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“Squeak” – Art by Laura Katrin Weston, a.k.a. Katrin Brunier

“Squeak” – Art by Laura Katrin Weston, a.k.a. Katrin Brunier

Laura Katrin Weston

Commentary by Gennady Stolyarov II, Chairman, United States Transhumanist Party: “Squeak” is a print by Dr. Laura Katrin Weston, a.k.a. Katrin Brunier, the original exemplar of which I received in November 2017 due to my donation to the successful MouseAge crowdfunding campaign by

It is fitting for a project on mouse longevity to involve at least one image of mice – creatures whom life has unfortunately dealt a bad hand, due to their short lifespans (only 3 years for even long-lived mice in the absence of medical intervention), difficulty in getting along with humans, and unnecessary attrition due to disposal practices after lab experiments. “Squeak” invites the viewer to appreciate mice a bit more; if we can extend their lives significantly, we stand a decent chance of achieving dramatic extension of our own lifespans.  Perhaps we can also give some of the mice a break by using photographic markers of aging in experiments, as the MouseAge project seeks to do.

Here, the mice are depicted scurrying along a narrow circular path. The golden circle, with rays emanating outward represents perhaps the great hope that these creatures unknowingly provide to us. One may wonder, as I have done over many months of reflecting on this work, whether these are mutant, two-tailed mice, or whether they each just have their ordinary curly tails, and the track along which they move might simply be painted in the same colors and textures as their tails. (Well, in actuality it is indeed painted that way!) Mutant or not, these mice are rather extraordinary in having become emblems of a species that has added much to our understanding. Unlike most of their brethren to date, these mice have earned their extreme longevity through Laura Katrin Weston’s brush.

You can find more work by Dr. Laura Katrin Weston at the Katrin Brunier Gallery, an Ethical Investment-Grade Art Gallery for the Neo-Renaissance Era (see its Instagram page). Proceeds from art sales at the Katrin Brunier Gallery will go to support causes such as medical research and conservation.

Being Excited About Failure – Article by Martin van der Kroon

Being Excited About Failure – Article by Martin van der Kroon

Martin van der Kroon

The much hyped CRISPR-Cas9 genome-editing technique often explained as being the ‘DNA scissors’ or the ‘cut and paste’ technique, has had a setback, and this has me excited.

CRISPR-Cas9 has has the scientific community, and in particular those involved in research and development of genome editing, raving over the roughly past 3 years. It is hailed as a cheap and fast way to edit genomes with great accuracy compared to other genome-editing techniques, and this is true. Now however, researchers have found CRISPR-Cas9 to have some annoying side-effects. The side-effects were found in mice who had their blindness corrected but also caused mutations in other parts of the DNA sequence, roughly 1500 mutations. It is unknown what the consequences of the mutations are at this moment.

“Why am I excited about this setback?” you might ask.

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