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The Best of the SENS AMA – Article by Steve Hill and Aubrey de Grey

The Best of the SENS AMA – Article by Steve Hill and Aubrey de Grey

Steve Hill

Dr. Aubrey de Grey


Editor’s Note: In this article, Steve Hill highlights the Ask Me Anything on Reddit held on December 7th by Dr. Aubrey de Grey.  This article was originally published by the Life Extension Advocacy Foundation (LEAF).

                   ~ Kenneth Alum, Director of  Publication, U.S. Transhumanist Party, December 13, 2017

 

Dr. Aubrey de Grey from the SENS Research Foundation (SRF) did an Ask Me Anything on Reddit on December 7th, and there were many great questions and answers; we thought it would be a great time to summarize some of the best ones and offer a little commentary.

What do you think were the biggest wins of the last couple of years in SENS-relevant advocacy, research, and development? What has moved the needle?

There have been lots. On the research, I would highlight our paper in Science two years ago, which shows how to synthesize glucosepane, and our paper in Nucleic Acids Research one year ago, which shows simultaneous allotopic expression of two of the 13 mitochondrial genes. Both of those projects have been greatly accelerated in the meantime as a result of those key enabling breakthroughs; watch this space.

On advocacy, I think the main win has been the arrival of private capital; I would especially highlight Jim Mellon and his Juvenescence initiative because he is not only a successful, energetic and visionary investor, he is also a highly vocal giver of investment advice.

We are pleased to have been involved with the second project mentioned here, as we hosted the MitoSENS project at Lifespan.io, where it raised 153% of its initial fundraising goal. Less than a year later, after raising this money, it went on to publish the groundbreaking study showing that backup copies of mitochondrial genes could indeed be created in the nucleus. Dr. de Grey originally proposed the idea over a decade ago amid much scepticism; it is really good to see that years later he has been vindicated. This is the power of crowdfunding and how we as a community can make big changes in science by working together.

How do you feel about the impact of groups like LEAF advocating and reporting on rejuvenation biotech? Has the advocacy and reporting of these groups made your life any easier?

Massively! A huge thing that I say all the time is that advocacy absolutely relies upon the diversity of its messengers. Different people listen to different forms of words, different styles of messaging, etc. The more, the better.

It’s good to know that our work is appreciated and helping. Working together as a community is essential for progress, so it was nice to see this question and response from someone we respect a great deal.

We have said many times before effective advocacy efforts are just as important as the research itself. Professional advocacy has the potential to increase public support and funding, paving the way for the arrival of rejuvenation biotechnology. In the past decade or so, advocacy has mostly been left to volunteers and people such as Dr. de Grey.

Popular causes attract celebrities, public support, funding and investment; if we want a revolution in medicine and how we treat aging, then we must popularize the movement. There has been a serious shortage of full-time and organized advocacy; therefore, we decided to create LEAF to support groups like the SRF, advocate to popularize the cause, and help to raise much-needed funds for research efforts. We are only able to do this thanks to the support of the community, and we are extremely grateful to our Lifespan Heroes for helping us to do the work we do.

Aside from funding, what do you consider to be a burden or delay for your type of research?

Nothing. Seriously, nothing at all. We have the plan, and we have the people. It’s all about enabling those people by giving them the resources to get on with the job.

Indeed, funding for research is one of the four major bottlenecks slowing down the development of therapies that address the aging processes. The more funding the field gets, the more projects can be launched, the sooner breakthroughs can potentially happen, and the greater the benefits will likely be for all of us.

Is there anything new you are able to say about the breaking of cross-links in the extracellular matrix?

Absolutely. Short story, we now have a bunch of glucosepane-breaking enzymes, and we are within a few months of spinning the work out into a startup.

A suspected cause of degenerative aging is the accumulation of sugary metabolic wastes known as advanced glycation end-products (AGEs). These are wastes that are, in some cases, hard for our metabolism to break down fast enough or even at all. Some types, such as glucosepane, can form cross-links, gumming together important proteins such as those making up the supporting extracellular matrix scaffold.

The properties of elastic tissues (skin and the blood vessel walls) derive from the particular structure of the extracellular matrix, and cross-links degrade that structure, preventing it from functioning correctly. AGEs’ presence contributes to blood vessel stiffening with age, and it is implicated in hypertension and diabetes.

That SRF now has candidate enzymes is very significant because it means that there are now potential ways to remove these crosslinks from our tissues. There are many types of crosslinks, and we already know of compounds and drugs that can break other kind of crosslinks; the major problem is glucosepane, as it lasts a very long time, and, so far, nothing is known to remove it. Given that other types of crosslinks can be removed, Dr. de Grey rightly thought that there must be ways to remove (cleave) glucosepane from tissues; now, it seems that we are a step closer to that potentially becoming a reality.

If the SRF is successful in finding ways to break glucosepane crosslinks, this has huge implications for diabetes, hypertension and aging. It is great to hear that the organization is now reaching the point at which it is almost time to develop this as a therapy by creating a startup company.

It seems likely that artificial intelligence will be a necessary tool in order to reach longevity escape velocity. I was wondering how much of a role does artificial intelligence play in your research? Is this something you devote many resources to?

We don’t, but that is because other major players in this field (and good friends of mine), such as Alex Zhavoronkov and Kristen Fortney, are doing it so well already (with Insilico Med and BioAge, respectively). Check out the BioData West conference that will occur in SF a couple of days before our Undoing Aging conference in Berlin; I will be chairing a session on this.

We believe that the application of AI and, in particular, machine learning will prove to be a very valuable tool for research in the coming years. Such systems are ideally suited for high-throughput, laborious tasks that also require high attention to detail and would take humans a long time to do. Drug discovery, image analysis and many more tasks in the lab could potentially be automated, saving time and freeing up researchers to work on other critical tasks.

We are proud to have hosted the MouseAge project this year, which is an AI-based visual aging biomarker application that helps researchers determine the age of mice without the use of harmful tests. In a few months, researchers will be able to use the MouseAge application in the lab to help speed research progress up. This is just one example of how AI can be used in aging research and how the community helped to make it happen.

Given current funding, how far away from robust mouse rejuvenation do you think you are?

My estimate is 5-7 years, but that’s not quite “given current funding”. My overoptimism in saying “10 years” 13 years ago consisted entirely of overoptimism about funding – the science itself has not thrown up any nasty surprises whatsoever – but, nonetheless, I am quite optimistic as of now about funding, simply because the progress we have made has led to a whole new world of startups (including spinoffs from the SENS Research Foundation) and investors, so it’s not only philanthropy anymore. Plus, the increase in overall credibility of the approach is also helping to nurture the philanthropic side. We are still struggling, that’s for sure, but I’m feeling a lot surer that the funding drought’s days are numbered than I felt even two or three years ago.

Robust mouse rejuvenation (RMR) has long been a goal for the SENS Research Foundation, going back to when the SENS approach was initially proposed. RMR was originally outlined as being able to demonstrate and replicate SENS to double the remaining life expectancy of an already aged mouse. This would not mean the first RMR would be a total implementation of all the SENS approaches or that rejuvenation would need to be absolute; it would be a first pass to demonstrate the viability of multiple SENS approaches combined to produce robust results.

Being able to achieve a first-pass RMR could do much to convince academia that the repair approach to aging is plausible and attract more funding and interest in the approach. While RMR working in mice may not sound that exciting, it has huge implications for the field and potentially the rate of funding and progress.

How confident are you still in your previous prediction that humans will be able to control aging by 2029?

I think we’ve slipped a few years, entirely because of lack of funding. The tipping point will be when results in mice convince a critical mass of my curmudgeonly, reputation-protecting expert colleagues that rejuvenation will eventually work, such that they start to feel able to say so publicly. I think that’s on the order of five years away.

We think that the tipping point could well be if senolytics have the same result in humans as they have in mice. Enhanced tissue repair and regeneration in older people would be a very strong case for the repair approach to aging and almost certain to convince the academics sitting on the fence.

Certainly, if AGE breakers could be demonstrated to work in humans, this would also go a long way towards not only convincing academia but also grabbing public interest. Removing AGEs from the skin may potentially reverse wrinkles, for example, and restore skin elasticity, offering a very visual demonstration of repair being plausible.

There is almost certainly going to be a tipping point at which the bulk of academic and public support swings in favour of a repair approach to aging; the only question is when? Well, the sooner the basic science can be done and moved to translational research, the sooner we can all potentially benefit from these technologies. This makes supporting both the research and advocacy of rejuvenation biotechnology very important for progress.

