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The Great Transhumanist Game – How to Win; How to Play and Not to Play – Videos by Gennady Stolyarov II

The Great Transhumanist Game – How to Win; How to Play and Not to Play – Videos by Gennady Stolyarov II

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Gennady Stolyarov II


This two-part video series was created by Gennady Stolyarov II, Chairman of the U.S. Transhumanist Party, to serve as pieces in the Great Transhumanist Game orchestrated by Professor Angel Marchev, Sr., Ph.D., of the University of National and World Economy in Sofia, Bulgaria.

The Great Transhumanist Game – Part 1 – How to Win

What would it mean to win in the Great Transhumanist Game? Mr. Stolyarov answers that winning would be inaugurating the next great era of human civilization, and living to see it.

The Great Transhumanist Game – Part 2 – How to Play and Not to Play

Now that we know what it would mean to win the Great Transhumanist Game, how do we get from here to there? Mr. Stolyarov discusses the importance of knowing which game one is playing, and whose, and abstaining from playing the wrong, counterproductive political or insurrectionary games.

Become a member of the U.S. Transhumanist Party for free, no matter where you reside. Fill out our Membership Application Form here.

Become a Foreign Ambassador for the U.S. Transhumanist Party. Fill out our Application Form here.

A “Disease” Approach in Life-Extension Advocacy Can Facilitate Communication with the General Public – Infographic by Elena Milova and Keith Comito

A “Disease” Approach in Life-Extension Advocacy Can Facilitate Communication with the General Public – Infographic by Elena Milova and Keith Comito

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Elena Milova and Keith Comito


The U.S. Transhumanist Party is pleased to share this infographic from our friends at the Life Extension Advocacy Foundation (LEAF), one of the Transhumanist Party’s most active Allied Organizations. Life-extension advocates Elena Milova and Keith Comito have compiled a set of tips for communicating ideas regarding the progress of medical science and technology, for the pursuit of healthy life extension, in such a manner as to enable many in the general public to understand and sympathize with our goals and the science behind them. We encourage you to distribute this infographic to any activists and advocates who you think would benefit from the advice therein.

U.S. Transhumanist Party Q&A Session – July 15, 2017

U.S. Transhumanist Party Q&A Session – July 15, 2017

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Gennady Stolyarov II
B.J. Murphy
Bobby Ridge
Scott Jurgens
Martin van der Kroon


In this interactive question-and-answer session, scheduled for 11 a.m. U.S. Pacific Time on Saturday, July 15, 2017, U.S. Transhumanist Party Officers answered members’ and the public’s questions about the ongoing activities and objectives of the United States Transhumanist Party and also discussed other issues of interest that relate to emerging technologies and how to ensure the best possible future for sentient entities.

The following Officers were present for this Q&A session:

Gennady Stolyarov II, Chairman
B.J. Murphy, Director of Social Media
Martin van der Kroon, Director of Recruitment
Bobby Ridge, Secretary-Treasurer
Scott Jurgens, Director of Applied Innovation

Because of an unexpected technical difficulty, the video stream was split into two portions.

Watch Part 1 here.

Watch Part 2 here.

Join the U.S. Transhumanist Party for free by filling out our membership application form at https://goo.gl/forms/IpUjooEZjnfOFUMi2.

Visit the U.S. Transhumanist Party Facebook page at https://www.facebook.com/USTranshumanistParty/.

Visit the U.S. Transhumanist Party Twitter page at https://twitter.com/USTranshumanist.

In Time For Everyone, A Reason To Support Us – Article by Martin van der Kroon

In Time For Everyone, A Reason To Support Us – Article by Martin van der Kroon

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Martin van der Kroon


There is a lot of inequality in the world, from economic or wealth inequality to inequality of opportunity, to inequality that may have to do with ethnicity, biological sex, or gender. It is not a surprise when I say that we can do without new inequalities. This is exactly what some critics of transhumanism fear, that with the coming possibility of indefinite life-extension we will face lifespan inequality.

I think they are justified in their fears. Let’s take a step back and illustrate what that would look like, as for many indefinite life extension seems like science fiction, and at the moment it still is. What would a world with lifespan inequality look like?

(Spoilers for the movie In Time (2011) ahead)

Although often compared to society’s current situation of wealth inequality, the movie In Time might actually be more directly linked to a fear of lifespan inequality, for the obvious reason that the movie is about humans being able to buy ‘life-time’, but also have to spend it.

