 for the first consultation. With the 10% discount, that cost would be reduced to $445.50.

Of course, the U.S. Transhumanist Party is not itself a medical organization and does not provide medical advice. Each reader should take account of his or her own individual circumstances, health, medical history, skills, and knowledge when evaluating which courses of action to pursue, and also consult a medical professional with regard to decisions that may have a major impact on health. However, for those individuals whom stem-cell therapies could help, membership in the U.S. Transhumanist Party now offers the opportunity to achieve significant cost reductions in particular treatments.


Description from AmpliCell Medical. Learn more at http://amplicellmedical.com/:

The Fountain of Youth is no longer a myth. It is found within you, in the form of your very own stem cells. Stem cells are our bodies’ own, built-in healing cells, which naturally reside within certain tissues of the body. They start out in a dormant state and are “switched on” by the chemical signals produced by damaged tissues, acting to repair and regenerate damaged cells. Stem cells derived from your own tissues may well be the next major advance in medicine.

While early stem-cell research has been associated with the controversial use of embryonic stem cells, at AmpliCell Medical we use adult mesenchymal cells extracted directly from your own fat. We use a sterile closed surgical system to process 50 cc of fat from a mini-liposuction procedure in order to isolate and implant your own source of regenerative cells on the same day. “Closed surgical system” means that it never comes in contact with the outside world and is kept in a completely sterile environment. The regenerative cells are found in the SVF (stromal vascular fraction) that contains autologous mesenchymal stem cells, macrophage cells, endothelial cells, immune regulatory cells, red blood cells, and important growth factors that promote stem-cell activity. Our technology allows us to isolate high numbers of viable cells.

At AmpliCell Medical we are committed to helping people with wide variety of degenerative and inflammatory conditions. We offer a state-of-the-art minimally invasive procedure that utilizes autologous adipose (fat) derived stem cells.

Diseases and conditions currently being studied:

  • Orthopedics: Neck Arthritis, Back Arthritis, Knee Arthritis, Hip Arthritis, Elbow and Hand Arthritis, Shoulder Arthritis
  • Neurology: Lyme Disease, Peripheral Neuropathy, Multiple Sclerosis, Parkinson’s Disease, Strokes, ALS Amyotrophic Lateral Sclerosis, Muscular Dystrophy
  • Cardiac/Pulmonary: COPD, Post-MI Myocardial Infarction, Congestive Heart Failure and Cardiomyopathy, Chronic Lung Diseases, Asthma
  • Urological and Digestive: Interstitial Cystitis, Peyronies Disease, Erectile Dysfunction, Male Incontinence, Crohn’s Disease
  • Cosmetic Applications: Hair Loss, Skin Health
  • Others: Wellness and Anti-Aging, Hormone Balance, Sport Injuries

THE STUDIED BENEFIT OF STEM-CELL THERAPY

  • Regenerate cells, tissues and organs
  • Repair and reconstruction of joints and strengthening
  • Increase flexibility of joints and articular disc
  • Optimize the immune system
  • Alleviation of menopausal symptoms
  • Improve hormone secretion
  • Increase alertness and mental awareness
  • Refine skin for a healthy glow
  • Improve skin texture, elasticity and thickness
  • Improve sleep pattern
  • Improve blood circulation
  • Enhance stamina and energy
  • Renew sexual abilities and performance
  • Accelerate thinking ability; improve memory

How are stem cells deployed?

There are varying methods for deployment of stem cells based on the condition being treated. The stem cells can be injected directly into joints or even organs as needed, intravenously into the veins, or even into spinal fluid. All redeployment methods are minimally invasive and can be done in outpatient procedures. Since we are using a patient’s own cells, there is no risk of rejection or allergenic reactions that are common in many other procedures.

Will my treatment work, and how long will it take?

Adult stem-cell treatments are currently considered experimental and are not completely understood, how well a patient responds to our treatments will be different in each case and depends greatly on the disease or condition and how severe the case may be. There are regulations by the FDA which will not allow AmpliCell Medical to make any direct claims about the curing or treating any diseases specifically, but, if you want to consult about the procedure, we can lay out expectations based on research data and actual cases prior to treatment.

Stem cells are part of your body’s natural healing process and can take time for effects to take place; however, some conditions can see immediate results.

Who is eligible as a candidate for treatment?

Only specific medical conditions and problems are being treated by AmpliCell Medical at this time. Patients who want to have the treatment done must be medically stable and may be not be able to participate due to the nature and severity of their condition. Any patients that have uncontrolled cancers or active infections are not able to undergo the SVF (Stromal Vascular Fraction) procedure and must have their conditions treated before undergoing the procedure. Another consideration is that patients with bleeding disorders or taking blood-thinner medication must be evaluated before having treatment. When a patient is selected for the procedure, they must keep in mind that they are taking part in patient-sponsored research, and there are no other incentives other than possible results of the treatment.