 

About Dr. Aubrey de Grey

Dr. Aubrey de Grey is a biomedical gerontologist based in Cambridge, UK and Mountain View, California, USA, and is the Chief Science Officer of SENS Research Foundation, a California-based 501(c)(3) charity dedicated to combating the aging process. He is also Editor-in-Chief of Rejuvenation Research, the world’s highest-impact peer-reviewed journal focused on intervention in aging. He received his BA and Ph.D. from the University of Cambridge in 1985 and 2000 respectively. His original field was computer science, and he did research in the private sector for six years in the area of software verification before switching to biogerontology in the mid-1990s. His research interests encompass the characterisation of all the accumulating and eventually pathogenic molecular and cellular side-effects of metabolism (“damage”) that constitute mammalian aging and the design of interventions to repair and/or obviate that damage. He has developed a possibly comprehensive plan for such repair, termed Strategies for Engineered Negligible Senescence (SENS), which breaks aging down into seven major classes of damage and identifies detailed approaches to addressing each one. A key aspect of SENS is that it can potentially extend healthy lifespan without limit, even though these repair processes will probably never be perfect, as the repair only needs to approach perfection rapidly enough to keep the overall level of damage below pathogenic levels. Dr. de Grey has termed this required rate of improvement of repair therapies “longevity escape velocity”. Dr. de Grey is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the editorial and scientific advisory boards of numerous journals and organisations.

About Steve Hill

As a scientific writer and a devoted advocate of healthy longevity technologies, Steve has provided the community with multiple educational articles, interviews, and podcasts, helping the general public to better understand aging and the means to modify its dynamics. His materials can be found at H+ Magazine, Longevity Reporter, Psychology Today, and Singularity Weblog. He is a co-author of the book Aging Prevention for All – a guide for the general public exploring evidence-based means to extend healthy life (in press).

About LIFE EXTENSION ADVOCACY FOUNDATION (LEAF)

In 2014, the Life Extension Advocacy Foundation was established as a 501(c)(3) non-profit organization dedicated to promoting increased healthy human lifespan through fiscally sponsoring longevity research projects and raising awareness regarding the societal benefits of life extension. In 2015 they launched Lifespan.io, the first nonprofit crowdfunding platform focused on the biomedical research of aging.

They believe that this will enable the general public to influence the pace of research directly. To date they have successfully supported four research projects aimed at investigating different processes of aging and developing therapies to treat age-related diseases.

The LEAF team organizes educational events, takes part in different public and scientific conferences, and actively engages with the public on social media in order to help disseminate this crucial information. They initiate public dialogue aimed at regulatory improvement in the fields related to rejuvenation biotechnology.

Shibuya Mirai, The First AI Bot Granted Official Residency – Article by B.J. Murphy

Shibuya Mirai, The First AI Bot Granted Official Residency – Article by B.J. Murphy

B.J. Murphy


A few days ago, an artificial intelligence (AI) bot was granted official residency in Shibuya, a Tokyo ward with a population of around 224,000 people. The AI bot’s name is “Shibuya Mirai,” which takes the form of a seven-year-old boy, and serves as a chatbot on the popular Line messaging app.

According to Japan Today:

“Tokyo’s Shibuya Ward, an area popular with fashion-conscious young people, has given the character his own special residence certificate. This makes him Japan’s first, and maybe the world’s first, artificial intelligence bot to be granted a place on a real-life local registry.”

Mirai, whose name translates to “future,” is part of a project aimed at making the local government more familiar and accessible to locals, according to the ward, and is designed to listen to the opinions of Shibuya residents.

Image source: Shibuya City

Nearly two weeks ago, Sophia, a humanoid robot designed by Hong Kong company Hanson Robotics, was granted citizenship by the Kingdom of Saudi Arabia, becoming the world’s first humanoid robot to ever be granted such an honor. And just as the U.S. Transhumanist Party supported Sophia’s citizenship recognition, we also would like to congratulate Mirai as well, along with the Shibuya Ward and Microsoft in their joint-development of the AI bot.

In accordance with the U.S. Transhumanist Party Constitution Article III, Section IX [Adopted by a vote of the members during February 16-22, 2017]:

“The United States Transhumanist Party supports all emerging technologies that have the potential to improve the human condition – including but not limited to autonomous vehicles, electric vehicles, economical solar power, safe nuclear power, hydroelectricity, geothermal power, applications for the sharing of durable goods, artificial intelligence, biotechnology, nanotechnology, robotics, rapid transit, 3D printing, vertical farming, electronic devices to detect and respond to trauma, and beneficial genetic modification of plants, animals, and human beings.”

While we recognize, to the best of our ability, that Mirai is still nowhere close to being deemed sentient – rather operates as a narrow AI – we equally recognize the significance of granting an AI real-life residency during a time when artificial general intelligence (AGI) research is at an all-time high.

It has been predicted that an AGI could possibly emerge within the next decade or so. Preparing the framework for both AI and robot rights in our near future is absolutely crucial. We are hopeful that, with Mirai being granted official residency, we are moving in a positive direction where all sentient lifeforms of the future (whether they be human, robot, AI, or otherwise) will be able to live and strive together peacefully.

B.J. Murphy is Director of Social Media for the U.S. Transhumanist Party.

Interview with Dr. Akihiro Kubota by Ryan Starr

Interview with Dr. Akihiro Kubota by Ryan Starr

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Ryan Starr
Akihiro Kubota


Preface: Art gives birth to scientific innovation.

In an effort to learn more about the historical origins of transhumanism and posthumanism, R. Nicholas Starr began a journey to look at the many topics popular within those communities and retraced them back to art. To continue the research he began to reach out to the artists and scientists at the forefront of exploring this relationship. While he continues to prepare his research for publication, he has decided to release the transcripts from these interviews in hopes to spark conversation and gather even more insight into how the creative mind has shaped our scientific world as we move past the limits of the human body.

R. Nicholas Starr is a multimedia artist, biohacker, researcher, and theorist. With an education in signals intelligence from the United States Air Force, and 20 years of experience creating art and performing music in the U.S. and abroad, he has become a unique voice for the U.S. Transhumanist Movement and American policy.

The second in this series is an interview with Dr. Akihiro Kubota from the Tama Art University, Tokyo, Japan. A special thanks to Phil Harry who assisted with the translations.

Quick note and disclaimer from the translator:

I am not a trained professional translator, and this is my first time translating something of this scope, so it may not be a perfect interpretation of the original author’s intended meaning.

 

–BEGIN QUESTIONS–

 

What are the critical processes required to create an artificial intelligence program that turns data into art?

重要なのは、AIが作品をつくれるか、ではなく、AIが鑑賞できるか、だと思っています。今日の美術にとって重要なのは、作品そのものよりもその文脈なので、鑑賞するということは、作品に多様な文脈を接続することで、それは現在のAIのフレームワーク例えば機械学習/強化学習でも可能だと考えています。

I think what’s crucial is not necessarily whether or not AI can make art, but rather whether or not AI can appreciate art. In art that’s being made today, what is even more important than the work itself, is the context of the work. In this sense artistic appreciation requires making connections between the various contexts of a work. I think the framework of modern AI, (through machine learning and reinforcement learning, etc.) allows for this to be possible.

 

How would the progression from assisted AI to autonomous AI impact AI’s artistic power?

文脈は、環境と知覚に依存するので、人間以外の知覚から生まれる新たな文脈はが、新たな芸術を生み出すでしょう。AIが人間のための芸術をつくることよりも、人間がAIのための芸術をつくることつくれるかがより重要な問題だと思います。

Because context relies heavily on environment and perception, the new contexts that arise from the perception of an entity that is other than human should lead naturally to the creation of new types of art. Rather than AI creating art for the sake of humans, I think a more important problem is the idea of humans creating art for the sake of AI, and whether or not that is possible.

 

By continuing research in AI-created art, what conclusions can we draw about sentience and sapience?

ノラ・ハラリが「ホモ・デウス」で予測するように、人間が「無用」になった時に、新たな時代が始まるのだと思います。「労働」や「学校」という概念から自由になりイヴァン・イリイチが主張したように美術や芸術の本来の役割が復活するでしょう。それこそが、人間本来の姿なのかもしれません。「ホモ・デウス」の時代の「無用層」の芸術、そこに人間の未来があります。

As Yuval Noah Harari predicts in Homo Deus, I think the point at which humans become “useless” will be the beginning of a new age. Once we are freed from the concepts of “school” and “labor” (as asserted by Ivan Illich), the original, essential role of the arts could make a revival – in effect, a revival of man’s essential nature. In the art of the “useless class”, proposed by Homo Deus’s new age – that is where the future of mankind resides.

 

Artificial intelligence is a concept that has its roots in literature and mythology. Now that AI can create its own art, have we created a mutual feedback loop?

ハラリの主張の重要なポイントは、「意識」と「知性」の分離が起こることですgreat decouplingAIで「意識」を作ろうとするのは無駄なことです。むしろ「知性」を「意識」から解放することで、「知性」を自由にすることが、大きな可能性を生み出します。擬人化という牢屋から知性を出してあげましょう。

The crucial point of Harari’s claim is the separation of “consciousness” and “intelligence” (the “Great Decoupling”) – the idea being that it is futile to attempt to create consciousness in AI. Rather, by unleashing the concept of intelligence from consciousness, this liberation will bring forth great possibilities. In this way I think we should reconsider how we think of intelligence and set it free from the confines of personification and anthropomorphization.