As per the In Time movie’s IMDB page: “In a future where people stop aging at 25, but are engineered to live only one more year, having the means to buy your way out of the situation is a shot at immortal youth. …”

In the movie the wealthy accumulate time as a means of profit, and by extension extra life time. The less fortunate have their daily lives, but are always close to their time running out. Obviously the chances of this exact scenario are slim, but the metaphor is apt nonetheless. Wealth can buy almost anything, and in a future where indefinite life extension is possible, the wealthy will want to buy this, too.

The problem we face is whether we end up getting into a situation similar to the movie In Time, the wealthy having time, and the poor almost always out of time, or whether we can create a framework to make life extension available and accessible to everyone, rich, poor, and everything in between.

The science and willingness to make indefinite life-extension possible are fascinating and amazing, but the critics are right that we have to tread carefully in how it may be applied.

This is a reason why, even if you otherwise do not consider yourself a transhumanist, you might wish to consider supporting the U.S. Transhumanist Party. As a political party looking towards the future, we strive to create a framework that makes available and accessible to all the possibility of indefinite life extension so that we may prevent another inequality from entering our world.

Martin van der Kroon is the Director of Recruitment for the U.S. Transhumanist Party.

City of New Antideath – Painting by Ekaterinya Vladinakova, Commissioned by Gennady Stolyarov II

City of New Antideath – Painting by Ekaterinya Vladinakova, Commissioned by Gennady Stolyarov II

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Art by Ekaterinya Vladinakova

Painting Commissioned by Gennady Stolyarov II


City of New AntideathCity of New Antideath – Painting by Ekaterinya Vladinakova

Commentary by Gennady Stolyarov II, Chairman of the United States Transhumanist Party, Editor-in-Chief of The Rational Argumentator

For my coming thirtieth birthday, I have commissioned a colossal cityscape depicting my vision and hope for the future progress of humankind. Artist Ekaterinya Vladinakova, a long-time supporter of transhumanism and life extension, was the evident best choice for this project.

The City of New Antideath represents a future society which has overcome death, disease, and today’s principal sources of material scarcity and discomfort. This city contains more than ample living space in ornate, radiantly illuminated skyscrapers. Smaller villas, domed towers, and other luxuriously ornamented buildings adorn the central walkways. There is ample room for pedestrian traffic and plant growth sculpted into geometrically complex patterns – including on the rooftop terraces of many of the mega-skyscrapers.

Flying cars and autonomous drones appear as streaks of light from the ground level. There is so much room for aerial transportation that no more traffic jams exist on the ground. One can opt for efficient transport, or for open-ended leisurely walking, and the two modes will not collide.

Over the years I have created a large number of building models using Sketchup, Minecraft, and even LEGO bricks. In my quest for permanence, they – or images of them – have been preserved and provided to the artist for inspiration. The first City of Antideath consisted of my Sketchup models. The City of New Antideath was not intended to be an exact replica, but rather a successor inspired by the prospect of juxtaposing the best architectural elements of all eras – past and yet to come.

I conveyed to Ekaterinya Vladinakova that the skyscrapers should exhibit a variety of bold colors and geometric shapes – but also be orderly and ornate. I have a great admiration for historical architecture from the 16th through 19th centuries – so while some of the buildings are geometric and futuristic, others borrow significant elements from Renaissance, Baroque, Neoclassical, or Victorian styles. Russian and Eastern architectural traditions find their manifestations in this cityscape as well. The idea is to portray a future of extreme diversity, where all of these elements will exist side by side and interact with one another in interesting ways. Far from cultural separatism or tribalism, the future needs to borrow and develop upon the best elements from all cultures, times, and places. The culture of New Antideath is rational, scientific, progress-oriented, universalist, cosmopolitan, and at the same time hyperpluralist and welcoming of all peaceful individuals.

The most significant vision I have for this artwork is that it will become the iconic vision of a techno-positive future. Accordingly, I am rendering it available for free download and distribution via a Creative Commons Attribution Share-Alike License so that it might be used by others who seek illustrations of a future we can all aspire for.

I still hope that I was not born too soon – that I may someday personally witness and experience a future of this sort. But for now, although the third decade of my life did not see such a future emerge, I am happy at least to have enabled its depiction so that others can be inspired to strive toward it. Given that our immediate world has become suffused by a pervasive, destructive malaise over the past two years, we will need visions such as this to overcome it and achieve better ways to be.

