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Jim Mellon Announces Launch of New Book – Juvenescence: Investing in the Age of Longevity – Press Release by Biogerontology Research Foundation

Jim Mellon Announces Launch of New Book – Juvenescence: Investing in the Age of Longevity – Press Release by Biogerontology Research Foundation

Biogerontology Research Foundation


London, UK: Biogerontology Research Foundation Trustee Jim Mellon announces the publication of his newest book, Juvenescence: Investing in the Age of Longevity.

The book is a comprehensive summary of the emerging longevity industry, including profiles of longevity companies, investment opportunities, and aims to chart the major ideas of the geroscience’s thought-leaders and the vast implications this will have on economies and societies.

Often referred to as the British Warren Buffett, Billionaire Jim Mellon is well known for identifying major emerging trends before they become mainstream. Mellon made his wealth by investing in emerging markets throughout the 1990s. After many years of research and investing in the life science sector, Jim announced his vision for the emergence of the nascent longevity industry at Master Investor, one of the UK’s leading investor show in March of 2017, which was attended by over five thousand investors and entrepreneurs.

“The Biogerontology Research Foundation is proud to support what we feel will come to be seen as a landmark publication in the modern history of biogerontology. Jim has put an enormous amount of thought and effort into this new book, and has interviewed many of the field’s leading scientists in his research. The field of geroscience and the emerging longevity industry are both sure to prosper from very well-respected business personalities like Jim Mellon championing the longevity industry and projecting that it will become the world’s largest industry. Further, governments and policy makers should note the pressing need for a paradigm shift in medicine and healthcare away from ‘sick care’ toward comprehensive and disease-preventative healthspan extension. We are proud to have Jim as a Trustee of the Biogerontology Research Foundation and look forward to helping him lend mainstream credibility to the field and actionability to the dawning longevity industry” said Franco Cortese, Deputy Director & Trustee of the Biogerontology Research Foundation.

In 2012, Jim published his best-seller Cracking the Code, which summarized his vision for the future of the life science sector. In 2017, he announced his intention to focus much of his time and assets on the emerging longevity industry and make substantial investments into this area.

Jim and long-time co-author Al Chalabi toured many academic institutions, biopharmaceutical companies, and Silicon Valley tech companies to learn about the latest research and to understand the rapidly advancing field of longevity. Juvenescence highlights the technologies they deem the most likely to generate substantial longevity dividends and create sustainable and profitable industries. They travelled through the US and Europe, interviewing geroscience’s leading scientists and thought-leaders and provide an objective survey of their findings well as a detailed vision for the industry’s future and the most appropriate investment opportunities within the dawning longevity industry.

 

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Earlier this year Jim Mellon announced the formation of Juvenescence Limited, a company investing in the longevity biotechnology. Since then the company announced investments in several high-profile longevity companies including Insilico Medicine, Inc, a Baltimore-based leader in artificial intelligence for drug discovery, biomarker development, and aging research.

About the Biogerontology Research Foundation:

The Biogerontology Research Foundation is a UK non-profit research foundation and public policy center seeking to fill a gap within the research community, whereby the current scientific understanding of the ageing process is not yet being sufficiently exploited to produce effective medical interventions. The BGRF funds and conducts research which, building on the body of knowledge about how ageing happens, aims to develop biotechnological interventions to remediate the molecular and cellular deficits which accumulate with age and which underlie the ill-health of old age. Addressing ageing damage at this most fundamental level will provide an important opportunity to produce the effective, lasting treatments for the diseases and disabilities of ageing, required to improve quality of life in the elderly. The BGRF seeks to use the entire scope of modern biotechnology to attack the changes that take place in the course of ageing, and to address not just the symptoms of age-related diseases but also the mechanisms of those diseases.

Our Moral Obligation to Cure Aging – Aubrey de Grey Interviewed by Why? Radio

Our Moral Obligation to Cure Aging – Aubrey de Grey Interviewed by Why? Radio

Dr. Aubrey de Grey

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Dr. Aubrey de Grey in this interview explains and advocates for curing of aging, i.e., rejuvenation of the old to become youthful; preventing the youth from being old biologically, and other related points.

