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Anti-Aging: The Growing Popularity Of Radical Life Extension – Article by Kimberly Forsythe

Anti-Aging: The Growing Popularity Of Radical Life Extension – Article by Kimberly Forsythe

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Kimberly Forsythe


There are numerous anti-aging therapies, which are used to slow the aging process in humans. Each of these therapies has its own advantages and disadvantages. For example, there are anti-aging processes such as anti-oxidants, anti-aging nutrients, anti-aging exercise programs, anti-aging diets, and anti-aging supplements that are said to extend a person’s lifespan. Aging is said to be a natural process that cannot be slowed or reversed once humans undergo it, and which accelerates greatly after puberty and early adulthood; however, some experts do not agree with this. There are several theories on the subject of aging that have varying outlooks on the actual causes of aging.

What Causes Aging in Humans?

There are various theories that explain the causes of aging, but they do not all agree. While we are making new discoveries all the time, we still do not have definitive answers on what causes aging. Some researchers believe that oxidative damage is what causes aging, and others believe genetics are involved in causing aging.

The evidence for the oxidative damage by sunlight, poor diet, and poor exercising habits is strong. For example, if your parents or grandparents had a shorter lifespan than the average person, it’s possible that part of the reason was that they didn’t have a good diet, they didn’t exercise, or they didn’t avoid the common environmental hazards we encounter today. That certainly makes some sense.

You might think that they all contribute equally, which is certainly plausible. Consider how much impact the food we eat has on our health. If the foods we eat are generally unhealthy, then the oxidative damage done to our cells will be greater, and our lifespan will be shortened. If the foods we eat are rich in antioxidants and are beneficial to health, then we will be healthier, and the oxidative damage we do to our cells will be lessened.

So, one could say that oxidative damage is what causes aging, and the antioxidants are what counteract it. But that’s too simple. Actually, free radicals do more damage to our cells than oxidative damage, so it stands to reason that free radicals add to the damage. In other words, instead of wearing away at the cells in a chemical process, free radicals cause cell death.

However, the evidence for genetics is also strong. When the telomeres within the protective shell of the cell are damaged, they become shorter. As a result, the “RNA” within the telomere becomes too short. The second factor which causes aging is cell senescence, or aging at the cellular level.

There are many different forms of cell senescence, but the main ones are in peripheral tissues such as skin, muscles, and blood vessels. If this continues, then the total number of cells may start to decline. The decline in cell numbers is partly what causes aging in general.

Another factor is called DNA damage, and this is caused by exposure to radiation and to chemicals used during manufacturing. This is a big problem, because DNA is responsible for the repair of cellular damage, and if it gets damaged, it can stop replicating to produce new cells altogether. This would mean that the aging process could not be stopped, and the body will just keep getting older without any real control.

What is Radical Life Extension?

Radical life extension is the process of using anti-aging technology to reverse age-related processes that are already underway. Anti-aging techniques rely on a combination of knowledge and understanding of the aging process, as well as on modern-day scientific breakthroughs. Scientists are only just now beginning to unlock many of the mysteries surrounding the mechanisms of aging.

In theory, we could live forever if we found a way to completely rejuvenate ourselves after we passed the age of sixty. Some people are under the impression that curing or reversing aging is impossible. But at the very least, we might be able to make ourselves better, or at least age gracefully. It is not known how far the search has come, but some of the results so far have been very promising.

When Will Aging be Cured or Reversed?

To cure or reverse aging, it will be necessary to find some way to increase the lifespan of humans. Many questions surround which scientific approach to anti-aging will be the most beneficial to humans. Perhaps we will lengthen lifespans by curing all of the diseases that we are prone to, or perhaps by using genetic engineering to insert new genes into the human genome. For some transhumanists, the ultimate aim would be to live forever. Others, however, wish only to increase the number of healthy years.

There is a great deal of interest in the subject of radical life extension, and there is considerable money involved. Investors are piling in to fund research to unlock more theories about aging and the mysteries that scientists are trying to unravel. There are, unfortunately, many unfounded claims and charlatans out there misleading the public about how we may be able to cure or reverse aging.