 

Is it possible to amplify or modify this feedback loop by interfacing AI directly with the human body?

人間が拡張することと、知性が自由になることは、本質的に無関係です。人間には理解できない知性があることを前提に、人は生きていかなければなりません。人間がAIの知性の進化を阻害することこそを懸念しなければなりません。

The advancement of mankind and the liberation of intelligence are essentially unrelated. People are going to have to get comfortable living under the assumption that there are types of intelligence that we can’t comprehend. Instead, what we should concern ourselves with is whether or not we are actively inhibiting the evolution of AI.

 

You previously acknowledged that the human body has the ability to adapt to, and capitalize on, a new bio-interface. With the current interest in neural lace and other cybernetic technology, how do you see humanity evolving after a several generations of use?

そうした中で、人間は人間としてその可能性を拡げていくことができるのか。僕は、人間はそれだけの柔軟性と可塑性を有していると思います。機械を人間に適合するのでなく、人間が機械に適合しようとすることで、その可能性を拡げていくことこそが、人間の未来を形作っていきます。

In addition to that, I wonder about the human capacity to expand on this ability. As it is, humans alone are endowed with the necessary flexibility and plasticity to do so. Rather than machines conforming to the needs of humans, by attempting to adapt to the machines, and expand our own capabilities, we will shape the future of mankind.

 

Do you predict our interactions changing with planet and space as a result?

今日の人間の一番の特徴は、個人の能力にあるのではなく、その数人口にあります。人間の「量」こそがポイントです。そういった意味からは、人間の「量」が地球自体に大きな影響を与えることは、不可避だと思います。地球の有限性が      顕在化したのです。

The greatest trait humans possess today is not our individual abilities, but our collective abilities. The emphasis here being on our “quantity” – meaning that the effect we collectively have on the very planet we live on is an inevitability. And we are beginning to see that the limits of our planet are being actualized.

 

A significant amount of your work focuses on satellite-based data collection. Why do you prefer this point of view?

芸術も科学と同様、常にフロンティア遠くを目指しています。パーソナルなテクノロジーで衛星を作れるようになった今、なぜそれを使って芸術をやらないのかARTSATプロジェクトは、極めて当たり前の行為芸術活動だと思っています。

Art and Science alike are on the cutting edge of new horizons, and constantly reaching into distant frontiers. Living in an age where we have the capabilities to create satellites using “personal technology”, using them to create art seems like a natural progression. So for me, the ARTSAT project is just an extremely obvious artistic endeavour to undertake.

 

You stated that the DESPATCH probe “composes and encodes poetry reflecting not only the sensor data but the artist’s subconscious personality”. Did the sculptural shape of DESPATCH influence the data collected and final tonal output?

最初に書いたように、芸術にとって重要なのは作品をつくることではなく、作品を鑑賞解釈することです。同じデータでも、10人の人が鑑賞すれば、そこの10個の異なる作品が生まれるのです。たとえ、受信データが単なるノイズであったとしても。

As I said before, when it comes to art, the most important thing is not the creation of a piece of artwork, but instead the aesthetic appreciation or the interpretation of the piece. In terms of DESPATCH, if you had ten different people looking at the same data, they would all interpret it in different ways, and thus give rise to ten separate pieces. And this is true even if the transmission signal’s data is merely background noise.

 

How can the average person create their own scientific lens to view and create art?

政治や経済、マスメディアがつくりだしている、虚構の人間観にとらわれず、人間本来の姿や可能性に気がつくことが必要です。労働から解放され、無用な存在になり、ゴーギャンのように『我々はどこから来たのか 我々は何者か 我々はどこへ行くのか』と問うことは、誰にでもできますし、誰もが行うべきことなのだと思います。そこには、制度としての「科学」も「芸術」も不要です。必要なのは「理性」と「知性」なのです。「感情」を偏重する今日の社会の危険性は、すでに多くの人が気づいていることだと思います。何とかしなければなりません。

Systems of government, economies, mass media, etc. – these are all man-made concepts. It is essential that we not be seized by these fabricated human perspectives in order to realize our essential nature and reach the limits of human potential. Once we are freed from the restraints of human toil and begin to occupy Harari’s “useless” existence, I think it will be possible and necessary for all people to wrestle with the existential questions put forth by Gaugin in “Where do we come from? What are we? And where are we going?”. It is in this space that the systems known as “science” and “art” will become unnecessary. What is important are “reason” and “intelligence”. I believe many people are already realizing the potential danger of overemphasizing the importance of “emotion” in today’s society, and I think we need to do something about that.

 

Ryan Starr (R. Nicholas Starr) is the is the leader of the Transhumanist Party of Colorado and founder of the Transhumanists of the Sierras

See Dr. Akihiro Kubota’s page of teaching achievements and activities here.

21-Day Exposure Period for Platform Vote #6

21-Day Exposure Period for Platform Vote #6

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Gennady Stolyarov II


For its upcoming sixth Platform vote, the U.S. Transhumanist Party has receive a large volume of suggestions from members during the past four months. This exposure period is intended to encompass as many of these suggestions as possible. A vote will be scheduled on some or all of these items once they have been exposed for at least 21 days. For each item, a 7-day voting period is expected to be opened at the earliest at 12:01 a.m. on Saturday, November 11, 2017.

During the exposure period, please post your comments on this thread. If you post comments intended to be considered in voting and/or amending any of these planks in any other electronic medium, please note that you thereby give your consent to have your comments reproduced with attribution or linked within this discussion thread, in order to direct members’ attention and consideration to them.

After the exposure period, a 7-day electronic voting period will occur. Instructions for electronic voting will be sent to members of the U.S. Transhumanist Party via e-mail at that time. All individuals who are members of the U.S. Transhumanist Party as of the end of the exposure period and who have expressed agreement with its three Core Ideals will be eligible to vote thereafter. You can still vote if you become a member during the exposure period, so please apply here if you are interested. During the 7-day electronic voting period, you will still be able to become a member – but you will only be able to vote in subsequent elections, since we seek for voting on any given issue to be done by those members who have had an opportunity to thoroughly consider that issue and be involved in deliberations regarding it.

Electronic voting will be conducted by a ranked-preference method if more than a single option is presented for the wording of a particular plank or segment of a plank. Members will be able to rank-order their preferred selections on each individual Platform Section. The original text of each Section will be available for selection, as well as any reasonable amendments proposed by any member. Leadership of the Transhumanist Party reserves the right to edit any proposed amendment for correctness of spelling and grammar only – but not with regard to the substance, unless the person proposing the amendment requests or consents to a substantive edit. “No Section of this sort” will also be a choice, and any Section where a majority of votes favors this option will be not be adopted. Members will also be able to abstain from voting on any given Section.

The ranked-preference method has the advantage of eliminating a “winner-take-all” or “first-past-the-post” mentality and preventing people from being channeled into voting for sub-optimal choices (in their view) just because they fear an even less palatable alternative prevailing. Within the ranked-preference methodology, if no option obtains a clear majority as voters’ first choice, the option having the fewest first-choice votes is eliminated from consideration, and all those who voted for that option will have their votes assigned to their second-choice options. This process of elimination continues until one particular option has a clear majority of votes.

The Transhumanist Party encourages all members to participate in this process and for other transhumanists to sign up for membership during the exposure period. 

The Section titles below are provisional and will be replaced with official numbers for each plank that is adopted. The Section titles are informational only and will not be included in the adopted versions of the platform planks.


Section E6-A. Minimum Timeframe for Voting on a Bill

Option E6-A-1. [Based on Proposal by Martin van der Kroon]

The United States Transhumanist Party supports efforts to create a reasonable minimum timeframe between the proposal of a bill and the voting procedure. To ensure a reasonable timeframe is proportional to the number of pages of a proposed bill, a time period per each specified amount of pages could be adopted. For example, and without committing to specific numerical magnitudes, a 24-hour period within a working week per every 20 pages could be adopted to ensure all member of Congress involved have sufficient time to read through and study a proposed bill’s implications. Such measures would prevent a bill from being introduced shortly before the voting process. They would also have the added side effect that proposals might become more concise, as the length of a bill would influence the consideration time.

[The question will allow members to select one or none of the ancillary provisions below, with any measure receiving a majority of the votes being included in the ultimately adopted plank. The ancillary provisions are compatible with each of the main options above.]

Ancillary Provision Option E6-A-i. [Based on Proposal by Martin van der Kroon]  In addition to this, after the proposal has been submitted, no change may be made to the proposal to prevent changing the substance of a proposal.

Ancillary Provision Option E6-A-ii. [Based on Proposal by Gennady Stolyarov II] In addition to this, after the proposal has been submitted, any amendments must be explicitly discussed in a public forum with the same degree of thorough consideration and same rules pertaining to the timeframe of consideration as allowed for the original proposal.