Read more at AmpliCell Medical’s FAQ here

The Longevity Film Competition – Announcement by SENS Research Foundation, The Healthy Life Extension Society, and International Longevity Alliance

The Longevity Film Competition – Announcement by SENS Research Foundation, The Healthy Life Extension Society, and International Longevity Alliance

SENS Research Foundation
The Healthy Life Extension Society 
International Longevity Alliance


Editor’s Note: The U.S. Transhumanist Party encourages its members to participate in the Longevity Film Competition, whose official website can be found here. The more original attempts exist to convey to the general public the feasibility and desirability of indefinite life extension, and to dispel common misconceptions about it, the sooner we will have the critical mass of public support needed to bring about this most vital goal. 

~ Gennady Stolyarov II, Chairman, United States Transhumanist Party, July 15, 2018


Contest Introduction: 

We are living in very interesting times, times of constant change. The scientific community is telling us that soon we could enjoy much healthier and longer lives thanks to technological advancements happening at an accelerated rate. The future can be bright and healthy, and we want more people to know about this amazing prospect and want them to get involved in this important mission – the mission of healthy longevity.

However, describing something potentially beautiful is not always easy. We think you can help by making a (very) short movie conveying that a longer and healthier life thanks to sustainable medical interventions, will be a very positive thing for citizens and society alike.

Help us spread the word in the right way, help us make sure people understand this is about health and that for the first time in history the possibility of tackling aging is not science fiction, but science fact.

Join us in this crusade by entering our competition presented by the SENS Research Foundation, The Healthy Life Extension Society and the International Longevity Alliance and not only potentially help saving lots of lives, but also win the first prize of $10,000!

We look forward to your ideas on how to better communicate this important message to the world.

– The Longevity Film Competition team

Contest Guidelines: 

Even though putting aging under medical control is probably desirable to most humans, this concept is not always clear to everybody.

One of our goals is to use this competition as a vehicle to clarify and demystify some of the misconceptions we hear very often.

You can choose just one or all of them and explain them in any way you choose, using your own language and ideas.

Misconception #1

“Aging and disease are two separate things.”

CLARIFICATION:

— Aging causes disease, and they should be treated as one. —

As we age, we lose our health. We cannot age and become elderly without eventually getting ill as a result of it. If we live long enough, we will all get sick of one or several of the diseases of aging and eventually succumb to them. When we talk about eliminating aging, we talk about putting this process under medical control so that we don’t have to get sick as we age.

Misconception #2

“If I live to a 150, I will be living for a long time in an old, sick body.”

CLARIFICATION:

— If these new therapies help us live to a 150, it will only be because they will keep us strong and healthy. —

When we talk about extending our lifespan, we are talking about extending our health. The extension of our life will not happen unless we fix the health problems that come with aging. Once we do this, more longevity will happen as a “side benefit” of being healthier. As we said before, we get sick with aging, and that’s why most of humans die of old age.

So, if we will still be alive at 150, this will mean we will have a better control of the aging process through medical interventions – hence we should not be living in an old sick body.

Misconception #3

“Aging is natural, and we shouldn’t tamper with the natural.”

CLARIFICATION:

— Combating aging is a great challenge for Humanity, and we have a long history of getting great benefit from tampering with many natural things. —

It is proven that there are endless ‘unnatural’ things created by humans of enormous value and positive outcomes, and we can imagine only a minuscule number of people who would choose to live without them — especially when it has to do with suffering, disease and death.

A few examples of unnatural things we use all the time without questioning much are: pacemakers, antibiotics (to kill natural bacteria), painkillers, cochlear implants, dialysis, plastic surgery, airplanes (it is not natural for us to fly), hair coloring, prosthetic limbs, contact lenses, birth-control methods, and the list goes on forever.

On the other hand, here are some natural things that are definitely bad for us: earthquakes, hurricanes, mudslides, tornadoes, infectious microorganisms, poisonous plants, predators, venomous creatures, fire, gravity (when we fall), tsunamis, radiation, meteor impacts, etc.

It is time to reason and understand that “natural” doesn’t necessarily mean “good”.

Misconception #4

“These therapies will only be for the rich.”

CLARIFICATION:

— Healthy longevity therapies are being developed for everybody to access. —

Rejuvenation therapies could be as little reserved for rich people as mobile phones, cars, electricity, or vaccination may have been in the beginning. Like for most technological progress, the research may be complicated and expensive, but once the technology becomes available, it will become available for everybody. One good example is that the first Human Genome took $2.7 billion dollars and almost 15 years to complete. In 2001 the price of sequencing a genome was 100 Million dollars; today is under 1000 dollars, and it will keep going down without a doubt. Humanity has never stopped advancing just because it was harder and less cost-effective in the beginning; if we had thought like that, we would probably not have most of the technology that is available for everybody today. That’s one more reason why it’s so important not to delay the development of these cures.