Some people have made the mistake of thinking that radical life extension is magic, or of taking a magical pill that will turn you into an immortal. While there is promising research for medications that can reduce biological age, the notion that it will be an immediate and instant cure is likely a distortion of the truth. We need to understand that aging is just one of the processes that occur within us, but there are many ways we can counter these processes. It is possible to extend your life significantly, but this requires an understanding of the aging process as a whole.

Overall, the more resources we put into studying the aging process and search for effective ways of curing or reversing aging, the faster we will find answers to questions that humans have sought after for ages. The “Fountain of Youth” may arrive sooner than we think. It is important that we collectively understand the implications of reversing aging and take steps to address these issues as soon as possible.

Related reading:

Healthier, longer lifespans will be a reality sooner than you think, Juvenescence promises as it closes $100M round

Opinions From Around the World: Obah Isaac Ebuka – 3D-Printing Organs for Transplant

Opinions From Around the World: Obah Isaac Ebuka – 3D-Printing Organs for Transplant

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Obah Isaac Ebuka


Editor’s Note: It is extremely important that supporters of transhumanism understand the opinions of peoples from every nation. I, Kimberly Forsythe, decided to reach out to people from other cultures and asked them to give me their opinions on the topic of transhumanist tech. My goal is to better understand why some may object to the idea based on various cultural differences.

As I receive the essays, I will publish them. My hope is that we can work together to build more international bridges and achieve progress that works for as many people as possible. This essay regarding the promises of 3D-printing of organs and the remaining challenges of implementing this technology was written by Obah Isaac Ebuka. 

~ Kimberly Forsythe, Member, United States Transhumanist Party, December 13, 2020


3D-Printing Organs for Transplant

What if it was possible to mass-produce organs – to grow hearts and lungs in a lab, readily accessible by the hundreds of thousands of patients waiting for organs? The affirmative answer to that question has been the goal of many researchers over the years, and their results are very promising.

The Promise of 3D-Printing

In 1988, a researcher modified a basic HP inkjet printer into using cells instead of regular ink and used the printer to write on a surface using cytoscribing technology. Now in 2019, scientists in Israel have been able to print a miniature human heart complete with contracting blood vessels using human cells. A lot of work and technology through the years led up to this incredible feat of human bio-engineering.

3D-printing organs is still not completely perfected, but the technology at present shows that it is possible. Current biotechnology makes it possible to print incredibly complex organ scaffold structures that mimic the structures of human organs and tissues with high anatomical precision using synthetic but biocompatible materials. These scaffolds can then be used as the spatial matrix on which cells can be built upon to create life-sized vascularized organs that possess the vital microstructures of real organs.

Current Challenges for Bioprinting

Biological Complexity

There are still many challenges to bioprinting that are yet to be addressed. One of these is that human organs are more incredibly complex than current technology can create. It might have been possible to create a miniature heart with the major aortae and coronary arteries, but scientists have yet to replicate vessel structures like the millions of capillary networks which are micrometers in diameter and essential to the life of organs.

Also, organs are much more than their structures and shapes. There a lot of details about organs that we are yet to understand such as how certain genes, hormones, and other factors in the body interact with organs and vice versa. An example of this is how the heart is an endocrine organ and not simply a blood pumper. So a true heart replacement also has to be able to create Atrial Natriuretic Peptides (ANP), which lower blood pressure.

Practicability

Hindrances from a bioengineering perspective aren’t the only things to worry about. It is also very challenging to design clinical trials that will test the longevity and compatibility of these experimental organs in humans. There is also the challenge of securing sustainable sources of cells, biocompatible material, as well as large-scale manufacturing capabilities needed for 3D-printing to be a viable and affordable replacement for real organ transplants.

Ethnic and Religious beliefs

Ethnicity and religious belief inhibit technological changes. In Nigeria, a country in western Africa, some groups of religious fanatics believe that each organ is sacred and would not have their organs changed. This view is not only shared in Nigeria particularly, but it is commonplace and widespread for natives to abhor mending or replacing what they come to see as natural.

Proposed solutions to these barriers

Natives should be enlightened. They should be taught the need for bioprinting organs, seeing that the ultimate aim is to save lives.

Author: Obah Isaac Ebuka

Abuja, Nigeria.