Aubrey de Grey is the U.S. Transhumanist Party’s Anti-Aging Advisor. He is a biomedical gerontologist based in Cambridge, UK and Mountain View, California, USA, and is the Chief Science Officer of SENS Research Foundation, a California-based 501(c)(3) charity dedicated to combating the aging process. He is also Editor-in-Chief of Rejuvenation Research, the world’s highest-impact peer-reviewed journal focused on intervention in aging.

This interview was conducted by Why? Radio, a program of the Institute for Philosophy in Public Life. You can also find it here.

 

 

 

I am the Lifespan – Video by Gennady Stolyarov II

I am the Lifespan – Video by Gennady Stolyarov II

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Gennady Stolyarov II


Gennady Stolyarov II, Chairman of the United States Transhumanist Party, discusses why longevity research is crucial, and how our generation stands on the threshold of finally dealing a decisive blow to the age-old enemies of aging and death, which have destroyed great human minds since the emergence of our species.

This video is part of the #IAmTheLifespan campaign, coordinated by Lifespan.io and the Life Extension Advocacy Foundation (LEAF) for Longevity Month, October 2017. Read more about this campaign here.

Become a member of the U.S. Transhumanist Party for free, no matter where you reside. Fill out our Membership Application Form here.

Become a Foreign Ambassador for the U.S. Transhumanist Party. Apply here.

The U.S. Transhumanist Party – Pursuing a Peaceful Political Revolution for Longevity – RAAD Fest 2017 Presentation by Gennady Stolyarov II

The U.S. Transhumanist Party – Pursuing a Peaceful Political Revolution for Longevity – RAAD Fest 2017 Presentation by Gennady Stolyarov II

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Gennady Stolyarov II


Gennady Stolyarov II, Chairman of the United States Transhumanist Party, delivered this presentation as the initial speech in the panel discussion he moderated at RAAD Fest 2017, entitled “Advocating for the Future”. The audience consisted of approximately 700 in-person attendees.

Other speakers in the panel included Zoltan Istvan, Ben Goertzel, Max More, and Natasha Vita-More.

Gennady Stolyarov II Prepares to Present and Moderate Panel at RAAD Fest 2017

Gennady Stolyarov II Presents at RAAD Fest 2017

Gennady Stolyarov II Moderates Question-and-Answer Session for Panel: “Advocating for the Future” – RAAD Fest 2017

From left to right, Zoltan Istvan, Gennady Stolyarov II, Max More, Ben Goertzel, and Natasha Vita-More

Become a member of the U.S. Transhumanist Party for free, no matter where you reside. Fill out our Membership Application Form here.

Become a Foreign Ambassador for the U.S. Transhumanist Party. Fill out our Application Form here.

Biogerontology Research Foundation Launches Campaign for Photographic Biomarkers of Age

Biogerontology Research Foundation Launches Campaign for Photographic Biomarkers of Age

Biogerontology Research Foundation


Thursday, August 31st, 2017, London, UK: The Biogerontology Research Foundation announces the launch of a crowdfunding campaign, MouseAge, to develop and test photographic biomarkers of ageing in mice in collaboration with scientists from Harvard University, University of Oxford, Youth Laboratories and Insilico Medicine. The project’s aim is to develop novel biomarkers of ageing in mice for the purposes of testing the effect of healthspan and lifespan-extending interventions. The project is now live at Lifespan.io, a crowdfunding platform for ageing research institutions that has launched several successful campaigns for SENS Research Foundation, International Longevity Alliance and CellAge.

“One of the most fundamental challenges in ageing research today is the development of robust and reliable biomarkers of ageing to serve as the basis by which the efficacy of lifespan and healthspan-extending interventions can be tested. Humans live a long time, and testing the effect of geroprotective interventions in humans using lifespan gains as the main criterion for success would be wildly impractical, necessitating long and costly longitudinal studies. By developing accurate biomarkers of ageing, the efficacy of potential geroprotective interventions could instead be tested according to changes in study participants’ biomarkers of ageing. While significant attention is paid to the development of highly accurate biomarkers of ageing, less attention is paid to developing actionable biomarkers of ageing that can be tested inexpensively using the tools at hand to the majority of researchers and clinicians. The Biogerontology Research Foundation chose to support MouseAge.org because photographic biomarkers of ageing represents a highly actionable alternative to more expensive measures of biological age.” said Franco Cortese, Deputy Director & Trustee of the Biogerongology Research Foundation.

