Tag: Sierra Sciences

Dr. Bill Andrews and U.S. Transhumanist Party Chairman Gennady Stolyarov II Discuss Transhumanism and RAADfest at Sierra Sciences

Dr. Bill Andrews and U.S. Transhumanist Party Chairman Gennady Stolyarov II Discuss Transhumanism and RAADfest at Sierra Sciences

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Gennady Stolyarov II
Bill Andrews

On October 12, 2019, Brent Nally recorded this discussion between Dr. Bill Andrews – the Biotechnology Advisor of the U.S. Transhumanist Party / Transhuman Party – and U.S. Transhumanist Party / Transhuman Party Chairman Gennady Stolyarov II regarding recent news in the field of longevity (including pet longevity), techniques to slow down the rate of telomere shortening, changes to public perceptions of aging and longevity, transhumanism and technologies of life enhancement, and how to be rigorous and appropriately skeptical when evaluating various ideas and hypotheses in medicine.

Watch this discussion here and be on the lookout for a special visitor from a different species!

Become a member of the U.S. Transhumanist Party / Transhuman Party here for free, no matter where you reside.

Show Notes by Brent Nally

0:35 Dr. Andrews links:

Facebook: https://facebook.com/telomere.bill.andrews;

Linkedin: https://linkedin.com/in/william-h-andrews-5455b45/;

Wikipedia: https://en.wikipedia.org/wiki/William_H._Andrews_(biologist);

Sierra Sciences Website: https://sierrasci.com/;

Sierra Sciences YouTube Channel: https://www.youtube.com/channel/UCB9UFIxyD9VUHjuNQzpLzeA

1:08 Brent’s RAADfest 2019 YouTube playlist. Go to RAADfest primarily to network https://www.raadfest.com/

2:35 USTP concluded its presidential primary elections: watch Gennady Stolyarov II & Johannon Ben Zion at RAADfest 2019; watch Brent interview Mr. Ben Zion at RAADfest 2019; watch Brent interview Mr. Ben Zion and his VP running mate Charlie Kam at RAADfest 2019.

3:10 Bill’s dog Dash makes his cameo appearance.

4:35 Long-distance running and recovery.

7:20 Bill hosted a pet-longevity panel at RAADfest 2019.

12:15 Quacks and charlatans have discredited human longevity for centuries.

13:26 How has the public’s perception of human aging changed in the last decade?

15:10 Buy Bill’s 2 books: Curing Aging and Telomere Lengthening. See Brent’s book review of Telomere Lengthening: Curing all diseases including cancer & aging by Dr. Bill Andrews

15:25 Inflammation is the number one cause of human aging.

16:47 Do fun activities, meditate, practice yoga, eat a healthy diet, reduce stress to decrease the rate of telomere shortening.

18:48 Caldwell Esselstyn – Wikipedia

19:10 Watch Brent’s interview with Dr. Sandy Kaufmann.

21:33 Funding is needed to cure human aging and all chronic diseases.

24:03 Bill is hoping the telomerase gene therapy clinical study by Libella Gene Therapeutics (which is scheduled to start in November 2019) will show age reversal in the human Alzheimer’s patient in every measurable way.

24:18 Mice telomerase gene therapy study by Dr. by Ron DePinho

26:13 Animals age in different ways.

30:35 Life enhancement should be our focus.

33:08 Most humans living in the 1st world have been transhumanists for quite some time.

35:38 Nanobots

38:02 Get involved in the longevity movement in any way you can – follow thought leaders; donate.

39:40 Dr. Jason Williams

40:30 A race to cure human aging is a great idea to educate people.

43:26 Watch Brent’s interview with USTP Presidential candidate Johannon Ben Zion.

45:15 Spinal-cord repair, prosthetics, stem cells, etc.

51:01 Bill is impressed by stem-cell therapies but warns of charlatans. Watch Brent’s playlist on stem cells.

52:38 Use PubMed to do a meta-analysis of scientific peer-reviewed studies.

Brent Nally Interviews U.S. Transhumanist Party Chairman Gennady Stolyarov II at Sierra Sciences

Brent Nally Interviews U.S. Transhumanist Party Chairman Gennady Stolyarov II at Sierra Sciences

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Gennady Stolyarov II
Brent Nally

On October 12, 2019, U.S. Transhumanist Party Chairman Gennady Stolyarov II spoke with Brent Nally at the venerable Sierra Sciences headquarters in Reno, Nevada. They discussed developments in the U.S. Transhumanist Party, fitness, health, and longevity – among other subjects.