Twitter handle: @AiTweet01

Opinions From Around The World: Mert Basoglu – The Cautionary Tale of Neuralink

Opinions From Around The World: Mert Basoglu – The Cautionary Tale of Neuralink

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Mert Basoglu


Editor’s Note: It is extremely important that supporters of transhumanism understand the opinions of peoples from every nation. I, Kimberly Forsythe, decided to reach out to people from other cultures and asked them to give me their opinions on the topic of transhumanist tech. My goal is to better understand why some may object to the idea based on various cultural differences.

As I receive the essays, I will publish them. My hope is that we can work together to build more international bridges and achieve progress that works for as many people as possible. This commentary on Elon Musk’s Neuralink was written by Mert Basoglu from Istanbul, Turkey.

~ Kimberly Forsythe, Member and Assistant Editor, United States Transhumanist Party, December 11, 2020


The Cautionary Tale of Neuralink

Elon Musk has been in the public eye with his innovations and ambitious projects in various fields such as aerospace, electric car manufacturing, and lately, neurotechnology. Even though I find most of his ideas and innovations worthy of admiration, I believe Neuralink and brain-machine interfaces (BMIs), in general, are somewhat problematic at this stage of human evolution.

First and foremost, I am all for Musk’s idea of treating neurological diseases that used to be untreatable. In consideration, Neuralink’s benefit to society in terms of both physical and mental health would be undeniable if it’s used correctly and responsibly. But, given our history of violence, abuse, and exploitation, I believe we are not ready for this kind of invention as of yet. It is an irrefutable fact that (BMIs) such as Neuralink are highly prone to being misused and weaponized for self-interests or political reasons. This may be a pessimistic view; however, I think of it as a realistic one, as there are oceans of such examples in our history. As a result of this, I think Neuralink or other (BMIs) are revolutionary and great inventions that should have emerged in the future, when our collective consciousness and empathy as a society hopefully progressed further.

Apart from these topics, there are many other concerns regarding Neuralink that beg to be discussed and solved. One example could be the topic of individualism; the paradox of creating a ‘database’ or ‘network’ that is filled with our ‘individual’ thoughts. It begs the question; what happens to the sense of self? Are our thoughts impersonal now? If we transcend humanity, become a collectively transhuman entity, where does our inevitable evil and hunger for destruction go?

To end on a positive note, I would love Neuralink or other BMIs to be useful inventions that we regularly use in our daily lives, but I think we, as humanity, have to cut our afflictions at the roots first.

– Mert Basoglu

Istanbul, Turkey

Opinions From Around The World: Abdeldayem Hassanein – Bionics and Other Emerging Technologies

Opinions From Around The World: Abdeldayem Hassanein – Bionics and Other Emerging Technologies

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Abdeldayem Hassanein


Editor’s Note: It is extremely important that supporters of transhumanism understand the opinions of peoples from every nation. I, Kimberly Forsythe, decided to reach out to people from other cultures and asked them to give me their opinions on the topic of transhumanist tech. My goal is to better understand why some may object to the idea based on various cultural differences.

As I receive the essays, I will publish them. My hope is that we can work together to build more international bridges and achieve progress that works for as many people as possible. This first essay was written by Abdeldayem Hassanein, an MD and medical writer from Egypt.

He was already familiar with some aspects of transhumanism, especially the areas of bionics and nanotechnology. I asked him to write a piece from his point of view. Here is Abdeldayem’s essay in its entirety.

~ Kimberly Forsythe, Member, United States Transhumanist Party, December 4, 2020


“A person can never be broken. Our built environment, our technologies, are broken and disabled.”

~ Hugh Herr

Hugh Herr, a victim of leg amputation, said the above sentence during a presentation where he expressed his opinion about bionics. Bionics are prostheses that combine the qualities of both technology and biology. The bionic leg has three attachment layers to the human body: mechanical, biological, and electrical. Joints are supplemented with a special metallic blade sensitive to body voltage. With voltage zero, the blade relaxes while with 1-degree voltage, the blade stiffens, enabling the handicapped to walk without support. The equipment is attached to the nerve ending at the site of amputation. Hugh was injured by frostbite after falling while he was climbing a mountain. [3]

Bionics are categorized under the “Human+” outlook, a philosophy encouraging innovation and updating. Yet, some nations hate some aspects of this philosophy like its seeking for immortality on Earth, age conversion, as well as its experimentation with genetic materials.