The project utilizes Insilico Medicine’s novel deep learning platforms to correlate changes in physical appearance with biological and chronological age. Insilico is leading the pack in the intersection of deep learning and ageing research, and is well known for its use of advances in genomics, big data analysis, and deep learning for in silico drug discovery and drug repurposing for ageing and age-related diseases. The Biogerontology Research Foundation has collaborated with Insilico Medicine in the development of actionable and practical biomarkers of ageing before through their Ageing.AI project, and both organizations hope that MouseAge is the next in a long line of continuing research into the development of actionable biomarkers of ageing via the intersection of longevity research and deep learning.

“There are many experiments conducted around the world that examine lifespan in mice. The artificially intelligent MouseAge system will help determine which interventions make mice look younger. The plan is to develop an accurate predictor of mouse biological age based on images of mice and then apply transfer learning techniques to other datasets and data types,” said Vadim Gladyshev, MouseAge Research Lead and Professor of Medicine at Brigham and Women’s Hospital, Harvard Medical School.

Milestones for the project include the design of standardized protocols for creating photos and videos of mice, developing a mobile app and server infrastructure for image data collection, developing and testing the project’s main algorithm for mouse age prediction, optimizing feature extraction to investigate visual biomarkers of ageing in mice, creating a central data repository for the project’s data, utilizing transfer learning techniques to make these methods applicable to other model organisms, and ultimately using transfer learning techniques to develop photographic biomarkers of ageing in humans. The project’s principal investigator is Anastasia Georgievskaya, co-founder of Youth Laboratories, a company working at the intersection of ageing research, AI and machine vision, with the ultimate goal of using facial imageing data to predict patient health status.

The ultimate end-goal of MouseAge is to develop an intuitive mobile app to be used by researchers across the globe free of charge, where users can take images of model organisms and have the project’s DP-based algorithms perform age-assessment of images uploaded by users of the app. Both the organizations and researchers behind MouseAge are united in their belief in the promise of AI to accelerate ageing research and to streamline the development of effective healthspan-extending interventions for use in human patients, and hope that MouseAge comes to be remembered as an important landmark in the ongoing paradigm shift away from costly and inefficient sick-care and toward morbidity compression and effective healthspan extension for the benefit of all.

“Ageing research is the most altruistic cause that can generate billions of quality-adjusted life years over time and save the global economy. We are very happy to contribute to and support the MouseAge project. Our Young.AI system for tracking multiple biomarkers during human ageing is currently in the alpha stage and is launching in the fall. However, the biological relevance of many of the biomarkers and interventions is yet to be established, and the MouseAge project contributes to the body of fundamental science required to bridge AI and longevity research. Please support the MouseAge project on LifeSpan.io to contribute to this grand effort”, said Alex Zhavoronkov, PhD, Chief Science Officer of the Biogerontology Research Foundation.

About the Biogerontology Research Foundation:

The Biogerontology Research Foundation is a UK non-profit research foundation and public policy center seeking to fill a gap within the research community, whereby the current scientific understanding of the ageing process is not yet being sufficiently exploited to produce effective medical interventions. The BGRF funds and conducts research which, building on the body of knowledge about how ageing happens, aims to develop biotechnological interventions to remediate the molecular and cellular deficits which accumulate with age and which underlie the ill-health of old age. Addressing ageing damage at this most fundamental level will provide an important opportunity to produce the effective, lasting treatments for the diseases and disabilities of ageing, required to improve quality of life in the elderly. The BGRF seeks to use the entire scope of modern biotechnology to attack the changes that take place in the course of ageing, and to address not just the symptoms of age-related diseases but also the mechanisms of those diseases.

MouseAge: Using Artificial Intelligence to Determine Age and Assess Therapies Against Aging – Project by Lifespan.io

MouseAge: Using Artificial Intelligence to Determine Age and Assess Therapies Against Aging – Project by Lifespan.io

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United States Transhumanist Party


According to Article 3, Section V of the Constitution of the United States Transhumanist Party:

“The United States Transhumanist Party supports concerted research in effort to eradicate disease and illness that wreak havoc upon and cause death of sapient beings. We strongly advocate the increase and redirection of research funds to conduct research and experiments and to explore life, science, technology, medicine, and extraterrestrial realms to improve all sentient entities.”