 

Section E6-B. Fully Informed Juries

Option E6-B-1. [Based on Proposal by Martin van der Kroon]

The United States Transhumanist Party supports efforts to ensure a jury is fully informed on its rights and responsibilities, including jury nullification. The United States Transhumanist Party also supports efforts to prevent false claims being made regarding the rights and responsibilities of the jury.

 

Section E6-C. Elimination of Stationary Nuclear Stockpile

Option E6-C-1. [Based on Proposal by Martin van der Kroon]

As an intermediate step toward the goal of complete nuclear disarmament and a potential pragmatic compromise in any future negotiations for disarmament, the United States Transhumanist Party supports efforts to significantly reduce the United States nuclear stockpile, and to replace or transfer a small part (between 1 percent and 10 percent) of this stockpile, to mobile nuclear platforms such as submarines. An enemy may currently target the stationary nuclear bombs directly. Having a largely hidden mobile fleet of nuclear bombs would render it much more difficult for any enemy to target the nuclear arsenal, while still maintaining the nuclear deterrent option in sufficient capacity. This would further have the effect of lowering the budget required to maintain the nuclear stockpile, as it could be drastically downsized.

 

Section E6-D. Legalization of Prostitution

Option E6-D-1. [Based on Proposal by Martin van der Kroon]

The United States Transhumanist Party supports the right for individuals to have autonomy over, and utilize their bodies to earn money, including through activities such as prostitution, as long as such activities arise from a person’s own free will (e.g., not under duress), and the person is not endangering the health or well-being of others.

Legalization would give those who wish to engage in prostitution the safety and protection of the law – for example, so that they may report abuse and would be prone to being exploited. It would also open the possibility for such individuals to unionize if they wish to do so. Furthermore, legalization would decrease government spending on what is ultimately a ‘moral crusade’.

Option E6-D-2. [Based on Proposal by Martin van der Kroon, with Added Wording by Ajay Davis]

The United States Transhumanist Party supports the right for individuals to have autonomy over, and utilize their bodies to earn money, including through activities such as prostitution, as long as such activities arise from a person’s own free will (e.g., not under duress), and the person is not endangering the health or well-being of others, including but not limited to the communication of sexually transmissible diseases.

Legalization would give those who wish to engage in prostitution the safety and protection of the law – for example, so that they may report abuse and would be prone to being exploited. It would also open the possibility for such individuals to unionize if they wish to do so. Furthermore, legalization would decrease government spending on what is ultimately a ‘moral crusade’.

[The question will allow members to select one or none of the ancillary provisions below, with any measure receiving a majority of the votes being included in the ultimately adopted plankThe ancillary provisions are compatible with each of the main options above.]

Ancillary Provision E6-D-i. [Based on Proposal by Ryan Starr]

However, the United States Transhumanist Party unequivocally condemns any manner of human trafficking, child exploitation, and other abuse that involves a violation of the autonomy and consent of any individual. The legalization of prostitution should be combined with stronger efforts to combat these dangerous and exploitative practices.

Ancillary Provision E6-D-ii. [Based on Proposal by Martin van der Kroon]

The legalization of prostitution could furthermore enable more effective action against human trafficking and involuntary exploitation, as, when prostitution is legalized, employees in this industry would become subject to the protections of the law. Legalization would help focus resources on combating the trafficking of humans rather than catching workers who chose this profession voluntarily.

 

Section E6-E. Public Records of Official Statements

Option E6-E-1. [Based on Proposal by Ryan Starr, with Clarifications Suggested by Martin van der Kroon]

The United States Transhumanist Party holds that any statement made by an elected official and/or public servant to members of the public in a public forum, and available to be heard, read, or otherwise understood in a public setting, physical or digital, should be considered a part of the public record and treated as an official statement of their office and position.

Option E6-E-2. [Based on Proposal by Ryan Starr, with Further Clarifications Regarding the Capacity in Which the Official Acts]

The United States Transhumanist Party holds that any statement made by an elected official and/or public servant to members of the public in a public forum as part of that official’s or public servant’s job duties, and available to be heard, read, or otherwise understood in a public setting, physical or digital, should be considered a part of the public record and treated as an official statement of their office and position. This requirement does not extend to statements made by an elected official and/or public servant in the capacity of a private citizen or in the expression of a personal opinion or other position unrelated to the exercise of the official’s or public servant’s job duties.

 

Section E6-F. Artificial Intelligence System to Analyze Risk of Proposed Legislation

Option E6-F-1. [Based on Proposal by Ryan Starr]

The United States Transhumanist Party holds that state and federal governments should establish an artificial intelligence (AI) analysis system for measuring risk of proposed legislation. Such a system could provide an impartial look at what legislation could cause harm or unintended consequences. Submitted policies would receive a score from 0 to 100, and the AI system would state what possible negative impacts may result. This system should be publicly accessible for submissions and for security audit. This is not intended to create or enact laws, but simply to serve as a tool to measure risk versus reward.

Option E6-F-2. [Based on Proposal by Ryan Starr, with Added Wording by Daniel Yeluashvili on Blocking Certain Laws]

The United States Transhumanist Party holds that state and federal governments should establish an artificial intelligence (AI) analysis system for measuring risk of proposed legislation. Such a system could provide an impartial look at what legislation could cause harm or unintended consequences. Submitted policies would receive a score from 0 to 100, and the AI system would state what possible negative impacts may result. This system should be publicly accessible for submissions and for security audit. This is not intended to create or enact laws, but simply to serve as a tool to measure risk versus reward. However, such an AI system should be used to block laws that have a 50% or greater probability of negatively affecting the majority of the population.

 

Section E6-G. Opposition to Partisan Determination of Voting Districts

Option E6-G-1. [Based on Proposal by Martin van der Kroon]

The United States Transhumanist Party strongly opposes the possibility for any political party to determine the boundaries and borders of any voting district. The United States Transhumanist Party supports measures that require any efforts to have the districts potentially redrawn, when necessary due to migration for example, to be left to an automated system such as an artificial intelligence (AI) designed for this task.

 

Section E6-H. Limitation of Presidential Authority over International Agreements

Option E6-H-1. [Based on Proposal by Martin van der Kroon]

The United States Transhumanist Party supports efforts to remove the possibility for a President to sign an international agreement among two or more nations by executive order. This would prevent a President from engaging in international affairs without support from the Congress, and likewise would make it more difficult to exit an international agreement, as support from Congress would need to exist in order for such an exit to occur. This would furthermore ensure that the United States becomes a more trustworthy nation in the eyes of the international community.

 

Section E6-I. International or World Passport

Option E6-I-1. [Based on Proposal by Martin van der Kroon]

The United States Transhumanist Party supports efforts to create a framework for an international or world passport. This framework could, for example, be administered through the United Nations, and the passport could be valid only for those countries who have proven to meet the standards, set by participating countries, required to ensure safety. Given that the European Union has an ID valid within its borders, and the United States has a similar agreement with Canada, imagining these forms of identification being combined shows that a world passport is not a farfetched or alien idea.

 

Section E6-J. Registration Chip for New Firearms

Option E6-J-1. [Based on Proposal by Martin van der Kroon]

The United States Transhumanist Party supports efforts to mandate that new firearms will be produced with an embedded registration chip, as well as the registration number engraved on the firearm. The chip would have a registration number, a ‘trace online’ code, and a ‘lost or stolen’ code. The firearm would be accompanied by a physical and digital certificate of ownership with a registration number, the ‘trace online’ number, and the ‘lost or stolen’ number. The embedded chip would render it much harder to make the firearm untraceable. The number and codes involved would have to be unique identifiers.

When a firearm would be lost or stolen, the owner of the firearm and holder of the certificate would report the firearm to the authorities as lost or stolen using the ‘lost or stolen’ number. The intent of having a separate reporting number is to ensure that, in the event that a firearm is stolen or taken without consent, the offender cannot report the firearm as stolen, or as found again. When a firearm owner suspects the firearm is simply mislocated – for example, in the car or in the house, or perhaps taken by a family member, the owner could trace the firearm online via GPS on an online map, using the ‘trace online’ code. The ‘trace online’ code would never be revealed to law enforcement.

Law enforcement would have a device that can confirm the registration number of a firearm in close proximity, similar to contactless payments. On the other hand the detection range would be greater when a firearm has been reported lost or stolen by the owner of the firearm in question with the ‘lost and stolen’ number. A firearm that would not have been reported lost or stolen to law enforcement by the owner of the firearm with the ‘lost or stolen’ number would not be traceable from a greater distance by law enforcement.

This would ensure the privacy, safety, and peace of mind of firearm owners who might otherwise feel law enforcement would trace firearms without legal justification. At the same time, this measure would decrease the probability of stolen firearms never being found, and possibly ending in the hands of people with ill intent.