Official Rules

  1. Concept of film: The submitted piece should show that medical progress for a healthier and longer life is generally a good thing for citizens and society alike. You will achieve this by using the list of common misconceptions provided in the Guidelines section above. You must choose at least one and may also choose all of them.
  2. Length: The length of the film should be a minimum of 1 minute and a maximum of 20 minutes.
  3. Visual art style: All kinds of visuals are allowed:
    Films, computer animations, whiteboard drawings, live action, infographics, stop and motion, cartoons, typography, screencast, etc.
  4. Genre: All genres are allowed. Science, fiction or science-fiction, a story, sad or funny, a docufiction, a documentary, etc.
  5. Copyright: All material used in the video should be original, or you should own the copyright for it. You may not use copyrighted material for which you don’t have the rights. If you fail to follow this rule, your film will be automatically disqualified.
  6. Submission: The submission deadline is 23:59 GMT September 15, 2018. The final work should be uploaded to the Internet, and a link to watch it should be provided to us via email at contact@longevityfilmcompetition.com, together with your last name, first name, and the proposed title of the work. The winners will be announced October 1st (International Longevity Day).
  7. Language: The official language is English. Videos can also be submitted in French, Spanish, Italian, German, Russian and Dutch but would need to have English subtitles.
  8. Work Originality and Permissions: a) Films must be the original work of the applicants, and they must be unpublished before July 1st, 2018. b) If a film is based upon another person’s life or upon a book or other underlying work, applicant(s) must secure any necessary rights to make such adaptations. c) By entering the competition, you represent that you have secured all necessary rights. d) Applicants are solely responsible for obtaining all necessary rights and permissions for third-party materials included in their films, including but not limited to music, trademarks, logos, copyrights, and other intellectual property rights. e) Longevity Film Competition (LFC) expressly disclaims all liability or responsibility for any violations of the foregoing. f) If your submission is selected for a prize, you agree that SENS Research Foundation (SRF), The Healthy Life Extension Society (Heales), and the International Longevity Alliance (ILA) use your movie without restriction to promote the mission of curing the diseases of aging. SRF, Heales and the ILA can show your work on the internet or by all other means. g) SRF, Heales and the ILA are non-profit organizations and may use the films to drive donations from the public, which will be used to advance the mission of healthy longevity. Any funds raised though the films will support scientific research, outreach, and/or education programs.
  9. Selected Films and Winners: a) LFC has no obligation (other than as stated in these rules or on our website) to disclose any of the following information: i) identities of screeners or judges; ii) notes, feedback, or information relating to the submitted project; and/or iii) details regarding the submission review or selection process. b) LFC explicitly disclaims any liability or responsibility for any comments, notes, or opinions expressed about a submission, whether by LFC or by its volunteers.  c) Winners will be announced on October 1st, 2018. The judges’ decision is final. Winners receiving cash prizes are solely responsible for payment of all applicable local, state, and federal taxes.
  10. Legal action: In the event of litigation the competent courts will be those of the Brussels jurisdiction in Belgium.
  11. Additional information: For all issues not mentioned above, the members of the jury will decide. They must decide in equity and with the same rules for all competitors.

COMPETITION LEGAL TERMS

BY SUBMITTING THE MATERIAL PARTICIPANTS  AGREE:

To having read all of the rules, understood, and have complied with these rules.

To warrant that their work is original and that there are no disputes regarding the ownership of their submission.

To warrant that the submitted material does not defame or invade the rights of any person living or dead.

That failure to adhere to the competition rules and regulations will result in disqualification.

That no revisions of materials will be accepted once entry has been submitted.

That to the best of their knowledge, all the statements herein are true and correct.

TO INDEMNIFY, HOLD HARMLESS, AND DEFEND THE COMPETITION, ITS EMPLOYEES, VOLUNTEERS, DIRECTORS, JURORS, REPRESENTATIVES, AND AFFILIATES FROM ALL LIABILITY, CLAIMS, AND DAMAGES IN CONNECTION WITH THE SUBMISSION AND FROM ANY FEES AND EXPENSES, INCLUDING BUT NOT LIMITED TO REASONABLE ATTORNEYS’ FEES, THAT ANY OF THEM MAY INCUR IN CONNECTION THEREWITH.
“I Am Transhuman” T-Shirt by Duarte Baltazar

“I Am Transhuman” T-Shirt by Duarte Baltazar

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Duarte Baltazar


Filmmaker Duarte Baltazar of Utopian Focus has made available the “I Am Transhuman” T-Shirt for sale on Amazon.com, in an effort to fund the creation of further documentary films about the transhumanist movement. (See an example of a short film by Mr. Baltazar, “The Hedonistic Imperative“.) The U.S. Transhumanist Party offers this announcement to its members as another possibility for raising public awareness of transhumanism as well as spreading the expression and hashtag #IAmTranshuman, part of the Transhuman Present project.

Order the “I Am Transhuman” T-Shirt on Amazon here for the price of $19.99.

Color Options: Black, Asphalt, Royal Blue, Cranberry, and Purple

Various male, female, and child sizes are available.

Product Description

  • Solid colors: 100% Cotton; Heather Grey: 90% Cotton, 10% Polyester; All Other Heathers: 50% Cotton, 50% Polyester
  • Imported
  • Machine-wash cold with like colors, dry low heat
  • I Am Transhuman – Transhumanist Movement
  • Art, Ethics, Philosophy, Design T-Shirt
  • Lightweight, Classic fit, Double-needle sleeve and bottom hem