In 2017, eye bionics appeared. An elder patient with an eye disease called retinitis pigmentosa, with decades of blindness, all of a sudden shouted in happiness after a surgical operation where sensors were implanted in his eye retinae and were combined with eyeglasses supplemented with a camera. He found himself capable of differentiating between orange trees and apple trees. He could watch TV but without color discrimination. [4]

Scientists in the Biotechnology department in one bionic center spent 200 days evaluating the mode of manufacture of a leg for a female dancer  who lost her leg after a blast injury in Afghanistan. She could successfully return to her beloved dancing. [2]

Hand prostheses previously were only cosmetic. With bionics, however, the amputated person can play with cards, open a door with a key, shake the hand, count the currency precisely, and drive a car. It was a dramatic moment when a pretty girl of 20 years old, who was born mute due to congenital anomalies in her ears, started to hear after implantation of metallic sensors near the eight cranial nerves – devices which provided her with sound magnifiers. [1] [5]

It appears that science is a double-edged weapon. Aspirin, the first drug lowering fever, was abused during the Spanish Influenza pandemic and caused a lot of toxicities from an overdose. Thalidomide, a drug supposed to calm pregnant ladies, was an investigational drug under the supervision of German and American researchers. The German regulatory body was in hurry to pass Stage 3 of evaluation and allowed German citizens to use thalidomide while pregnant, while the American regulators preferred to postpone its usage for further evaluation. The result was the birth in Germany of a couple of babies with serious congenital anomalies called Phaecomalia, where the baby lacks both arms and legs.

Transhumanists are not always welcomed. The so-called Haredi Jews in Jerusalem are conservative to the degree that they disallow TV inside the home, allow Internet only at work, and disallow couples meeting except in the dark. Such a style makes them resistant to many activities of the Transhumanists. [7]

Some historians think that science alone is not sufficient to lead humans to utopia. Also, the classic way of research, including meta-analysis, systematic review, and even experimental studies would not be sufficient to alleviate all human sufferings. Scientists made a lot of efforts in search for COVID-19 vaccine, while a only little effort was devoted to investigating the disappearance of half a trillion bees inside the USA during only the past 14 years, a phenomenon is known as Colony Collapse Disorder. Bees are required for forest pollination and hence may help reduce ground-level ozone pollution by supporting forests that absorb ground-level ozone. Without this effect, the phenomenon of global warming may be accelerated.

However, there is some hope in regard to adoption of emerging technologies throughout the world. For example, nanotechnology supplies gold nanoparticles to treat cancer of the female genital tract, and the materials are considered cheap. Some hospitals use nano-painting due to its bactericidal effects. [8]

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[1] Connolly, Christine. “Prosthetic hands from touch bionics.” Industrial Robot: An International Journal 35, no. 4 (2008): 290-293.

[2] Rouse, Elliott J., Nathan C. Villagaray-Carski, Robert W. Emerson, and Hugh M. Herr. “Design and testing of a bionic dancing prosthesis.” PloS one 10, no. 8 (2015): e0135148.

[3] Herr, Hugh M., and Alena M. Grabowski. “Bionic ankle-foot prosthesis normalizes walking gait for persons with leg amputation.” Proceedings of the Royal Society B: Biological Sciences 279, no. 1728 (2012): 457-464.

[4] Coffey, Valerie C. “Vision accomplished: the bionic eye.” Optics and Photonics News 28, no. 4 (2017): 24-3.

[5] Kral, Andrej, and Thomas Lenarz. “How the brain learns to listen: deafness and the bionic ear.” Neuroforum 21, no. 1 (2015): 21-28.

[6] Kribs-Zaleta, Christopher M., and Christopher Mitchell. “Modeling colony collapse disorder in honeybees as a contagion.” Mathematical Biosciences & Engineering 11, no. 6 (2014): 1275.

[7] Friedman, Menachem. “The Haredi (ultra-orthodox) society: Sources, trends and processes.” Jerusalem: The Jerusalem Institute for Israel Studies (1991).

[8] Naddafi, K., H. Jabbari, and M. Chehrehei. “Effect of nanosilver painting on control of hospital air-transmitted microorganisms.” Journal of Environmental Health Science & Engineering 7, no. 3 (2010): 223-228.