 

Section E6-K. Public Civil-Rights Prosecutor

Option E6-K-1. [Based on Proposal by Ryan Starr]

The United States Transhumanist Party supports the creation of an office of a Public Civil-Rights Prosecutor. Our current justice system is flawed. Only people with substantial wealth can afford lawyers to take legal action against those who attack a person’s rights. While there are organizations like the American Civil Liberties Union (ACLU), which offer help for some cases, their ability to do so is severely limited and typically non-existent in the lower courts. A Public Civil-Rights Prosecutor’s office will help guarantee that, no matter who a person is or the position of the offending party, a person’s rights cannot be assailed without consequence.

 

Section E6-L. Lowering Military Spending

Option E6-L-1. [Based on Proposal by John M.]

The United States Transhumanist Party supports lowering spending by the Department of Defense and the U.S. Military, which amounts to hundreds of billions of dollars per year and includes unchecked wastefulness. Reducing military spending would free up money for more important goals, such as curing disease, which collectively kills many more people than military conflict or war by an exponential degree.

 

Section E6-M. Accountability for Use of Federal Grants

Option E6-M-1. [Based on Proposal by Martin van der Kroon]

The United States Transhumanist Party supports efforts to hold institutions, corporations, and states accountable for usage of federal money with a specific intended purpose. When an entity has been granted any form of funding with a specifically intended purpose, such as disaster relief or specific educational funds, and these funds are misappropriated or used for other purposes well outside of the scope of what they were intended for, the entity in question ought to restitute the funding that was made available.

 

Section E6-N. Increased Funding for the National Institutes of Health

Option E6-N-1. [Based on Proposal by John Marlowe]

The United States Transhumanist Party supports increases in the budget for the National Institutes of Health (NIH). Numerous biotech CEOs have recently made the case to increase the NIH budget, because the NIH conducts research that their companies would not be able to invest in, as investments not leading directly to a product would affect the bottom line. 33% of all the publications from NIH research are cited in corporate patents, so it stimulates new product development. A major driver for economic progress and reducing the suffering of those in pain, the NIH is essentially a public charity that brings us into the future. Whether one supports limited or expansive government, the NIH does not seek to regulate anything nor impose laws on anyone. It exclusively conducts medical research to help the sick.

Option E6-N-2. [Based on Proposal by John Marlowe, with Modification to Require Offsetting Decreases in Military Spending]

The United States Transhumanist Party supports increases in the budget for the National Institutes of Health (NIH), provided that such increases are offset by equivalent or greater decreases in military spending. Numerous biotech CEOs have recently made the case to increase the NIH budget, because the NIH conducts research that their companies would not be able to invest in, as investments not leading directly to a product would affect the bottom line. 33% of all the publications from NIH research are cited in corporate patents, so it stimulates new product development. A major driver for economic progress and reducing the suffering of those in pain, the NIH is essentially a public charity that brings us into the future. Whether one supports limited or expansive government, the NIH does not seek to regulate anything nor impose laws on anyone. It exclusively conducts medical research to help the sick.

 

Section E6-O. Reinstatement of Voting Rights to Felons Who Have Served Their Punishment

Option E6-O-1. [Based on Proposal by Martin van der Kroon]

The U.S. Transhumanist Party supports efforts to reinstate the rights to vote for convicted felons who have received and served their punishment, in order to present them the opportunity to participate in society as otherwise normal citizens.

 

Section E6-P. Repeal of FDA Approval Requirements for Drug Tests on Willing Patients

Option E6-P-1. [Based on Proposal by Gennady Stolyarov II]

The United States Transhumanist Party supports repealing the current requirement in the United States that drugs or treatments may not be used, even on willing patients, unless approval for such drugs or treatments is received from the Food and Drug Administration. Such requirements are a profound violation of patient sovereignty; a person who is terminally ill is unable to choose to take a risk on an unapproved drug or treatment unless this person is fortunate enough to participate in a clinical trial. Even then, once the clinical trial ends, the treatment must be discontinued, even if it was actually successful at prolonging the person’s life. This is not only profoundly tragic, but morally unconscionable as well. The most critical reform needed is to allow unapproved drugs and treatments to be marketed and consumed. If the FDA wishes to strongly differentiate between approved and unapproved treatments, then a strongly worded warning label could be required for unapproved treatments, and patients could even be required to sign a consent form stating that they have been informed of the risks of an unapproved treatment. This reform to directly extend many lives and to redress a moral travesty should be the top political priority of advocates of indefinite life extension. Over the coming decades, its effect will be to allow cutting-edge treatments to reach a market sooner and thus to enable data about those treatments’ effects to be gathered more quickly and reliably. Because many treatments take 10-15 years to receive FDA approval, this reform could by itself speed up the real-world advent of indefinite life extension by over a decade.

 

Section E6-Q. Abolition of Medical Licensing Protectionism

Option E6-Q-1. [Based on Proposal by Gennady Stolyarov II]

The United States Transhumanist Party supports efforts to increase opportunities for entry into the medical profession. The current system for licensing doctors is highly monopolistic and protectionist – the result of efforts by the American Medical Association in the early 20th century to limit entry into the profession in order to artificially boost incomes for its members. The medical system suffers today from too few doctors and thus vastly inflated patient costs and unacceptable waiting times for appointments. Instead of prohibiting the practice of medicine by all except a select few who have completed an extremely rigorous and cost-prohibitive formal medical schooling, governments in the Western world should allow the market to determine different tiers of medical care for which competing private certifications would emerge. For the most specialized and intricate tasks, high standards of certification would continue to exist, and a practitioner’s credentials and reputation would remain absolutely essential to convincing consumers to put their lives in that practitioner’s hands. But, with regard to routine medical care (e.g., annual check-ups, vaccinations, basic wound treatment), it is not necessary to receive attention from a person with a full-fledged medical degree. Furthermore, competition among certification providers would increase quality of training and lower its price, as well as accelerate the time needed to complete the training. Such a system would allow many more young medical professionals to practice without undertaking enormous debt or serving for years (if not decades) in roles that offer very little remuneration while entailing a great deal of subservience to the hierarchy of an established institution. Ultimately, without sufficient doctors to affordably deliver life-extending treatments when they become available, it would not be feasible to extend these treatments to the majority of people.

 

Section E6-R. Abolition of Ability to Re-Patent Generic Medicines and Devices

Option E6-R-1. [Based on Proposal by Gennady Stolyarov II]

The United States Transhumanist Party supports reforms to the patent system that prevent the re-patenting of drugs and medical devices, or the acquisition of any exclusive or monopoly rights over those drugs and devices, once they have become generic or entered the public domain. Appallingly, many pharmaceutical companies today attempt to re-patent drugs that have already entered the public domain, simply because the drugs have been discovered to have effects on a disease different from the one for which they were originally patented. The result of this is that the price of the re-patented drug often spikes by orders of magnitude compared to the price level during the period the drug was subject to competition. Only a vibrant and competitive market, where numerous medical providers can experiment with how to improve particular treatments or create new ones, can allow for the rate of progress needed for the people alive today to benefit from radical life extension.

 

Section E6-S. Reduction of Medical Patent Timeframes

Option E6-S-1. [Based on Proposal by Gennady Stolyarov II]

The United States Transhumanist Party supports reforms to reduce the lengths of times over which medical patents could be effective. Medical patents – in essence, legal grants of monopoly for limited periods of time – greatly inflate the cost of drugs and other treatments. Especially in today’s world of rapidly advancing biotechnology, a patent term of 20 years essentially means that no party other than the patent holder (or someone paying royalties to the patent holder) may innovate upon the patented medicine for a generation, all while the technological potential for such innovation becomes glaringly obvious. As much innovation consists of incremental improvements on what already exists, the lack of an ability to create derivative drugs and treatments that tweak current approaches implies that the entire medical field is, for some time, stuck at the first stages of a treatment’s evolution – with all of the expense and unreliability this entails. Even with shortened patent terms, the original developer of an innovation will still always benefit from a first-mover advantage, as it takes time for competitors to catch on. If the original developer can maintain high-quality service and demonstrate the ability to sell a safe product, then the brand-name advantage alone can secure a consistent revenue stream without the need for a patent monopoly.

 

Proposed Amendments to Existing Planks

Members will be given the option to either retain existing language of a plank or to adopt any of the listed proposed amendments. Ranked-preference voting will be conducted for any Section for which more than one amendment has been proposed. Members will also be able to abstain from each vote.

 1. Amendments to Section II on Anti-Bigotry to Encompass “Alt-Left” Groups

Current Version of Section II. The United States Transhumanist Party abhors all racism, nativism, xenophobia, and sexism. Accordingly, the United States Transhumanist Party condemns any hostile discrimination or legal restrictions on the basis of national origin, skin color, birthplace, ancestry, gender identity, or any manner of circumstantial attribute tied to a person’s lineage or accident of birth. Furthermore, the United States Transhumanist Party strongly opposes any efforts to close national borders, restrict immigration of peaceful individuals, or deny opportunities to individuals on the basis of ethnicity, race, or national origin. The United States Transhumanist Party unequivocally condemns all demagogues who seek to segregate individuals on the basis of national origin, race, or ethnicity. In particular, The United States Transhumanist Party opposes movements describing themselves as “white nationalism”, “America First”, “race realism”, and the “alt-right” – as well as the counterparts of those movements in other countries.