Watch the interview here.

Become a member of the U.S. Transhumanist Party / Transhuman Party here for free, no matter where you reside.

Show Notes by Brent Nally

3:15 Brent Nally’s RAADfest 2019 YouTube playlist: https://www.youtube.com/playlist?list=PLGjySL94COVSO3hcnpZq-jCcgnUQIaALQ

4:24 Go to RAADfest primarily to network: https://www.raadfest.com/

6:28 People Unlimited website: https://peopleunlimitedinc.com/

6:30 The Coalition for Radical Life Extension website: https://www.rlecoalition.com/

7:20 We need to increase your healthspan to increase your lifespan.

9:01 Watch Bill Andrews and Gennady discussing transhumanism and radical life extension: https://www.youtube.com/watch?v=U7GJrVBp8FQ

13:35 Gennady just ran the Lakeside Marathon at Lake Tahoe the day before, October 11, 2019.

19:30 Do whatever type of exercise that you enjoy. Don’t push yourself to the point of exhaustion where you’re throwing up or getting injured or not having fun because that’s bad for your telomeres.

24:10 Audit your own thoughts daily as a meditation to recognize your limiting beliefs.

26:15 How Gennady became Chairman of the U.S. Transhumanist Party

29:35 How the 9 USTP presidential candidates competed using a “ranked preference” approach

32:07 43 articles are currently in the 3rd version of the Transhumanist Bill of Rights: https://transhumanist-party.org/tbr-3/

34:27 https://transhumanist-party.org/

35:40 We should be more concerned with ideas rather than people. We’re in an “ideas” economy.

36:28 Politicians are more followers than leaders.

40:27 3 core ideals of USTP: https://transhumanist-party.org/values/

41:40 Gennady shares more details about how his role as chairman may evolve.

44:28 Positives and negatives of centralization and decentralization

49:15 Sophia the AI robot: https://www.hansonrobotics.com/sophia/

51:30 Truth is sometimes stranger than fiction. Try to educate others about transhumanism.

55:30 Ray Kurzweil points out that technology growth and stock market growth are separate. Here’s Brent talking to Ray in February 2011: https://www.youtube.com/watch?v=3TuVn…

57:37 Join the USTP: https://transhumanist-party.org/membership/

58:40 USTP Twitter: https://twitter.com/USTranshumanist; USTP LinkedIn: https://www.linkedin.com/company/19118856/; Gennady’s online magazine – The Rational Argumentator: http://www.rationalargumentator.com/index/

1:01:14 Gennady, Bill Andrews, and Brent ran about 8.4 miles the next morning above Carson City, NV on the Upper Clear Creek Trail.

1:02:15 Don’t forget to subscribe, like, comment on this video, and share on your social media accounts!

Dr. Bill Andrews Interviewed by John Murrieta of the Science-Based Species Channel

Dr. Bill Andrews Interviewed by John Murrieta of the Science-Based Species Channel

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Bill Andrews
John Murrieta

John Murrieta of the channel Science-Based Species interviewed Dr. Bill Andrews, the U.S. Transhumanist Party’s Biotechnology Advisor, in October 2018. Watch this interview on YouTube here.

In this video, Dr. Andrews discusses the research he does at Sierra Sciences with the aim to reverse aging and extend lifespans by extending telomeres, as well as the forthcoming gene-therapy clinical trial by Libella Gene Therapeutics.

This interview with recorded by U.S. Transhumanist Party Secretary Bobby Ridge at the Fifth Enlightenment Salon, hosted by U.S. Transhumanist Party Chairman Gennady Stolyarov II.

Fourth Enlightenment Salon – Health Segment: Discussions on GMOs, Calorie Restriction, Genetics, Artificial Sweeteners, CBD

Fourth Enlightenment Salon – Health Segment: Discussions on GMOs, Calorie Restriction, Genetics, Artificial Sweeteners, CBD

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Gennady Stolyarov II
Bill Andrews
Bobby Ridge
John Murrieta

This is the second video segment from Mr. Stolyarov’s Fourth Enlightenment Salon. Watch the first segment here.

On July 8, 2018, during his Fourth Enlightenment Salon, Gennady Stolyarov II, Chairman of the U.S. Transhumanist Party, invited John Murrieta, Bobby Ridge, and Dr. Bill Andrews for an extensive discussion about transhumanist advocacy, science, health, politics, and related subjects.

Topics discussed during this installment include the following:

• Why genetically modified organisms (GMOs) are mostly good for you, and most negative perceptions of GMOs should really just be directed at the corporate practices of one company but not genetic modification as a whole.