There are three versions of this digital painting available for free download (left-click on the links to open, right-click to download):

Small (1200 by 1931 pixels)

Medium (2400 by 3861 pixels)

Original Size (11250 by 18100 pixels – a vast canvas with immense detail. Note: This file size is immense as well – but you will be able to zoom in to view individual buildings and regard them as smaller-scale paintings in their own right.)

For those seeking musical accompaniment in viewing this painting, I recommend my Transhumanist March, Op. 78 (2014) (MP3 and YouTube)  or Man’s Struggle Against Death, Op. 58 (2008) (MP3 and YouTube).

Find out more about Mr. Stolyarov here.

Ekaterinya Vladinakova is an accomplished digital painter. See her gallery here and her DeviantArt page here.  

The Right to Die – Article by Martin van der Kroon

The Right to Die – Article by Martin van der Kroon

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Martin van der Kroon


The U.S. Transhumanist Party is, among many other things, concerned with life extension, health, and in general the well-being of people. If life extension can be stretched to virtual immortality, that would be even more amazing, but should it be mandatory?

This post is my personal view, and I have proposed a Plank regarding this which has been added to the Exposure Period for Platform Vote #5I’m not trying to convince people, but I would like to open the discussion on a topic that we may reasonably call controversial.

Read More Read More

U.S. Transhumanist Party Presence at RAAD Fest on August 9-13, 2017 – The Revolution Against Aging and Death Has No Borders

U.S. Transhumanist Party Presence at RAAD Fest on August 9-13, 2017 – The Revolution Against Aging and Death Has No Borders

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Gennady Stolyarov II


The United States Transhumanist Party is pleased to announce that it will have extensive representation at the 2017 RAAD Fest in San Diego on August 9-13. Gennady Stolyarov II, Chairman of the U.S. Transhumanist Party and Chief Executive of the Nevada Transhumanist Party, will deliver a 10-minute speech prior to moderating a panel of illustrious life-extension advocates, philosophers, and researchers. For a preview of Mr. Stolyarov’s speech, see the overview below.

The U.S. Transhumanist Party: Pursuing a Peaceful Political Revolution for Longevity

Overview: Today’s political systems are bitter and polarized because of a scarcity and a zero-sum mentality. Transhumanism promises a future of widespread abundance that overcomes today’s major sources of scarcity – particularly the scarcity of time that arises with today’s woefully short lifespans. The U.S. Transhumanist Party represents a new political paradigm that seeks primarily to influence public opinion to support the feasibility and desirability of indefinite life extension as well as a wide array of other emerging technologies that could radically improve all our lives. We are already pursuing a revolutionary new approach to politics through our free and open membership, electronic ranked-preference voting, member-driven platform, and transpartisan embrace of all thinkers who can help constructively shape a future of radical and universal flourishing.

The U.S. Transhumanist Party – Pursuing a Future of Extreme Progress – Presentation by Gennady Stolyarov II

The U.S. Transhumanist Party – Pursuing a Future of Extreme Progress – Presentation by Gennady Stolyarov II

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Gennady Stolyarov II


Listen to and download the audio recording of this presentation at http://rationalargumentator.com/USTP_Future_of_Extreme_Progress.mp3 (right-click to download).

Download Mr. Stolyarov’s presentation slides at http://rationalargumentator.com/USTP_Future_of_Extreme_Progress.pdf (right-click to download).


Gennady Stolyarov II, Chairman of the U.S. Transhumanist Party, delivered this presentation virtually at the Extreme Futures Technology and Forecasting (EFTF) Work Group on March 11, 2017.

Mr. Stolyarov outlines the background and history of the Transhumanist Party, its Core Ideals, its unique approach to politics and member involvement, and the hopes for transforming politics into a constructive focus on solutions to the prevailing problems of our time.

At the conclusion of the presentation Mr. Stolyarov answered a series of questions from futurists Mark Waser and Stuart Mason Dambrot.

Become a member of the U.S. Transhumanist Party for free here.

Watch the U.S. Transhumanist Party Discussion Panel on Artificial Intelligence here.

Watch the U.S. Transhumanist Party Discussion Panel on Life Extension here.