Amendment II-1. [Addition of New Paragraph on “Alt-Left” Movements, Reflecting Recommendation by Scott Jurgens]

The United States Transhumanist Party abhors all racism, nativism, xenophobia, and sexism. Accordingly, the United States Transhumanist Party condemns any hostile discrimination or legal restrictions on the basis of national origin, skin color, birthplace, ancestry, gender identity, or any manner of circumstantial attribute tied to a person’s lineage or accident of birth. Furthermore, the United States Transhumanist Party strongly opposes any efforts to close national borders, restrict immigration of peaceful individuals, or deny opportunities to individuals on the basis of ethnicity, race, or national origin. The United States Transhumanist Party unequivocally condemns all demagogues who seek to segregate individuals on the basis of national origin, race, or ethnicity. In particular, The United States Transhumanist Party opposes movements describing themselves as “white nationalism”, “America First”, “race realism”, and the “alt-right” – as well as the counterparts of those movements in other countries.

While opposing movements based on hostile discrimination on circumstantial attributes, the United States Transhumanist Party also condemns movements on the “alt-left” which attempt to stifle free speech, use violence to prevent the expression of “alt-right” or even non-left-wing sentiments, or promote retributive circumstantial discrimination, which should be rejected along with the original acts of circumstantial discrimination against which the “alt-left” is reacting. The United States Transhumanist Party unequivocally opposes the use of violence against lives and property and the disruption of the peaceful conduct of daily life by movements calling themselves “Antifa”, “By Any Means Necessary”, or “Black Lives Matter” – even as the United States Transhumanist Party remains strongly opposed to fascism and strongly supports efforts to protect black Americans and all other Americans from police brutality and all other forms of violence. It is imperative that only peaceful, rights-respecting tactics and reforms be used in the efforts to thwart fascism and prevent police brutality.

Amendment II-2. [Addition of New Paragraph on “Alt-Left” Movements, Reflecting Suggestions by B.J. Murphy to Include Individual Supporters and Emphasize the Right of Self-Defense]

The United States Transhumanist Party abhors all racism, nativism, xenophobia, and sexism. Accordingly, the United States Transhumanist Party condemns any hostile discrimination or legal restrictions on the basis of national origin, skin color, birthplace, ancestry, gender identity, or any manner of circumstantial attribute tied to a person’s lineage or accident of birth. Furthermore, the United States Transhumanist Party strongly opposes any efforts to close national borders, restrict immigration of peaceful individuals, or deny opportunities to individuals on the basis of ethnicity, race, or national origin. The United States Transhumanist Party unequivocally condemns all demagogues who seek to segregate individuals on the basis of national origin, race, or ethnicity. In particular, The United States Transhumanist Party opposes movements describing themselves as “white nationalism”, “America First”, “race realism”, and the “alt-right” – as well as the counterparts of those movements in other countries – and individual supporters of those movements.

While opposing movements based on hostile discrimination on circumstantial attributes, the United States Transhumanist Party also condemns movements on the “alt-left” which attempt to stifle free speech, use violence to prevent the expression of “alt-right” or even non-left-wing sentiments, or promote retributive circumstantial discrimination, which should be rejected along with the original acts of circumstantial discrimination against which the “alt-left” is reacting. The United States Transhumanist Party unequivocally opposes the use of violence against lives and property and the disruption of the peaceful conduct of daily life by movements calling themselves “Antifa”, “By Any Means Necessary”, or “Black Lives Matter” and by individual supporters of those movements – even as the United States Transhumanist Party remains strongly opposed to fascism and strongly supports efforts to protect black Americans and all other Americans from police brutality and all other forms of violence. It is imperative that only peaceful, rights-respecting tactics and reforms be used in the efforts to thwart fascism and prevent police brutality.

However, the United States Transhumanist Party also recognizes the difference between committing violence for the sake of violence and committing violence as a means of self-defense – especially against fascism – and therefore does not condemn purely defensive violence.

Amendment II-3. [Simplification, Reflecting Recommendation by Martin van der Kroon

The United States Transhumanist Party opposes any movement or group, and individual members of such movements or groups, that utilize and justify the use of violence, bullying, doxxing, intimidation, and other coercive or privacy-infringing tactics in a quest to force their goals or display dominance, regardless of political orientation, leaning, or ideology.

Amendment II-4. [Simplification, Reflecting Recommendation by Daniel Yeluashvili

The United States Transhumanist Party supports all acceptance, tolerance, and inclusivity of individuals and groups of all races, genders, classes, religions, creeds, and ideologies. Accordingly, the United States Transhumanist Party condemns any hostile discrimination or legal restrictions on the basis of national origin, skin color, birthplace, ancestry, gender identity, or any manner of circumstantial attribute tied to a person’s lineage or accident of birth. Furthermore, the United States Transhumanist Party strongly opposes any efforts to enforce said restrictions regardless of cause or motivation thereof. Additionally, any institution that uses violence, suppression of free speech, or other unconstitutional or otherwise illegal methods will be disavowed and condemned by the United States Transhumanist Party, with an efficient, non-violent alternative to said institution being offered to achieve its goals if they align with the Party’s interests.

 

2. Amendments to Section XVII on Abolition of the Electoral College

Current Version of Section XXVII. The United States Transhumanist Party advocates Constitutional reform to abolish the Electoral College in the United States Presidential elections and render the plurality of the popular vote the sole criterion for the election of President. While the original intent of the Electoral College as a deliberative body to check the passions of the poorly informed masses and potentially overturn the election of a demagogue may have been noble, the reality has not reflected this intention. Instead, the Electoral College has enabled votes from less cosmopolitan, less tolerant, more culturally ossified and monolithic areas of the country to disproportionately sway the outcome of Presidential elections, to the detriment of individual liberty and progress.

Amendment XXVII-1. [Removal of Last Sentence, Reflecting Recommendation by Scott Jurgens] The United States Transhumanist Party advocates Constitutional reform to abolish the Electoral College in the United States Presidential elections and render the plurality of the popular vote the sole criterion for the election of President. While the original intent of the Electoral College as a deliberative body to check the passions of the poorly informed masses and potentially overturn the election of a demagogue may have been noble, the reality has not reflected this intention.

Amendment XXVII-2. [Removal of Last Two Sentences, Reflecting Recommendation by Scott Jurgens] The United States Transhumanist Party advocates Constitutional reform to abolish the Electoral College in the United States Presidential elections and render the plurality of the popular vote the sole criterion for the election of President.

 

 3. Amendments to Section LIX on External Investigations of Law-Enforcement Misconduct

Current Version of Section LIX. The United States Transhumanist Party considers it important for impartial, objective investigations of alleged police and other law-enforcement misconduct to be pursued. While law-enforcement agencies should not be prohibited from internally investigating potential abuses within their own ranks, such investigations should never be considered exclusive or conclusive, and further external checks and accountability should be instituted. As part of providing such checks and accountability, investigations regarding police misconduct, criminal activity, felonies, and misdemeanors should, in addition to any internal investigation, also be investigated by a different source – for example, a different police department, or a district attorney for a different area assigned to lead the investigation. The intent of this requirement is to limit the possibility of favorably biased or preferential treatment of a member of a given law-enforcement agency by that person’s colleagues, and to restore confidence by the public that an investigation into police misconduct is done as objectively as possible.

Amendment LIX-1. [Replacement of Second-to-Last Sentence to Require a Civilian Investigating Organization, Based on Recommendation by Ryan Starr] The United States Transhumanist Party considers it important for impartial, objective investigations of alleged police and other law-enforcement misconduct to be pursued. While law-enforcement agencies should not be prohibited from internally investigating potential abuses within their own ranks, such investigations should never be considered exclusive or conclusive, and further external checks and accountability should be instituted. As part of providing such checks and accountability, investigations regarding misconduct, negligence, abuse, criminal activity, felonies, and misdemeanors allegedly committed by police, district attorneys, and judges, should, in addition to any internal investigation, also be conducted by a civilian organization outside the justice system. The intent of this requirement is to limit the possibility of favorably biased or preferential treatment of a member of a given law-enforcement agency by that person’s colleagues, and to restore confidence by the public that an investigation into police misconduct is done as objectively as possible.

Jim Mellon Announces Launch of New Book – Juvenescence: Investing in the Age of Longevity – Press Release by Biogerontology Research Foundation

Jim Mellon Announces Launch of New Book – Juvenescence: Investing in the Age of Longevity – Press Release by Biogerontology Research Foundation

Biogerontology Research Foundation


London, UK: Biogerontology Research Foundation Trustee Jim Mellon announces the publication of his newest book, Juvenescence: Investing in the Age of Longevity.