• What technologies are already aiding the disabled and dramatically extending their capabilities in daily life.

• The role of genetics in longevity and the future of somatic genome editing.

• What the scientific evidence suggests regarding the impact of caloric restriction in humans and other primates.

• CBD and cannabinoids: separating the evidence from the marketing.

• Sierra Sciences’ history of testing over a million compounds for effects on telomerase induction.

• Why artificial sweeteners also should not be maligned, and there is no scientific evidence of their harms.

Join the U.S. Transhumanist Party for free, no matter where you reside by filling out an application form that takes less than a minute. Members will also receive a link to a free compilation of Tips for Advancing a Brighter Future, providing insights from the U.S. Transhumanist Party’s Advisors and Officers on some of what you can do as an individual do to improve the world and bring it closer to the kind of future we wish to see.

New Clinical Study May Be the World’s First Cure for Alzheimer’s Disease – Press Release from Libella Gene Therapeutics

New Clinical Study May Be the World’s First Cure for Alzheimer’s Disease – Press Release from Libella Gene Therapeutics

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Libella Gene Therapeutics

ORLANDO, Fla., Jan. 10, 2018 /PRNewswire/ — Libella Gene Therapeutics LLC will conduct an OUS (outside the United States) clinical trial in Cartagena, Colombia, using gene therapy to reverse age-related diseases, starting with Alzheimer’s. Unlike traditional drugs, which tend to be taken for months or years at a time, gene therapy interventions are intended to be one-off treatments that tackle a disease at its source, repairing faulty DNA and allowing the body to fix itself.

Every day 228 Americans die from Alzheimer’s disease, and there is currently no known treatment or cure. Gene therapy offers the ability to permanently correct a disease at its most basic level, the genome, and could offer cures for many conditions that are currently considered incurable. According to Dr. Bill Andrews, the scientist leading the study, “Human telomerase reverse transcriptase (hTERT) is an enzyme whose expression plays a role in cellular aging and is normally repressed in cells, resulting in progressive shortening of telomeres. Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer.”

By inducing telomerase, Dr. Andrews and Libella Gene Therapeutics hope to lengthen telomeres in the body’s cells. The clinical trial will treat a limited number of patients using the gene therapy treatment, which has been demonstrated as safe, with minimal adverse reactions in over 186 clinical trials.

Dr. Andrews has been featured in Popular Science, on the “Today” show and in numerous documentaries on the topic of life extension. As one of the principal discoverers of both the RNA and protein components of human telomerase, Dr. Andrews was awarded second place as “National Inventor of the Year” in 1997. He earned a Ph.D. in molecular and population genetics at the University of Georgia in 1981. He has served in multiple senior science and technology roles at leading bioscience corporations. Dr. Andrews is a named inventor on over 50 U.S.-issued patents on telomerase and is the author of numerous scientific research studies published in peer-reviewed scientific journals.

On why the company decided to conduct its clinical research project outside the United States, Libella Gene Therapeutics president Dr. Jeff Mathis said, “Traditional clinical trials in the U.S. can take years and millions — or even billions — of dollars. The research and techniques that have been proven to work are ready now. We believe we have the scientist, the technology, the physicians, and the lab partners that are necessary to get this trial done faster in Colombia.”

The clinical trial is prepping to begin in the first quarter of 2018 and will be conducted at MediHelp Services Clinic in beautiful and tourist-friendly Cartagena, Colombia. The state-of-the-art facility has hosted international public figures including athletes, celebrities and politicians. Dr. Javier Hernandez, MediHelp’s medical director, will oversee the trial.

Colombia’s clinical research regulation is friendly to gene therapy trials, with one of the fastest approval times in Latin America for this kind of research. The trial’s clinical study design; regulatory, operation and logistical support; project management; statistical analysis; and study monitoring services will be provided by LATAM Market Access Inc., a Florida-based clinical research company.

About Libella Gene Therapeutics LLC 
With a mission to reverse aging and cure all age-related diseases, starting with Alzheimer’s, Libella Gene Therapeutics has exclusively licensed the AAV Reverse (hTERT) transcriptase enzyme technology from Sierra Sciences and Dr. Bill Andrews. More information at www.libellagenetherapeutics.com.

About LATAM Market Access Inc.
Dedicated to helping innovative life science companies gather cost-effective clinical data at leading research institutions, the company provides clinical study design; regulatory, operational and logistics support; project management; statistical analysis; and study monitoring services. More information at www.latammarketaccess.com.