Which is why the U.S. Transhumanist Party is pleased to announce the official launch of the fundraising campaign for the MouseAge project. MouseAge is a longevity-based project started by one of our Allied Organizations, Lifespan.io, of which we’ll provide relevant information below:

Read More Read More

LEAF Panel: How to Promote Longevity? ft. Drs. Aubrey de Grey, Alexandra Stolzing, Oliver Medvedik

LEAF Panel: How to Promote Longevity? ft. Drs. Aubrey de Grey, Alexandra Stolzing, Oliver Medvedik

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Keith Comito
Oliver Medvedik
Steve Hill
Elena Milova
Aubrey de Grey
Alexandra Stolzing
Alen Akhabaev


The U.S. Transhumanist Party is pleased to feature this extensive discussion, hosted by our allies at LEAF – the Life Extension Advocacy Foundation.

Description by LEAF: Dr. Alexandra Stolzing, Dr. Aubrey de Grey, Dr. Oliver Medvedik and a number of other guests discuss longevity, advocacy and rejuvenation biotechnology in an exclusive panel hosted by the Life Extension Advocacy Foundation (LEAF). This panel, moderated by LEAF president Keith Comito, talks about the latest progress in rejuvenation biotechnology and about how to engage, educate and excite the public regarding cutting-edge medicine.

Panel: Dr. Alexandra Stolzing, Dr. Aubrey de Grey, Dr. Oliver Medvedik , Elena Milova, Keith Comito, Steve Hill and Alen Akhabaev.

Subscribe to LEAF’s video channel for more.

Support LEAF’s work by becoming a “Lifespan Hero”: http://lifespan.io/hero

The Great Transhumanist Game – How to Win; How to Play and Not to Play – Videos by Gennady Stolyarov II

The Great Transhumanist Game – How to Win; How to Play and Not to Play – Videos by Gennady Stolyarov II

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Gennady Stolyarov II


This two-part video series was created by Gennady Stolyarov II, Chairman of the U.S. Transhumanist Party, to serve as pieces in the Great Transhumanist Game orchestrated by Professor Angel Marchev, Sr., Ph.D., of the University of National and World Economy in Sofia, Bulgaria.

The Great Transhumanist Game – Part 1 – How to Win

What would it mean to win in the Great Transhumanist Game? Mr. Stolyarov answers that winning would be inaugurating the next great era of human civilization, and living to see it.

The Great Transhumanist Game – Part 2 – How to Play and Not to Play

Now that we know what it would mean to win the Great Transhumanist Game, how do we get from here to there? Mr. Stolyarov discusses the importance of knowing which game one is playing, and whose, and abstaining from playing the wrong, counterproductive political or insurrectionary games.

Become a member of the U.S. Transhumanist Party for free, no matter where you reside. Fill out our Membership Application Form here.

Become a Foreign Ambassador for the U.S. Transhumanist Party. Fill out our Application Form here.

U.S. Transhumanist Party Q&A Session – July 15, 2017

U.S. Transhumanist Party Q&A Session – July 15, 2017

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Gennady Stolyarov II
B.J. Murphy
Bobby Ridge
Scott Jurgens
Martin van der Kroon


In this interactive question-and-answer session, scheduled for 11 a.m. U.S. Pacific Time on Saturday, July 15, 2017, U.S. Transhumanist Party Officers answered members’ and the public’s questions about the ongoing activities and objectives of the United States Transhumanist Party and also discussed other issues of interest that relate to emerging technologies and how to ensure the best possible future for sentient entities.

The following Officers were present for this Q&A session:

Gennady Stolyarov II, Chairman
B.J. Murphy, Director of Social Media
Martin van der Kroon, Director of Recruitment
Bobby Ridge, Secretary-Treasurer
Scott Jurgens, Director of Applied Innovation

Because of an unexpected technical difficulty, the video stream was split into two portions.

Watch Part 1 here.

Watch Part 2 here.

Join the U.S. Transhumanist Party for free by filling out our membership application form at https://goo.gl/forms/IpUjooEZjnfOFUMi2.