The book is a comprehensive summary of the emerging longevity industry, including profiles of longevity companies, investment opportunities, and aims to chart the major ideas of the geroscience’s thought-leaders and the vast implications this will have on economies and societies.

Often referred to as the British Warren Buffett, Billionaire Jim Mellon is well known for identifying major emerging trends before they become mainstream. Mellon made his wealth by investing in emerging markets throughout the 1990s. After many years of research and investing in the life science sector, Jim announced his vision for the emergence of the nascent longevity industry at Master Investor, one of the UK’s leading investor show in March of 2017, which was attended by over five thousand investors and entrepreneurs.

“The Biogerontology Research Foundation is proud to support what we feel will come to be seen as a landmark publication in the modern history of biogerontology. Jim has put an enormous amount of thought and effort into this new book, and has interviewed many of the field’s leading scientists in his research. The field of geroscience and the emerging longevity industry are both sure to prosper from very well-respected business personalities like Jim Mellon championing the longevity industry and projecting that it will become the world’s largest industry. Further, governments and policy makers should note the pressing need for a paradigm shift in medicine and healthcare away from ‘sick care’ toward comprehensive and disease-preventative healthspan extension. We are proud to have Jim as a Trustee of the Biogerontology Research Foundation and look forward to helping him lend mainstream credibility to the field and actionability to the dawning longevity industry” said Franco Cortese, Deputy Director & Trustee of the Biogerontology Research Foundation.

In 2012, Jim published his best-seller Cracking the Code, which summarized his vision for the future of the life science sector. In 2017, he announced his intention to focus much of his time and assets on the emerging longevity industry and make substantial investments into this area.

Jim and long-time co-author Al Chalabi toured many academic institutions, biopharmaceutical companies, and Silicon Valley tech companies to learn about the latest research and to understand the rapidly advancing field of longevity. Juvenescence highlights the technologies they deem the most likely to generate substantial longevity dividends and create sustainable and profitable industries. They travelled through the US and Europe, interviewing geroscience’s leading scientists and thought-leaders and provide an objective survey of their findings well as a detailed vision for the industry’s future and the most appropriate investment opportunities within the dawning longevity industry.

 

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Earlier this year Jim Mellon announced the formation of Juvenescence Limited, a company investing in the longevity biotechnology. Since then the company announced investments in several high-profile longevity companies including Insilico Medicine, Inc, a Baltimore-based leader in artificial intelligence for drug discovery, biomarker development, and aging research.

About the Biogerontology Research Foundation:

The Biogerontology Research Foundation is a UK non-profit research foundation and public policy center seeking to fill a gap within the research community, whereby the current scientific understanding of the ageing process is not yet being sufficiently exploited to produce effective medical interventions. The BGRF funds and conducts research which, building on the body of knowledge about how ageing happens, aims to develop biotechnological interventions to remediate the molecular and cellular deficits which accumulate with age and which underlie the ill-health of old age. Addressing ageing damage at this most fundamental level will provide an important opportunity to produce the effective, lasting treatments for the diseases and disabilities of ageing, required to improve quality of life in the elderly. The BGRF seeks to use the entire scope of modern biotechnology to attack the changes that take place in the course of ageing, and to address not just the symptoms of age-related diseases but also the mechanisms of those diseases.

Transhumanism: Contemporary Issues – Presentation by Gennady Stolyarov II at VSIM:17 Conference in Ravda, Bulgaria

Transhumanism: Contemporary Issues – Presentation by Gennady Stolyarov II at VSIM:17 Conference in Ravda, Bulgaria

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Gennady Stolyarov II


Gennady Stolyarov II, Chairman of the U.S. Transhumanist Party, outlines common differences in perspectives in three key areas of contemporary transhumanist discourse: artificial intelligence, religion, and privacy. Mr. Stolyarov follows his presentation of each issue with the U.S. Transhumanist Party’s official stances, which endeavor to resolve commonplace debates and find new common ground in these areas. Watch the video of Mr. Stolyarov’s presentation here.

This presentation was delivered by Mr. Stolyarov on September 14, 2017, virtually to the Vanguard Scientific Instruments in Management 2017 (VSIM:17) Conference in Ravda, Bulgaria. Mr. Stolyarov was introduced by Professor Angel Marchev, Sr. –  the organizer of the conference and the U.S. Transhumanist Party’s Ambassador to Bulgaria.

After his presentation, Mr. Stolyarov answered questions from the audience on the subjects of the political orientation of transhumanism, what the institutional norms of a transhuman society would look like, and how best to advance transhumanist ideas.

Download and view the slides of Mr. Stolyarov’s presentation (with hyperlinks) here.

Listen to the Transhumanist March (March #12, Op. 78), composed by Mr. Stolyarov in 2014, here.

Become a member of the U.S. Transhumanist Party for free, no matter where you reside. Fill out our Membership Application Form here.

Become a Foreign Ambassador for the U.S. Transhumanist Party. Apply here.

U.S. Transhumanist Party Discussion on Prosthetics, Neuroscience, and the Future of Human Potential

U.S. Transhumanist Party Discussion on Prosthetics, Neuroscience, and the Future of Human Potential

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Gennady Stolyarov II

Bobby Ridge

Scott Jurgens


U.S. Transhumanist Party Chairman Gennady Stolyarov II speaks with Secretary-Treasurer Bobby Ridge and Director of Applied Innovation Scott Jurgens regarding their areas of interest in research and study. Topics addressed include emerging advances in prosthetics, orthotics, 3D printing, 3D scanning, the science behind neuroplasticity, brain-computer interfaces (BCIs), artificial intelligence, and the societal implications of these technologies – including the extent to which they, combined with a universal basic income, may facilitate increased self-actualization by more people.

Conversations such as this one are prime examples of why the U.S. Transhumanist Party and the transhumanist movement are positioned to be the vanguard of the next era of our civilization, ready to rebuild it and take it to new heights, given sufficient recognition from and collaboration with the general public.

References

– Hugh Herr – “The new bionics that let us run, climb, and dance” – TED – March 2014
LimbForge – Enable Community Foundation
Autodesk Fusion 360
Thingiverse
– “Metal Gear Solid 5 Inspires an Amazing Prosthetic Arm” – Kendall Ashley – Nerdist – May 23, 2016

Become a member of the U.S. Transhumanist Party for free, no matter where you reside. Fill out our Membership Application Form here.

Become a Foreign Ambassador for the U.S. Transhumanist Party. Apply here.

A Future History of Mankind: Speculations of a Clever Ape – Article by Michael Hanson

A Future History of Mankind: Speculations of a Clever Ape – Article by Michael Hanson

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Michael Hanson


Long ago and very, VERY far away, the universe that we find ourselves in today was born. For billions of years, the universe has been completely inhospitable to life as we understand it. This remains the case today throughout much of the known universe, including right here in what we have come to believe is a “safe haven” for us.

Yes, the Earth that gave birth to us appears to be safe – for now. It is clearly much more hospitable to life than even the space just beyond our atmosphere. Make no mistake, however – danger lurks at every corner. Gamma rays from exploding stars millions of light years away; massive solar flares from our own beloved star; planet-obliterating asteroids; sociopathic world leaders armed to the teeth with megaton warheads; and superintelligent robots gone mad are just a few potential threats to the survival of life on this tiny speck of nothing floating in a vast ocean of cold indifference.

Have no fear, though. One of these things is not like the others. It could be the reverse of what we imagine it to be; it very well could be our saving grace.

“Superintelligence.” A term coined to describe the future of man-made technology. It is essentially the natural outcome of the very thing that makes us human: our deep-seated need to understand and master our surroundings. For millions of years now, mankind has made a somewhat steady march towards this goal.

We now stand on the brink of The Singularity – the point in spacetime where humans will be able to integrate the culmination of their millions-of-years-long pursuit of knowledge directly into their physiology. The benefits of this unspeakably beautiful possibility are immeasurable, and yet most of us fear it as much as – or more than – any other event imaginable.

Whether we fear it or not, The Singularity is inevitable. We would not be humans if we collectively decided to stop understanding and mastering our surroundings. If we somehow manage to dodge all of the other doomsday scenarios, we WILL see The Singularity come to fruition.

While it is extremely difficult to speculate what life will be like post-Singularity, it seems silly to think that life will remain as it is now. When every snot-nosed toddler has direct access to computational power exponentially greater than Albert Einstein could have ever hoped to have, diseases – including old age – will be a morbid footnote in the annals of spacetime. When the Neil deGrasse Tysons and Elon Musks of the world have instantaneous access to the accumulated knowledge of the last few hundred years, and the ability to research and master any subject in milliseconds, we will have very few problems.

It is likely that, with our new capabilities, humans will cease to be what we think of as humans altogether. We will be transhumans, a forced step forward in the evolutionary process. Once we transcend evolution, we transcend nature. In essence, we become “supernatural beings” – gods in our own right.