U.S. Transhumanist Party 2019 Electronic Primary Results – Johannon Ben Zion Endorsed as Candidate for President of the United States

U.S. Transhumanist Party 2019 Electronic Primary Results – Johannon Ben Zion Endorsed as Candidate for President of the United States


October 1, 2019 – The U.S. Transhumanist Party / Transhuman Party (USTP) hereby announces the results of its 2019 Electronic Primary for the USTP’s endorsement of a candidate to run for the office of President of the United States. Detailed results have been tabulated here.

Between 8:30 p.m. Pacific Time on September 21, 2019, and 6:00 p.m. on September 30, 2019, 312 members of the USTP cast their ballots in the first-ever competitive USTP primary election among candidates. Consistent with the USTP’s commitment to ranked-preference voting, which is superior and more representative than single-choice plurality voting, this ballot required voters to rank-order all candidate options (nine candidates and “None of the Above” – which could have been selected as first, last, or in the middle of your options). While candidate Kimberly Forsythe withdrew from the race as voting was ongoing, candidates Johannon Ben Zion, Kristan T. Harris, Rachel Haywire, Charles Holsopple, John J. Kerecz, Jonathan Schattke, Matt Taylor, and Vrillon remained as choices on the ballot for voters to select until the end. The first 170 ballots that included Candidate Forsythe were subject to a de facto instant runoff where, after the removal of Candidate Forsythe, all of the choices which voters ranked less favorably than her were elevated by one ranking.

All votes cast during the election process were manually validated to ensure that they originated from genuine USTP members. While several duplicate votes were discarded, the USTP leadership believes that those votes were inadvertent and the result of technical difficulties or misunderstandings experienced by a small number of members. Detailed monitoring of the votes cast did not detect any voter fraud, sock-puppet accounts, or mass attempts by non-members to vote. USTP leadership is thus confident that election security was appropriately preserved.

After the entire 312 ballots were cast, an instant-runoff process was undertaken, and seven rounds of instant runoffs were required before a candidate achieved a numerical majority of reassigned votes. The instant-runoff process, along with the entirety of the anonymized individual ballots (ordered by randomly assigned Voter IDs to protect individual voters’ privacy), has been documented in this spreadsheet. The “manual” (Excel-based) instant-runoff process was externally validated by another, automated mechanism:  the open-source Instant-Runoff Voting Tool, developed by Peter Grassberger and available at https://petertheone.github.io/IRV/. The linked text file contains the inputs entered into the Instant-Runoff Voting Tool to produce output that exactly matched the results obtained through the USTP’s own internal calculation process. USTP leadership is thus confident in the accuracy of the instant-runoff calculations.

Below is a summary of the voter rankings given to each candidate that remained on the ballot until the conclusion of the election.

The candidates accordingly began the instant-runoff process with the following vote totals.

Round 1: Tally of First Choices

Johannon Ben Zion: 109 votes – 34.94%
Rachel Haywire:          72 votes – 23.08%
Kristan T. Harris:       35 votes – 11.22%
Charles Holsopple:     30 votes – 9.62%
John J. Kerecz:            19 votes – 6.09%
Matt Taylor:                  17 votes – 5.45%
None of the Above:     13 votes – 4.17%
Vrillon:                           9 votes – 2.88%
Jonathan Schattke:     8 votes – 2.56%

In Round 7 of the instant-runoff process, candidate Johannon Ben Zion achieved a majority of the reallocated votes.

Round 7: Tally of First Choices after Reassignment

Johannon Ben Zion: 160 votes – 51.28%
Rachel Haywire:              97 votes – 31.09%
Charles Holsopple:         55 votes – 17.63%

Therefore, Johannon Ben Zion has won the USTP 2019 Electronic Primary. Candidate Ben Zion is both the ranked-preference winner and the plurality winner of the election. Moreover, his lead in both absolute and relative terms is substantial and remained the case throughout the voting process.

In accordance with the preferences of the USTP membership, on October 1, 2019, USTP Chairman Gennady Stolyarov II declared pursuant to his authority in Article II of the USTP Constitution that the United States Transhumanist Party / Transhuman Party hereby endorses Johannon Ben Zion for President of the United States in the 2020 general election.