Benchmark Database of Lifespan-Extending Drugs Announced – Press Release by Biogerontology Research Foundation

Benchmark Database of Lifespan-Extending Drugs Announced – Press Release by Biogerontology Research Foundation

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Note from the Editor: The following Press Release was originally published on EurekAlert! Science News by the Biogerontology Research Foundation. In accord with the U.S. Transhumanist Party’s open support of longevity science – in particular, Article V and Article VI of the Transhumanist Bill of Rights (v. 2.0) – we affirm our support by republishing the Press Release below.

~ B.J. Murphy, Director of Social Media, United States Transhumanist Party, March 16, 2017


Benchmark database of lifespan-extending drugs announced

Finding: The majority of age-related pathways have yet to be targeted pharmacologically

BIOGERONTOLOGY RESEARCH FOUNDATION

Scientists from the Biogerontology Research Foundation (BGRF) and University of Liverpool have announced a landmark database of lifespan-extending drugs and compounds called DrugAge. The database has 418 compounds, curated from studies spanning 27 different model organisms including yeast, worms, flies and mice. It is the largest such database in the world at this time. Significantly, the study found that the majority of age-related pathways have not yet been targeted pharmacologically, and that the pharmacological modulation of aging has by and large focused upon a small subset of currently-known age-related pathways. This suggests that there is still plenty of scope for the discovery of new lifespan-extending and healthspan-extending compounds.

DrugAge is the latest of a number of valuable resources freely available on the Human Aging Genomic Resources (HAGR) website created and maintained by the Integrative Genomics of Ageing Group at the University of Liverpool, led by Biogerontology Research Foundation Trustee Joao Pedro de Magalhaes, in collaboration with many other scientists worldwide, including BGRF Chief Science Officer and CEO of Insilico Medicine, Alex Zhavoronkov, PhD. Other resources available through HAGR include GenAge (a database of age and longevity-related genes in humans and model organisms), AnAge (a database on ageing, longevity records and life-history featuring over 4000 species), GenDR (a database of genes associated with the life extending effects of dietary restriction), and LongevityMap (a database of over 2000 human genes and genetic variations associated with longevity).

“DrugAge is the latest database created by Joao Pedro de Magalhaes, a world leader in the application of advanced bioinformatics and integrated computational approaches to biogerontology and ageing research. I am confident that it will gain widespread use in the ageing research community, and represents a significant milestone along the way to the coming paradigm shift in modern healthcare away from single disease treatment and toward geroprotective multi-disease prevention,” said Dmitry Kaminskiy, Managing Trustee of the Biogerontology Research Foundation.

The database is freely available to the public, and is searchable according to compound name, species and effect on lifespan. The data can be presented as both tables and interactive charts. Functional enrichment analysis of the targets of the database’s compounds was performed using drug-gene interaction data, which revealed a modest but statistically significant correlation between the cellular targets of the database’s compounds and known age-related genes.

The database encompasses the earlier efforts published by the BGRF scientists, Joao Pedro de Magalhaes, PhD and Alex Zhavoronkov, PhD as an open resource called Geroprotectors.org. The publication is available at http://www.aging-us.com/article/100799 .

“DrugAge represents a landmark resource for use in the biogerontology community. It is the largest database of lifespan-extending compounds compiled to date, and will surely come to be recognized as an extremely valuable resource for biogerontologists. Analysis performed using the database has already revealed interesting trends, including a modest but statistically significant overlap between lifespan-extending drugs and known age-related genes, a strong correlation between average/median lifespan changes and maximum lifespan changes, a strong correlation between the lifespan-extending effects of compounds between males and females, and perhaps most significantly that most known age-related pathways have yet to be targeted pharmacologically. More broadly, an understanding of the comparative effects of geroprotectors upon the lifespan of a variety of different model organisms is important both for basic research into the biology of ageing, demonstration of lifespan plasticity via modulation of a variety of distinct biomolecular targets as proof to regulators that healthspan extension is a viable paradigm for disease treatment and prevention, and for the eventual clinical translation of potential geroprotectors,” said Franco Cortese, Deputy Director and Trustee of the Biogerontology Research Foundation.