Where does this path lead us, and what does it mean for the “inhospitable” universe out there? Will we conquer “the final frontier” with our god-like powers? This also seems inevitable.

Imagine if we had the ability to “upload” our consciousnesses onto tiny, nearly weightless microchips. The problem of escaping this doomed planet seems ridiculously simple at that point. With no bodies requiring nourishment, being subject to radiation poisoning, or even weighing a spaceship down, it would be extraordinarily easy to transport thousands of sentient beings across vast expanses of spacetime in a vessel no larger than a modern automobile. With no threat of death due to the passage of time, the only real threat at that point is collision with comets and the like.

What would our problems be without any real threat of death? The scarcity of energy comes to mind. Without energy, everything dies. In space, the temperature is near Absolute Zero. This means that energy is NOT abundant, at least not in any form that we’re used to utilizing.

In fact, there is a finite amount of useable energy in the universe. It seems inevitable that our next great mission after The Singularity is to find useable energy throughout the universe and maximize its utility. We will view the destruction of useable energy as the greatest waste imaginable, similar to how we view the wasting of time now. Alas, before The Singularity, we are forced to view time as the most precious resource because we are tragically bound to expiration dates. When time is no longer a hindrance, energy will become vastly more precious.

What then, would be our likely solution to the need to collect and conserve as much energy as possible? Visions of stars wrapped in energy nets, and entire planets converted into generators dance in the head. Eventually, we may even convert entire solar systems, then galaxies, into energy farms to feed our superintelligent descendants. With the conversion of the energy of entire galaxies into fuel for self-evolving gods, all connected through an intergalactic internet which obliterates our notion of a separate “self,” it would not be long before the entire universe is made up of a single, omnipotent, omnipresent being.

It is possible that the end result of the universe is what we call “God.” This is the transposition of the Alpha and the Omega. It is possible that, rather than the universe being created by a supreme being, the opposite is true: the universe could be the womb wherein a supreme being is gestating.

In the end, it seems silly to worry about the “consequences” of our technological advances. Either way, we are destined for eradication in our present form. Whether by our own doing, or simply because the universe is indifferent to our desire to survive, the human race will eventually come to an end. Why not utilize the very essence of our species to escape this fate? What have we really got to lose in the end?

And they all lived happily ever after…

Michael Hanson founded the Transhumanist Research and Support Foundation and endeavors to assist the Transhumanist Party’s efforts in New Hampshire. 

Copyright 2017 Live and Live Free Media, LLC

Biogerontology Research Foundation Launches Campaign for Photographic Biomarkers of Age

Biogerontology Research Foundation Launches Campaign for Photographic Biomarkers of Age

Biogerontology Research Foundation


Thursday, August 31st, 2017, London, UK: The Biogerontology Research Foundation announces the launch of a crowdfunding campaign, MouseAge, to develop and test photographic biomarkers of ageing in mice in collaboration with scientists from Harvard University, University of Oxford, Youth Laboratories and Insilico Medicine. The project’s aim is to develop novel biomarkers of ageing in mice for the purposes of testing the effect of healthspan and lifespan-extending interventions. The project is now live at Lifespan.io, a crowdfunding platform for ageing research institutions that has launched several successful campaigns for SENS Research Foundation, International Longevity Alliance and CellAge.

“One of the most fundamental challenges in ageing research today is the development of robust and reliable biomarkers of ageing to serve as the basis by which the efficacy of lifespan and healthspan-extending interventions can be tested. Humans live a long time, and testing the effect of geroprotective interventions in humans using lifespan gains as the main criterion for success would be wildly impractical, necessitating long and costly longitudinal studies. By developing accurate biomarkers of ageing, the efficacy of potential geroprotective interventions could instead be tested according to changes in study participants’ biomarkers of ageing. While significant attention is paid to the development of highly accurate biomarkers of ageing, less attention is paid to developing actionable biomarkers of ageing that can be tested inexpensively using the tools at hand to the majority of researchers and clinicians. The Biogerontology Research Foundation chose to support MouseAge.org because photographic biomarkers of ageing represents a highly actionable alternative to more expensive measures of biological age.” said Franco Cortese, Deputy Director & Trustee of the Biogerongology Research Foundation.

The project utilizes Insilico Medicine’s novel deep learning platforms to correlate changes in physical appearance with biological and chronological age. Insilico is leading the pack in the intersection of deep learning and ageing research, and is well known for its use of advances in genomics, big data analysis, and deep learning for in silico drug discovery and drug repurposing for ageing and age-related diseases. The Biogerontology Research Foundation has collaborated with Insilico Medicine in the development of actionable and practical biomarkers of ageing before through their Ageing.AI project, and both organizations hope that MouseAge is the next in a long line of continuing research into the development of actionable biomarkers of ageing via the intersection of longevity research and deep learning.

“There are many experiments conducted around the world that examine lifespan in mice. The artificially intelligent MouseAge system will help determine which interventions make mice look younger. The plan is to develop an accurate predictor of mouse biological age based on images of mice and then apply transfer learning techniques to other datasets and data types,” said Vadim Gladyshev, MouseAge Research Lead and Professor of Medicine at Brigham and Women’s Hospital, Harvard Medical School.

Milestones for the project include the design of standardized protocols for creating photos and videos of mice, developing a mobile app and server infrastructure for image data collection, developing and testing the project’s main algorithm for mouse age prediction, optimizing feature extraction to investigate visual biomarkers of ageing in mice, creating a central data repository for the project’s data, utilizing transfer learning techniques to make these methods applicable to other model organisms, and ultimately using transfer learning techniques to develop photographic biomarkers of ageing in humans. The project’s principal investigator is Anastasia Georgievskaya, co-founder of Youth Laboratories, a company working at the intersection of ageing research, AI and machine vision, with the ultimate goal of using facial imageing data to predict patient health status.

The ultimate end-goal of MouseAge is to develop an intuitive mobile app to be used by researchers across the globe free of charge, where users can take images of model organisms and have the project’s DP-based algorithms perform age-assessment of images uploaded by users of the app. Both the organizations and researchers behind MouseAge are united in their belief in the promise of AI to accelerate ageing research and to streamline the development of effective healthspan-extending interventions for use in human patients, and hope that MouseAge comes to be remembered as an important landmark in the ongoing paradigm shift away from costly and inefficient sick-care and toward morbidity compression and effective healthspan extension for the benefit of all.

“Ageing research is the most altruistic cause that can generate billions of quality-adjusted life years over time and save the global economy. We are very happy to contribute to and support the MouseAge project. Our Young.AI system for tracking multiple biomarkers during human ageing is currently in the alpha stage and is launching in the fall. However, the biological relevance of many of the biomarkers and interventions is yet to be established, and the MouseAge project contributes to the body of fundamental science required to bridge AI and longevity research. Please support the MouseAge project on LifeSpan.io to contribute to this grand effort”, said Alex Zhavoronkov, PhD, Chief Science Officer of the Biogerontology Research Foundation.

About the Biogerontology Research Foundation:

The Biogerontology Research Foundation is a UK non-profit research foundation and public policy center seeking to fill a gap within the research community, whereby the current scientific understanding of the ageing process is not yet being sufficiently exploited to produce effective medical interventions. The BGRF funds and conducts research which, building on the body of knowledge about how ageing happens, aims to develop biotechnological interventions to remediate the molecular and cellular deficits which accumulate with age and which underlie the ill-health of old age. Addressing ageing damage at this most fundamental level will provide an important opportunity to produce the effective, lasting treatments for the diseases and disabilities of ageing, required to improve quality of life in the elderly. The BGRF seeks to use the entire scope of modern biotechnology to attack the changes that take place in the course of ageing, and to address not just the symptoms of age-related diseases but also the mechanisms of those diseases.

Panel – Artificial Intelligence & Robots: Economy of the Future or End of Free Markets? – Michael Shermer, Edward Hudgins, Zoltan Istvan, Gennady Stolyarov II, Eric Shuss

Panel – Artificial Intelligence & Robots: Economy of the Future or End of Free Markets? – Michael Shermer, Edward Hudgins, Zoltan Istvan, Gennady Stolyarov II, Eric Shuss

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Gennady Stolyarov II


Gennady Stolyarov II, Chairman of the U.S. Transhumanist Party, participated in the panel discussion at FreedomFest in Las Vegas on July 21, 2017, entitled “AI & Robots: Economy of the Future or End of Free Markets?” The panelists presented a set of realistic, balanced analyses on the impact of artificial intelligence and automation.

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For this event there was an outstanding speaker lineup, with moderator Michael Shermer, followed by Edward Hudgins, Peter Voss, Zoltan Istvan, Gennady Stolyarov II, and Eric Shuss.

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The general focus of Mr. Stolyarov’s remarks was to dispel AI-oriented doomsaying and convey the likely survival of the capitalist economy for at least the forthcoming several decades – since narrow AI cannot automate away jobs requiring creative human judgment.

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The video was recorded by filmmaker Ford Fischer and is reproduced with his permission.

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