Officially Candidate Ben Zion will be running as an independent candidate and will be personally responsible for any fundraising (should he choose to engage in it) and compliance with registration and campaign-finance requirements. However, the USTP and its team of Officers and volunteers will assist Candidate Ben Zion in any manner that is lawful and practicable. Moreover, if Candidate Ben Zion qualifies for inclusion on any States’ ballots, then, in approximately half of the jurisdictions in the United States, it would be possible to use a “political party designation” of “Transhumanist Party” to accompany the candidate’s name on the ballot.

The USTP leadership congratulates Johannon Ben Zion on his victory and looks forward to working with his campaign to maximize public awareness of the ideas of transhumanism and the many constructive policy applications to these ideas can be put. The USTP also encourages all of its members, and all transhumanists generally, to support the Ben Zion 2020 campaign and unite as a movement in advocating for the ideas of transhumanism to the general public. The candidacy of Johannon Ben Zion, with appropriate input and guidance from a broad spectrum of transhumanists – including those who supported other candidates in this election – can become a powerful vehicle for mainstreaming transhumanist aspirations. No matter whom you voted for in the primary, we welcome your support in this next stage of our endeavors – and we welcome other candidates continuing an active role in the projects of the USTP, including potentially pursuing other political offices.

Third Virtual Debate Among U.S. Transhumanist Party Presidential Candidates – September 14, 2019

Third Virtual Debate Among U.S. Transhumanist Party Presidential Candidates – September 14, 2019

John J. Kerecz
Charles Holsopple
Rachel Haywire
Kimberly Forsythe
Kristan T. Harris
Moderated by Gennady Stolyarov II


The Third Virtual Debate among the U.S. Transhumanist Party Presdidential Primary candidates has been the highest-quality and most substantive debate yet! Watch it here.

The first of the final two official debate segments among the U.S. Transhumanist Party / Transhuman Party primary candidates for President of the United States occurred on Saturday, September 14, 2019, at 5 p.m. Pacific Time and was co-hosted by Steele Archer of the Debt Nation show. In this segment candidates John J. Kerecz, Charles Holsopple, Rachel Haywire, Kimberly Forsythe, and Kristan T. Harris answered crowdsourced questions on character and leadership, radical life extension, health care, universal basic income, foreign policy, the U.S. federal budget, and various other matters.

See the original debate stream on the Debt Nation show here, including the pre-debate and post-debate shows held on the same day.

Learn about the USTP candidates here.

View individual candidate profiles (5 of 9 candidates spoke in this debate; the remaining 4 are scheduled to speak on Tuesday, September 17, 2019):

All of the candidates were thoughtful, substantive, and contributed many excellent ideas to a complex and civil discussion. We hope for the same with the September 17, 2019, Fourth Virtual Debate among Candidates Johannon Ben Zion, Jonathan Schattke, Matt Taylor, and Vrillon! (Tune into The Unshackled YouTube channel to watch that debate live at 6:30 p.m. Pacific Time on September 17, 2019.)

Join the USTP for free here, no matter where you reside. Those who join by September 21, 2019, will be eligible to vote in the Electronic Primary which will begin on the next day.

Announcement of Third and Fourth Virtual Debates Among U.S. Transhumanist Party Presidential Candidates – Gennady Stolyarov II Interviewed by Steele Archer of Debt Nation

Announcement of Third and Fourth Virtual Debates Among U.S. Transhumanist Party Presidential Candidates – Gennady Stolyarov II Interviewed by Steele Archer of Debt Nation

Gennady Stolyarov II
Steele Archer


On September 10, 2019, U.S. Transhumanist Party / Transhuman Party Chairman Gennady Stolyarov II was again interviewed by Steele Archer of Debt Nation, this time to discuss the two forthcoming official final virtual debates of the U.S. Transhumanist Party Presidential primary season.

Watch the interview here.

3rd Virtual Debate: Candidates Forsythe, Harris, Haywire, Holsopple, and Kerecz – Saturday, September 14, 2019, at 5:00 p.m. U.S. Pacific Time – See more details here.

4th Virtual Debate: Candidates Ben Zion, Schattke, Taylor, and Vrillon – Tuesday, September 17, 2019 at 6:30 p.m. U.S. Pacific Time – See more details here.

The Debt Nation show will co-host the debates, which will be livestreamed from The Unshackled YouTube channel.

Remember to join the U.S. Transhumanist Party for free before September 21, 2019, in order to be eligible to vote in the Electronic Presidential Primary that follows. Join here, no matter where you reside.