“Besides introducing the DrugAge database to the larger scientific community, this paper’s overarching significance lies in the finding that the large majority of known age-related pathways have not yet been targeted pharmacologically, and that we are in a very real sense at the starting line of the search for pharmacological agents capable of extending lifespan and healthspan via the modulation of known age-related pathways. There is still very much left to learn,” said Joao Pedro de Magalhaes, PhD, a Trustee of the Biogerontology Research Foundation (BGRF) and a Principal Investigator at the University of Liverpool’s Integrative Genomics of Aging Group (IGAG).

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The paper ‘The DrugAge database of ageing-related drugs’ has been published in the journal Aging Cell.

 

U.S. Transhumanist Party Discussion Panel on Life Extension – February 18, 2017

U.S. Transhumanist Party Discussion Panel on Life Extension – February 18, 2017

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Gennady Stolyarov II


Listen to and download the audio recording of this panel discussion at http://rationalargumentator.com/USTP_Life_Extension_Panel.mp3 (right-click to download).

For its second expert panel, the U.S. Transhumanist Party invited Bill Andrews, Aubrey de Grey, Ira Pastor, and Ilia Stambler to discuss life extension and the quest to reverse biological aging through science and technology.

This two-hour panel discussion, moderated by Chairman Gennady Stolyarov II, took place on Saturday, February 18, 2017, at 10 a.m. U.S. Pacific Time. In this interactive venue, many opportunities for fresh discourse arose on the possibility of achieving dramatically greater longevity within our lifetimes. The substance of the discussion begins at 4:25 in the recording.

Questions the panelists considered include the following:

(i) How would you characterize the current state of efforts to reverse senescence / lengthen human lifespans?
(ii) How does progress in the areas of research you have delved into compare to your expectations approximately 10 to 15 years ago?
(iii) What are the most significant challenges and obstacles that you perceive to exist in the way of achieving serious reversal of biological aging?
(iv) What key technologies and methods of delivering treatments to patients would need to be developed in order for longevity escape velocity to be affordably achieved society-wide?
(v) What political reforms and societal / attitudinal changes would you advocate to accelerate the arrival of effective treatments to reverse biological aging and lengthen lifespans?
(vi) Are you concerned about any current political trends and how they might affect the progress of research into combating biological aging?
(vii) What can laypersons who are sympathetic to your goals do in order to hasten their realization? How can the effort to defeat aging become as popular and widely supported as efforts to defeat cancer and ALS are today?
(viii) What lessons can the history of anti-aging research offer to those who seek to advocate and help achieve effective scientific breakthroughs in this area in the coming years and decades?

References

Genetic stabilization of transthyretin, cerebrovascular disease, and life expectancy” – Paper by Louise S. Hornstrup, Ruth Frikke-Schmidt, Børge G. Nordestgaard and Anne Tybjærg-Hansen. Arteriosclerosis, Thrombosis, and Vascular Biology. 2013;33:1441-1447, Originally published May 15, 2013.

Recognizing Degenerative Aging as a Treatable Medical Condition: Methodology and Policy” – Paper by Ilia Stambler. Aging and Disease.

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Panelists

Dr. Bill Andrews is the President and CEO of Sierra Sciences – http://www.sierrasci.com/. As a scientist, athlete, and executive, he continually pushes the envelope and challenges convention. In his 35-year biotech career, he has focused the last 23 years on finding ways to extend the human lifespan and healthspan through telomere maintenance. As one of the principal discoverers of both the RNA and protein components of human telomerase, Dr. Andrews was awarded 2nd place as “National Inventor of the Year” in 1997.

Dr. Aubrey de Grey is the biomedical gerontologist who researched the idea for and founded SENS Research Foundation – http://www.sens.org/. He received his BA in Computer Science and Ph.D. in Biology from the University of Cambridge in 1985 and 2000, respectively. Dr. de Grey is Editor-in-Chief of Rejuvenation Research, is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the editorial and scientific advisory boards of numerous journals and organizations.

Ira Pastor has 30 years of experience across multiple sectors of the pharmaceutical industry, including pharmaceutical commercialization, biotech drug development, managed care, distribution, OTC, and retail. He is the CEO of BioQuark, Inc. – http://www.bioquark.com/ – and Executive Chairman of ReAnima Advanced Biosciences – https://reanima.tech/.

Dr. Ilia Stambler is a researcher at Bar Ilan University, Israel. His research focuses on the historical and social implications of aging and life-extension research. He is the author of A History of Life-extensionism in the Twentieth Century – www.longevityhistory.com. He is actively involved in advocacy for aging and longevity research – www.longevityforall.org.