Visit the U.S. Transhumanist Party Facebook page at https://www.facebook.com/USTranshumanistParty/.

Visit the U.S. Transhumanist Party Twitter page at https://twitter.com/USTranshumanist.

City of New Antideath – Painting by Ekaterinya Vladinakova, Commissioned by Gennady Stolyarov II

City of New Antideath – Painting by Ekaterinya Vladinakova, Commissioned by Gennady Stolyarov II

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Art by Ekaterinya Vladinakova

Painting Commissioned by Gennady Stolyarov II


City of New AntideathCity of New Antideath – Painting by Ekaterinya Vladinakova

Commentary by Gennady Stolyarov II, Chairman of the United States Transhumanist Party, Editor-in-Chief of The Rational Argumentator

For my coming thirtieth birthday, I have commissioned a colossal cityscape depicting my vision and hope for the future progress of humankind. Artist Ekaterinya Vladinakova, a long-time supporter of transhumanism and life extension, was the evident best choice for this project.

The City of New Antideath represents a future society which has overcome death, disease, and today’s principal sources of material scarcity and discomfort. This city contains more than ample living space in ornate, radiantly illuminated skyscrapers. Smaller villas, domed towers, and other luxuriously ornamented buildings adorn the central walkways. There is ample room for pedestrian traffic and plant growth sculpted into geometrically complex patterns – including on the rooftop terraces of many of the mega-skyscrapers.

Flying cars and autonomous drones appear as streaks of light from the ground level. There is so much room for aerial transportation that no more traffic jams exist on the ground. One can opt for efficient transport, or for open-ended leisurely walking, and the two modes will not collide.

Over the years I have created a large number of building models using Sketchup, Minecraft, and even LEGO bricks. In my quest for permanence, they – or images of them – have been preserved and provided to the artist for inspiration. The first City of Antideath consisted of my Sketchup models. The City of New Antideath was not intended to be an exact replica, but rather a successor inspired by the prospect of juxtaposing the best architectural elements of all eras – past and yet to come.

I conveyed to Ekaterinya Vladinakova that the skyscrapers should exhibit a variety of bold colors and geometric shapes – but also be orderly and ornate. I have a great admiration for historical architecture from the 16th through 19th centuries – so while some of the buildings are geometric and futuristic, others borrow significant elements from Renaissance, Baroque, Neoclassical, or Victorian styles. Russian and Eastern architectural traditions find their manifestations in this cityscape as well. The idea is to portray a future of extreme diversity, where all of these elements will exist side by side and interact with one another in interesting ways. Far from cultural separatism or tribalism, the future needs to borrow and develop upon the best elements from all cultures, times, and places. The culture of New Antideath is rational, scientific, progress-oriented, universalist, cosmopolitan, and at the same time hyperpluralist and welcoming of all peaceful individuals.

The most significant vision I have for this artwork is that it will become the iconic vision of a techno-positive future. Accordingly, I am rendering it available for free download and distribution via a Creative Commons Attribution Share-Alike License so that it might be used by others who seek illustrations of a future we can all aspire for.

I still hope that I was not born too soon – that I may someday personally witness and experience a future of this sort. But for now, although the third decade of my life did not see such a future emerge, I am happy at least to have enabled its depiction so that others can be inspired to strive toward it. Given that our immediate world has become suffused by a pervasive, destructive malaise over the past two years, we will need visions such as this to overcome it and achieve better ways to be.

There are three versions of this digital painting available for free download (left-click on the links to open, right-click to download):

Small (1200 by 1931 pixels)

Medium (2400 by 3861 pixels)

Original Size (11250 by 18100 pixels – a vast canvas with immense detail. Note: This file size is immense as well – but you will be able to zoom in to view individual buildings and regard them as smaller-scale paintings in their own right.)

For those seeking musical accompaniment in viewing this painting, I recommend my Transhumanist March, Op. 78 (2014) (MP3 and YouTube)  or Man’s Struggle Against Death, Op. 58 (2008) (MP3 and YouTube).

Find out more about Mr. Stolyarov here.

Ekaterinya Vladinakova is an accomplished digital painter. See her gallery here and her DeviantArt page here.